NAB1

 

Full name: NGFI-A binding protein 1 Alias Symbol: 
Type: protein-coding gene Cytoband: 2q32.2
Entrez ID: 4664 HGNC ID: HGNC:7626 Ensembl Gene: ENSG00000138386 OMIM ID: 600800
Drug and gene relationship at DGIdb

 

Expression of NAB1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 NAB1 4664 209272_at 0.5321 0.3990
GSE20347 NAB1 4664 209272_at 0.0497 0.8140
GSE23400 NAB1 4664 209272_at 0.2985 0.0085
GSE26886 NAB1 4664 209272_at 0.1622 0.2395
GSE29001 NAB1 4664 209272_at 0.2889 0.3164
GSE38129 NAB1 4664 209272_at 0.2108 0.1569
GSE45670 NAB1 4664 209272_at 0.3092 0.0681
GSE53622 NAB1 4664 22232 0.4319 0.0000
GSE53624 NAB1 4664 22232 0.5923 0.0000
GSE63941 NAB1 4664 209272_at 0.6785 0.2087
GSE77861 NAB1 4664 209272_at 0.2140 0.4610
GSE97050 NAB1 4664 A_23_P209805 0.3614 0.4389
SRP007169 NAB1 4664 RNAseq 0.2890 0.5186
SRP008496 NAB1 4664 RNAseq 0.1675 0.4931
SRP064894 NAB1 4664 RNAseq 0.1558 0.5647
SRP133303 NAB1 4664 RNAseq 0.0926 0.6144
SRP159526 NAB1 4664 RNAseq -0.2209 0.0932
SRP193095 NAB1 4664 RNAseq -0.1393 0.3228
SRP219564 NAB1 4664 RNAseq 0.3257 0.3360
TCGA NAB1 4664 RNAseq 0.0863 0.0886

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by NAB1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of NAB1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 NAB1 4664 8 2 20
GSE20123 NAB1 4664 8 2 20
GSE43470 NAB1 4664 3 1 39
GSE46452 NAB1 4664 1 4 54
GSE47630 NAB1 4664 4 5 31
GSE54993 NAB1 4664 0 5 65
GSE54994 NAB1 4664 12 6 35
GSE60625 NAB1 4664 0 3 8
GSE74703 NAB1 4664 2 1 33
GSE74704 NAB1 4664 3 2 15
TCGA NAB1 4664 25 7 64

Total number of gains: 66; Total number of losses: 38; Total Number of normals: 384.  


 

Somatic mutations of NAB1:

 

Generating mutation plots.

 

Highly correlated genes for NAB1:

 

Showing top 20/385 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
NAB1NNT0.784872303
NAB1NUP540.750807303
NAB1RTN4R0.728581303
NAB1MRPL420.715265303
NAB1CEP630.713312303
NAB1SESN30.703229303
NAB1GPD20.701536303
NAB1CSTF2T0.698953303
NAB1RPRD1A0.694666303
NAB1ZC3H12C0.689795303
NAB1NCEH10.685864303
NAB1TDRP0.683177303
NAB1PDHX0.681894403
NAB1TYW50.676604303
NAB1GMPR20.670229303
NAB1PHOSPHO20.667535303
NAB1NFKB10.666367303
NAB1SAAL10.661773403
NAB1RMND10.658722303
NAB1SUPT7L0.654419503

For details and further investigation, click here