MRPL42

 

Full name: mitochondrial ribosomal protein L42 Alias Symbol: MRPS32|MRP-L31|RPML31|PTD007|HSPC204|MRPL31
Type: protein-coding gene Cytoband: 12q22
Entrez ID: 28977 HGNC ID: HGNC:14493 Ensembl Gene: ENSG00000198015 OMIM ID: 611847
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of MRPL42:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 MRPL42 28977 217919_s_at 0.3477 0.3485
GSE20347 MRPL42 28977 217919_s_at 0.8431 0.0001
GSE23400 MRPL42 28977 217919_s_at 0.6477 0.0000
GSE26886 MRPL42 28977 222466_s_at -0.3778 0.1836
GSE29001 MRPL42 28977 217919_s_at 0.6434 0.1257
GSE38129 MRPL42 28977 217919_s_at 0.9464 0.0000
GSE45670 MRPL42 28977 217919_s_at 0.5867 0.0002
GSE53622 MRPL42 28977 607 -0.0322 0.6640
GSE53624 MRPL42 28977 52197 0.3240 0.0000
GSE63941 MRPL42 28977 217919_s_at 1.8181 0.0002
GSE77861 MRPL42 28977 217919_s_at 0.2163 0.5654
GSE97050 MRPL42 28977 A_24_P352445 -0.1060 0.6539
SRP007169 MRPL42 28977 RNAseq 0.0765 0.8254
SRP008496 MRPL42 28977 RNAseq 0.1630 0.4793
SRP064894 MRPL42 28977 RNAseq 0.1226 0.3686
SRP133303 MRPL42 28977 RNAseq 0.2063 0.1710
SRP159526 MRPL42 28977 RNAseq 0.1719 0.4210
SRP193095 MRPL42 28977 RNAseq -0.0498 0.4580
SRP219564 MRPL42 28977 RNAseq 0.0731 0.7232
TCGA MRPL42 28977 RNAseq 0.0795 0.1251

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by MRPL42 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of MRPL42:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 MRPL42 28977 3 2 25
GSE20123 MRPL42 28977 3 2 25
GSE43470 MRPL42 28977 3 0 40
GSE46452 MRPL42 28977 9 1 49
GSE47630 MRPL42 28977 10 1 29
GSE54993 MRPL42 28977 0 5 65
GSE54994 MRPL42 28977 5 1 47
GSE60625 MRPL42 28977 0 0 11
GSE74703 MRPL42 28977 3 0 33
GSE74704 MRPL42 28977 1 2 17
TCGA MRPL42 28977 17 11 68

Total number of gains: 54; Total number of losses: 25; Total Number of normals: 409.  

 

Somatic mutations of MRPL42:

 

Generating mutation plots.

 

Highly correlated genes for MRPL42:

 

Showing top 20/1195 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
MRPL42MRRF0.838263303
MRPL42CNOT100.802709303
MRPL42ALG100.777154404
MRPL42NUP370.773068909
MRPL42ELOF10.767266303
MRPL42TIA10.761895303
MRPL42EARS20.751652303
MRPL42AURKB0.751037707
MRPL42NDC10.751006807
MRPL42IFT800.750856303
MRPL42ATP6V0A20.750535505
MRPL42MITD10.747225303
MRPL42RNF144B0.745476303
MRPL42NOL110.7402821008
MRPL42C12orf450.736471404
MRPL42SMC20.735329909
MRPL42GART0.732201808
MRPL42WIPF20.729679303
MRPL42XPOT0.726617808
MRPL42TPX20.726195807

For details and further investigation, click here