| Full name: antizyme inhibitor 1 | Alias Symbol: OAZI|ODC1L | ||
| Type: protein-coding gene | Cytoband: 8q22.3 | ||
| Entrez ID: 51582 | HGNC ID: HGNC:16432 | Ensembl Gene: ENSG00000155096 | OMIM ID: 607909 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of AZIN1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AZIN1 | 51582 | 212461_at | 0.3944 | 0.1888 | |
| GSE20347 | AZIN1 | 51582 | 212461_at | 0.0696 | 0.7726 | |
| GSE23400 | AZIN1 | 51582 | 212461_at | 0.4278 | 0.0000 | |
| GSE26886 | AZIN1 | 51582 | 212461_at | -0.5301 | 0.0282 | |
| GSE29001 | AZIN1 | 51582 | 212461_at | 0.0745 | 0.8749 | |
| GSE38129 | AZIN1 | 51582 | 212461_at | 0.1383 | 0.3249 | |
| GSE45670 | AZIN1 | 51582 | 212461_at | -0.2370 | 0.1727 | |
| GSE53622 | AZIN1 | 51582 | 60722 | 0.1451 | 0.0107 | |
| GSE53624 | AZIN1 | 51582 | 78950 | 0.0202 | 0.7315 | |
| GSE63941 | AZIN1 | 51582 | 201772_at | 0.8920 | 0.0586 | |
| GSE77861 | AZIN1 | 51582 | 212461_at | 0.0943 | 0.7651 | |
| GSE97050 | AZIN1 | 51582 | A_33_P3319491 | -0.3727 | 0.3974 | |
| SRP007169 | AZIN1 | 51582 | RNAseq | -0.3870 | 0.2902 | |
| SRP008496 | AZIN1 | 51582 | RNAseq | -0.0210 | 0.9222 | |
| SRP064894 | AZIN1 | 51582 | RNAseq | 0.3537 | 0.1462 | |
| SRP133303 | AZIN1 | 51582 | RNAseq | 0.2555 | 0.0905 | |
| SRP159526 | AZIN1 | 51582 | RNAseq | 0.1165 | 0.6965 | |
| SRP193095 | AZIN1 | 51582 | RNAseq | 0.0835 | 0.4173 | |
| SRP219564 | AZIN1 | 51582 | RNAseq | 0.7737 | 0.1023 | |
| TCGA | AZIN1 | 51582 | RNAseq | 0.0393 | 0.3723 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by AZIN1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AZIN1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AZIN1 | 51582 | 17 | 0 | 13 | |
| GSE20123 | AZIN1 | 51582 | 18 | 0 | 12 | |
| GSE43470 | AZIN1 | 51582 | 22 | 0 | 21 | |
| GSE46452 | AZIN1 | 51582 | 24 | 0 | 35 | |
| GSE47630 | AZIN1 | 51582 | 24 | 0 | 16 | |
| GSE54993 | AZIN1 | 51582 | 0 | 20 | 50 | |
| GSE54994 | AZIN1 | 51582 | 38 | 1 | 14 | |
| GSE60625 | AZIN1 | 51582 | 0 | 4 | 7 | |
| GSE74703 | AZIN1 | 51582 | 19 | 0 | 17 | |
| GSE74704 | AZIN1 | 51582 | 12 | 0 | 8 | |
| TCGA | AZIN1 | 51582 | 59 | 1 | 36 |
Total number of gains: 233; Total number of losses: 26; Total Number of normals: 229.
Somatic mutations of AZIN1:
Generating mutation plots.
Highly correlated genes for AZIN1:
Showing top 20/566 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AZIN1 | HAX1 | 0.795694 | 3 | 0 | 3 |
| AZIN1 | USE1 | 0.77953 | 3 | 0 | 3 |
| AZIN1 | TMED8 | 0.77536 | 3 | 0 | 3 |
| AZIN1 | LONRF1 | 0.759655 | 3 | 0 | 3 |
| AZIN1 | TP53RK | 0.75645 | 3 | 0 | 3 |
| AZIN1 | LSM14A | 0.755732 | 3 | 0 | 3 |
| AZIN1 | DCAF16 | 0.74426 | 3 | 0 | 3 |
| AZIN1 | PSMB8 | 0.737307 | 3 | 0 | 3 |
| AZIN1 | GPR158 | 0.733414 | 3 | 0 | 3 |
| AZIN1 | PCMTD1 | 0.724795 | 3 | 0 | 3 |
| AZIN1 | KBTBD7 | 0.719202 | 4 | 0 | 3 |
| AZIN1 | TXLNG | 0.719158 | 3 | 0 | 3 |
| AZIN1 | IRF1 | 0.716405 | 3 | 0 | 3 |
| AZIN1 | UFC1 | 0.715984 | 3 | 0 | 3 |
| AZIN1 | N4BP2L1 | 0.71414 | 3 | 0 | 3 |
| AZIN1 | ZNF92 | 0.713981 | 3 | 0 | 3 |
| AZIN1 | DROSHA | 0.713767 | 4 | 0 | 3 |
| AZIN1 | DFFA | 0.713186 | 5 | 0 | 4 |
| AZIN1 | XRCC6 | 0.709445 | 3 | 0 | 3 |
| AZIN1 | SOX4 | 0.705805 | 3 | 0 | 3 |
For details and further investigation, click here
