ZFAND2B

 

Full name: zinc finger AN1-type containing 2B Alias Symbol: AIRAPL
Type: protein-coding gene Cytoband: 2q35
Entrez ID: 130617 HGNC ID: HGNC:25206 Ensembl Gene: ENSG00000158552 OMIM ID: 613474
Drug and gene relationship at DGIdb

 

Expression of ZFAND2B:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ZFAND2B 130617 226168_at -0.7123 0.1704
GSE26886 ZFAND2B 130617 226168_at -1.2474 0.0000
GSE45670 ZFAND2B 130617 226168_at -0.6988 0.0001
GSE53622 ZFAND2B 130617 60190 -0.7823 0.0000
GSE53624 ZFAND2B 130617 60190 -1.0427 0.0000
GSE63941 ZFAND2B 130617 226168_at -0.4872 0.1557
GSE77861 ZFAND2B 130617 226168_at -0.9177 0.0002
GSE97050 ZFAND2B 130617 A_23_P131299 -0.2666 0.2434
SRP007169 ZFAND2B 130617 RNAseq -3.1586 0.0000
SRP008496 ZFAND2B 130617 RNAseq -2.7148 0.0000
SRP064894 ZFAND2B 130617 RNAseq -0.5812 0.0797
SRP133303 ZFAND2B 130617 RNAseq -1.0456 0.0000
SRP159526 ZFAND2B 130617 RNAseq -1.3418 0.0000
SRP193095 ZFAND2B 130617 RNAseq -1.1239 0.0000
SRP219564 ZFAND2B 130617 RNAseq -1.1031 0.0002
TCGA ZFAND2B 130617 RNAseq -0.2066 0.0017

Upregulated datasets: 0; Downregulated datasets: 8.  

 

Survival by ZFAND2B expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of ZFAND2B:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ZFAND2B 130617 2 14 14
GSE20123 ZFAND2B 130617 2 13 15
GSE43470 ZFAND2B 130617 1 7 35
GSE46452 ZFAND2B 130617 0 5 54
GSE47630 ZFAND2B 130617 4 5 31
GSE54993 ZFAND2B 130617 1 2 67
GSE54994 ZFAND2B 130617 8 9 36
GSE60625 ZFAND2B 130617 0 3 8
GSE74703 ZFAND2B 130617 1 5 30
GSE74704 ZFAND2B 130617 2 7 11
TCGA ZFAND2B 130617 12 26 58

Total number of gains: 33; Total number of losses: 96; Total Number of normals: 359.  

 

Somatic mutations of ZFAND2B:

 

Generating mutation plots.

 

Highly correlated genes for ZFAND2B:

 

Showing top 20/1602 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ZFAND2BSFTA20.845781404
ZFAND2BC5orf66-AS10.839088606
ZFAND2BTEKT50.823583404
ZFAND2BCNPPD10.815543707
ZFAND2BSMIM50.809415606
ZFAND2BEHD30.799492707
ZFAND2BBARX20.799225707
ZFAND2BPLEKHA70.795078707
ZFAND2BSLC16A60.794954707
ZFAND2BPHACTR40.794071707
ZFAND2BNAPA0.790885707
ZFAND2BNCK20.790523707
ZFAND2BHEBP20.789706707
ZFAND2BPPP1R70.788346707
ZFAND2BDHRS10.787767606
ZFAND2BCYSRT10.786711606
ZFAND2BBLNK0.786273707
ZFAND2BGYS20.78595606
ZFAND2BCCDC60.785713707
ZFAND2BPPDPF0.785653606

For details and further investigation, click here