| Full name: sterol carrier protein 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1p32.3 | ||
| Entrez ID: 6342 | HGNC ID: HGNC:10606 | Ensembl Gene: ENSG00000116171 | OMIM ID: 184755 |
| Drug and gene relationship at DGIdb | |||
SCP2 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa03320 | PPAR signaling pathway |
Expression of SCP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SCP2 | 6342 | 211733_x_at | -0.3828 | 0.4695 | |
| GSE20347 | SCP2 | 6342 | 211733_x_at | -0.9780 | 0.0000 | |
| GSE23400 | SCP2 | 6342 | 211733_x_at | -0.5420 | 0.0000 | |
| GSE26886 | SCP2 | 6342 | 211733_x_at | -1.1123 | 0.0000 | |
| GSE29001 | SCP2 | 6342 | 211733_x_at | -0.6397 | 0.0111 | |
| GSE38129 | SCP2 | 6342 | 211733_x_at | -0.7596 | 0.0000 | |
| GSE45670 | SCP2 | 6342 | 211733_x_at | -0.4992 | 0.0066 | |
| GSE53622 | SCP2 | 6342 | 37521 | -0.8946 | 0.0000 | |
| GSE53624 | SCP2 | 6342 | 98998 | -1.0410 | 0.0000 | |
| GSE63941 | SCP2 | 6342 | 211733_x_at | -1.0763 | 0.0050 | |
| GSE77861 | SCP2 | 6342 | 211733_x_at | -1.3871 | 0.0003 | |
| GSE97050 | SCP2 | 6342 | A_23_P126057 | -0.1443 | 0.5580 | |
| SRP007169 | SCP2 | 6342 | RNAseq | -2.1459 | 0.0000 | |
| SRP008496 | SCP2 | 6342 | RNAseq | -1.8694 | 0.0000 | |
| SRP064894 | SCP2 | 6342 | RNAseq | -0.6471 | 0.0005 | |
| SRP133303 | SCP2 | 6342 | RNAseq | -0.6395 | 0.0000 | |
| SRP159526 | SCP2 | 6342 | RNAseq | -0.9652 | 0.0035 | |
| SRP193095 | SCP2 | 6342 | RNAseq | -1.5520 | 0.0000 | |
| SRP219564 | SCP2 | 6342 | RNAseq | -0.9185 | 0.0042 | |
| TCGA | SCP2 | 6342 | RNAseq | -0.2306 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 7.
Survival by SCP2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SCP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SCP2 | 6342 | 3 | 4 | 23 | |
| GSE20123 | SCP2 | 6342 | 3 | 3 | 24 | |
| GSE43470 | SCP2 | 6342 | 6 | 2 | 35 | |
| GSE46452 | SCP2 | 6342 | 2 | 1 | 56 | |
| GSE47630 | SCP2 | 6342 | 8 | 4 | 28 | |
| GSE54993 | SCP2 | 6342 | 0 | 1 | 69 | |
| GSE54994 | SCP2 | 6342 | 11 | 2 | 40 | |
| GSE60625 | SCP2 | 6342 | 0 | 0 | 11 | |
| GSE74703 | SCP2 | 6342 | 4 | 1 | 31 | |
| GSE74704 | SCP2 | 6342 | 2 | 0 | 18 | |
| TCGA | SCP2 | 6342 | 10 | 18 | 68 |
Total number of gains: 49; Total number of losses: 36; Total Number of normals: 403.
Somatic mutations of SCP2:
Generating mutation plots.
Highly correlated genes for SCP2:
Showing top 20/1861 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SCP2 | CA13 | 0.816833 | 3 | 0 | 3 |
| SCP2 | TAB3 | 0.814928 | 7 | 0 | 7 |
| SCP2 | PLEKHA7 | 0.808316 | 7 | 0 | 7 |
| SCP2 | RNF11 | 0.807155 | 12 | 0 | 12 |
| SCP2 | PRKAR2A | 0.806846 | 6 | 0 | 6 |
| SCP2 | TMEM59 | 0.801951 | 12 | 0 | 12 |
| SCP2 | BLNK | 0.800778 | 11 | 0 | 11 |
| SCP2 | KLB | 0.799185 | 6 | 0 | 6 |
| SCP2 | MAGI3 | 0.796624 | 6 | 0 | 6 |
| SCP2 | ZNF823 | 0.792878 | 7 | 0 | 7 |
| SCP2 | CMPK1 | 0.788828 | 13 | 0 | 11 |
| SCP2 | CAPN14 | 0.786367 | 6 | 0 | 6 |
| SCP2 | RAB11A | 0.78596 | 11 | 0 | 11 |
| SCP2 | HPGD | 0.78392 | 11 | 0 | 11 |
| SCP2 | SLC10A5 | 0.781554 | 3 | 0 | 3 |
| SCP2 | RBM20 | 0.78136 | 4 | 0 | 4 |
| SCP2 | VSIG2 | 0.780909 | 6 | 0 | 6 |
| SCP2 | ST6GALNAC1 | 0.780359 | 7 | 0 | 7 |
| SCP2 | TIFA | 0.779401 | 7 | 0 | 7 |
| SCP2 | SFTA2 | 0.779116 | 4 | 0 | 4 |
For details and further investigation, click here
