| Full name: regulation of nuclear pre-mRNA domain containing 1A | Alias Symbol: P15RS|FLJ10656|HsT3101 | ||
| Type: protein-coding gene | Cytoband: 18q12.2 | ||
| Entrez ID: 55197 | HGNC ID: HGNC:25560 | Ensembl Gene: ENSG00000141425 | OMIM ID: 610347 |
| Drug and gene relationship at DGIdb | |||
Expression of RPRD1A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RPRD1A | 55197 | 225953_at | -0.1061 | 0.8253 | |
| GSE20347 | RPRD1A | 55197 | 218209_s_at | 0.0579 | 0.8469 | |
| GSE23400 | RPRD1A | 55197 | 218209_s_at | 0.1024 | 0.2531 | |
| GSE26886 | RPRD1A | 55197 | 225953_at | -0.1410 | 0.5797 | |
| GSE29001 | RPRD1A | 55197 | 218209_s_at | 0.1114 | 0.7706 | |
| GSE38129 | RPRD1A | 55197 | 218209_s_at | 0.2711 | 0.1877 | |
| GSE45670 | RPRD1A | 55197 | 225953_at | -0.0895 | 0.6233 | |
| GSE53622 | RPRD1A | 55197 | 49596 | 0.0254 | 0.8156 | |
| GSE53624 | RPRD1A | 55197 | 23060 | -0.0953 | 0.2559 | |
| GSE63941 | RPRD1A | 55197 | 225953_at | -0.2474 | 0.7065 | |
| GSE77861 | RPRD1A | 55197 | 225953_at | 0.3672 | 0.2261 | |
| GSE97050 | RPRD1A | 55197 | A_33_P3291349 | -0.2077 | 0.6270 | |
| SRP007169 | RPRD1A | 55197 | RNAseq | 0.9342 | 0.0520 | |
| SRP008496 | RPRD1A | 55197 | RNAseq | 1.4710 | 0.0002 | |
| SRP064894 | RPRD1A | 55197 | RNAseq | -0.0965 | 0.5249 | |
| SRP133303 | RPRD1A | 55197 | RNAseq | 0.1293 | 0.5373 | |
| SRP159526 | RPRD1A | 55197 | RNAseq | 0.1723 | 0.5153 | |
| SRP193095 | RPRD1A | 55197 | RNAseq | 0.0447 | 0.6515 | |
| SRP219564 | RPRD1A | 55197 | RNAseq | -0.3283 | 0.3381 | |
| TCGA | RPRD1A | 55197 | RNAseq | -0.0843 | 0.1663 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by RPRD1A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RPRD1A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RPRD1A | 55197 | 2 | 5 | 23 | |
| GSE20123 | RPRD1A | 55197 | 2 | 5 | 23 | |
| GSE43470 | RPRD1A | 55197 | 0 | 3 | 40 | |
| GSE46452 | RPRD1A | 55197 | 1 | 25 | 33 | |
| GSE47630 | RPRD1A | 55197 | 5 | 20 | 15 | |
| GSE54993 | RPRD1A | 55197 | 8 | 1 | 61 | |
| GSE54994 | RPRD1A | 55197 | 1 | 16 | 36 | |
| GSE60625 | RPRD1A | 55197 | 0 | 4 | 7 | |
| GSE74703 | RPRD1A | 55197 | 0 | 3 | 33 | |
| GSE74704 | RPRD1A | 55197 | 1 | 4 | 15 | |
| TCGA | RPRD1A | 55197 | 16 | 39 | 41 |
Total number of gains: 36; Total number of losses: 125; Total Number of normals: 327.
Somatic mutations of RPRD1A:
Generating mutation plots.
Highly correlated genes for RPRD1A:
Showing top 20/198 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RPRD1A | NLK | 0.724599 | 3 | 0 | 3 |
| RPRD1A | THUMPD1 | 0.721821 | 3 | 0 | 3 |
| RPRD1A | COPS8 | 0.717037 | 3 | 0 | 3 |
| RPRD1A | TRMT61B | 0.704718 | 3 | 0 | 3 |
| RPRD1A | ZNF208 | 0.697814 | 3 | 0 | 3 |
| RPRD1A | NAB1 | 0.694666 | 3 | 0 | 3 |
| RPRD1A | MSI2 | 0.694042 | 3 | 0 | 3 |
| RPRD1A | LUC7L3 | 0.692707 | 3 | 0 | 3 |
| RPRD1A | C1orf54 | 0.692354 | 3 | 0 | 3 |
| RPRD1A | SLC25A46 | 0.689824 | 3 | 0 | 3 |
| RPRD1A | APIP | 0.6867 | 4 | 0 | 3 |
| RPRD1A | COL15A1 | 0.681467 | 3 | 0 | 3 |
| RPRD1A | OLFML1 | 0.68069 | 3 | 0 | 3 |
| RPRD1A | NME4 | 0.676103 | 4 | 0 | 3 |
| RPRD1A | GEMIN6 | 0.675164 | 3 | 0 | 3 |
| RPRD1A | HEXB | 0.667549 | 3 | 0 | 3 |
| RPRD1A | MKLN1 | 0.667472 | 5 | 0 | 5 |
| RPRD1A | GNB5 | 0.664771 | 3 | 0 | 3 |
| RPRD1A | FNIP2 | 0.664556 | 3 | 0 | 3 |
| RPRD1A | TMX3 | 0.66341 | 4 | 0 | 3 |
For details and further investigation, click here
