| Full name: phosphatase, orphan 2 | Alias Symbol: MGC22679 | ||
| Type: protein-coding gene | Cytoband: 2q31.1 | ||
| Entrez ID: 493911 | HGNC ID: HGNC:28316 | Ensembl Gene: ENSG00000144362 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of PHOSPHO2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PHOSPHO2 | 493911 | 230434_at | 0.2199 | 0.6860 | |
| GSE26886 | PHOSPHO2 | 493911 | 230434_at | 0.1927 | 0.7530 | |
| GSE45670 | PHOSPHO2 | 493911 | 230434_at | 0.1356 | 0.7203 | |
| GSE53622 | PHOSPHO2 | 493911 | 21888 | 0.0486 | 0.6940 | |
| GSE53624 | PHOSPHO2 | 493911 | 21888 | 0.2384 | 0.0272 | |
| GSE63941 | PHOSPHO2 | 493911 | 230434_at | -0.3685 | 0.4603 | |
| GSE77861 | PHOSPHO2 | 493911 | 230434_at | 0.5256 | 0.0278 | |
| GSE97050 | PHOSPHO2 | 493911 | A_23_P165788 | 0.0387 | 0.8998 | |
| SRP007169 | PHOSPHO2 | 493911 | RNAseq | 0.6199 | 0.4032 | |
| SRP064894 | PHOSPHO2 | 493911 | RNAseq | -0.0489 | 0.8143 | |
| SRP133303 | PHOSPHO2 | 493911 | RNAseq | -0.0673 | 0.7628 | |
| SRP159526 | PHOSPHO2 | 493911 | RNAseq | 0.6398 | 0.2226 | |
| SRP193095 | PHOSPHO2 | 493911 | RNAseq | 0.1023 | 0.5027 | |
| SRP219564 | PHOSPHO2 | 493911 | RNAseq | 0.3957 | 0.4785 | |
| TCGA | PHOSPHO2 | 493911 | RNAseq | -0.2571 | 0.0260 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PHOSPHO2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PHOSPHO2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PHOSPHO2 | 493911 | 8 | 0 | 22 | |
| GSE20123 | PHOSPHO2 | 493911 | 8 | 0 | 22 | |
| GSE43470 | PHOSPHO2 | 493911 | 4 | 1 | 38 | |
| GSE46452 | PHOSPHO2 | 493911 | 1 | 4 | 54 | |
| GSE47630 | PHOSPHO2 | 493911 | 5 | 3 | 32 | |
| GSE54993 | PHOSPHO2 | 493911 | 0 | 5 | 65 | |
| GSE54994 | PHOSPHO2 | 493911 | 11 | 3 | 39 | |
| GSE60625 | PHOSPHO2 | 493911 | 0 | 3 | 8 | |
| GSE74703 | PHOSPHO2 | 493911 | 3 | 1 | 32 | |
| GSE74704 | PHOSPHO2 | 493911 | 5 | 0 | 15 | |
| TCGA | PHOSPHO2 | 493911 | 24 | 10 | 62 |
Total number of gains: 69; Total number of losses: 30; Total Number of normals: 389.
Somatic mutations of PHOSPHO2:
Generating mutation plots.
Highly correlated genes for PHOSPHO2:
Showing top 20/418 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PHOSPHO2 | TTC21B | 0.795391 | 3 | 0 | 3 |
| PHOSPHO2 | MRPL50 | 0.781677 | 3 | 0 | 3 |
| PHOSPHO2 | CELF1 | 0.768442 | 3 | 0 | 3 |
| PHOSPHO2 | DHRSX | 0.756719 | 3 | 0 | 3 |
| PHOSPHO2 | PWP1 | 0.736287 | 3 | 0 | 3 |
| PHOSPHO2 | SAFB2 | 0.732924 | 3 | 0 | 3 |
| PHOSPHO2 | IFNGR1 | 0.732113 | 3 | 0 | 3 |
| PHOSPHO2 | DNASE2 | 0.728658 | 3 | 0 | 3 |
| PHOSPHO2 | PARP14 | 0.726797 | 3 | 0 | 3 |
| PHOSPHO2 | STK3 | 0.726267 | 3 | 0 | 3 |
| PHOSPHO2 | RAD21 | 0.725709 | 3 | 0 | 3 |
| PHOSPHO2 | ALKBH6 | 0.725602 | 3 | 0 | 3 |
| PHOSPHO2 | CLP1 | 0.723548 | 3 | 0 | 3 |
| PHOSPHO2 | NENF | 0.721116 | 3 | 0 | 3 |
| PHOSPHO2 | FAM161B | 0.718601 | 3 | 0 | 3 |
| PHOSPHO2 | CBFA2T2 | 0.710744 | 3 | 0 | 3 |
| PHOSPHO2 | PTK2 | 0.710032 | 3 | 0 | 3 |
| PHOSPHO2 | CHIC1 | 0.708992 | 3 | 0 | 3 |
| PHOSPHO2 | CCDC150 | 0.707484 | 3 | 0 | 3 |
| PHOSPHO2 | STAMBPL1 | 0.70532 | 3 | 0 | 3 |
For details and further investigation, click here
