| Full name: fatty acyl-CoA reductase 1 | Alias Symbol: FLJ22728|SDR10E1 | ||
| Type: protein-coding gene | Cytoband: 11p15.3 | ||
| Entrez ID: 84188 | HGNC ID: HGNC:26222 | Ensembl Gene: ENSG00000197601 | OMIM ID: 616107 |
| Drug and gene relationship at DGIdb | |||
Expression of FAR1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAR1 | 84188 | 224866_at | -0.8340 | 0.1224 | |
| GSE26886 | FAR1 | 84188 | 224866_at | -1.8204 | 0.0000 | |
| GSE45670 | FAR1 | 84188 | 224866_at | -0.3559 | 0.0480 | |
| GSE53622 | FAR1 | 84188 | 55545 | -0.8035 | 0.0000 | |
| GSE53624 | FAR1 | 84188 | 55545 | -0.8105 | 0.0000 | |
| GSE63941 | FAR1 | 84188 | 224866_at | 0.0838 | 0.8701 | |
| GSE77861 | FAR1 | 84188 | 224866_at | -0.4609 | 0.5115 | |
| GSE97050 | FAR1 | 84188 | A_24_P163920 | -0.0617 | 0.8872 | |
| SRP007169 | FAR1 | 84188 | RNAseq | -1.1094 | 0.0066 | |
| SRP008496 | FAR1 | 84188 | RNAseq | -1.0007 | 0.0000 | |
| SRP064894 | FAR1 | 84188 | RNAseq | -1.0024 | 0.0000 | |
| SRP133303 | FAR1 | 84188 | RNAseq | 0.1766 | 0.5902 | |
| SRP159526 | FAR1 | 84188 | RNAseq | -1.7268 | 0.0000 | |
| SRP193095 | FAR1 | 84188 | RNAseq | -1.0864 | 0.0000 | |
| SRP219564 | FAR1 | 84188 | RNAseq | -0.7941 | 0.0962 | |
| TCGA | FAR1 | 84188 | RNAseq | -0.2020 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 6.
Survival by FAR1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FAR1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAR1 | 84188 | 0 | 10 | 20 | |
| GSE20123 | FAR1 | 84188 | 0 | 10 | 20 | |
| GSE43470 | FAR1 | 84188 | 1 | 5 | 37 | |
| GSE46452 | FAR1 | 84188 | 7 | 5 | 47 | |
| GSE47630 | FAR1 | 84188 | 3 | 11 | 26 | |
| GSE54993 | FAR1 | 84188 | 3 | 1 | 66 | |
| GSE54994 | FAR1 | 84188 | 4 | 12 | 37 | |
| GSE60625 | FAR1 | 84188 | 0 | 0 | 11 | |
| GSE74703 | FAR1 | 84188 | 1 | 3 | 32 | |
| GSE74704 | FAR1 | 84188 | 0 | 9 | 11 | |
| TCGA | FAR1 | 84188 | 13 | 31 | 52 |
Total number of gains: 32; Total number of losses: 97; Total Number of normals: 359.
Somatic mutations of FAR1:
Generating mutation plots.
Highly correlated genes for FAR1:
Showing top 20/1258 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAR1 | BACH1 | 0.840454 | 3 | 0 | 3 |
| FAR1 | CYP2J2 | 0.792591 | 5 | 0 | 5 |
| FAR1 | MAML3 | 0.781532 | 3 | 0 | 3 |
| FAR1 | SMIM5 | 0.779636 | 6 | 0 | 6 |
| FAR1 | PAX9 | 0.778804 | 6 | 0 | 6 |
| FAR1 | EP300-AS1 | 0.766737 | 3 | 0 | 3 |
| FAR1 | ARHGAP27 | 0.762956 | 7 | 0 | 7 |
| FAR1 | CYP2C9 | 0.76028 | 6 | 0 | 6 |
| FAR1 | CPT2 | 0.757698 | 4 | 0 | 4 |
| FAR1 | RETSAT | 0.757152 | 3 | 0 | 3 |
| FAR1 | CCNYL1 | 0.756324 | 4 | 0 | 4 |
| FAR1 | CAPN14 | 0.756103 | 6 | 0 | 6 |
| FAR1 | RIOK3 | 0.748732 | 7 | 0 | 7 |
| FAR1 | TMEM9B | 0.745509 | 7 | 0 | 6 |
| FAR1 | CLCA4 | 0.743313 | 6 | 0 | 6 |
| FAR1 | OSTF1 | 0.741538 | 7 | 0 | 7 |
| FAR1 | EMP1 | 0.738646 | 6 | 0 | 6 |
| FAR1 | DYNLT3 | 0.738642 | 7 | 0 | 7 |
| FAR1 | VPS4B | 0.738469 | 7 | 0 | 7 |
| FAR1 | GYS2 | 0.734224 | 5 | 0 | 5 |
For details and further investigation, click here
