| Full name: glycerol-3-phosphate dehydrogenase 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 2q24.1 | ||
| Entrez ID: 2820 | HGNC ID: HGNC:4456 | Ensembl Gene: ENSG00000115159 | OMIM ID: 138430 |
| Drug and gene relationship at DGIdb | |||
Expression of GPD2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GPD2 | 2820 | 225447_at | 0.6801 | 0.3174 | |
| GSE20347 | GPD2 | 2820 | 210007_s_at | -0.4668 | 0.0008 | |
| GSE23400 | GPD2 | 2820 | 210007_s_at | -0.2443 | 0.0027 | |
| GSE26886 | GPD2 | 2820 | 225447_at | -1.0283 | 0.0006 | |
| GSE29001 | GPD2 | 2820 | 210007_s_at | -0.6269 | 0.0610 | |
| GSE38129 | GPD2 | 2820 | 210007_s_at | 0.1587 | 0.5645 | |
| GSE45670 | GPD2 | 2820 | 225447_at | 0.2269 | 0.2885 | |
| GSE53622 | GPD2 | 2820 | 82046 | 0.0662 | 0.5590 | |
| GSE53624 | GPD2 | 2820 | 82046 | -0.1807 | 0.0325 | |
| GSE63941 | GPD2 | 2820 | 225447_at | -0.1907 | 0.8904 | |
| GSE77861 | GPD2 | 2820 | 225447_at | 0.2406 | 0.5387 | |
| GSE97050 | GPD2 | 2820 | A_33_P3354564 | 0.3315 | 0.4649 | |
| SRP007169 | GPD2 | 2820 | RNAseq | -0.5785 | 0.1177 | |
| SRP008496 | GPD2 | 2820 | RNAseq | -0.7450 | 0.0024 | |
| SRP064894 | GPD2 | 2820 | RNAseq | -0.4714 | 0.0716 | |
| SRP133303 | GPD2 | 2820 | RNAseq | 0.2948 | 0.3510 | |
| SRP159526 | GPD2 | 2820 | RNAseq | -0.0903 | 0.7617 | |
| SRP193095 | GPD2 | 2820 | RNAseq | -0.5249 | 0.0004 | |
| SRP219564 | GPD2 | 2820 | RNAseq | -0.4438 | 0.4348 | |
| TCGA | GPD2 | 2820 | RNAseq | 0.1291 | 0.0379 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by GPD2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GPD2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GPD2 | 2820 | 4 | 1 | 25 | |
| GSE20123 | GPD2 | 2820 | 4 | 1 | 25 | |
| GSE43470 | GPD2 | 2820 | 4 | 1 | 38 | |
| GSE46452 | GPD2 | 2820 | 1 | 4 | 54 | |
| GSE47630 | GPD2 | 2820 | 5 | 3 | 32 | |
| GSE54993 | GPD2 | 2820 | 0 | 4 | 66 | |
| GSE54994 | GPD2 | 2820 | 11 | 2 | 40 | |
| GSE60625 | GPD2 | 2820 | 0 | 3 | 8 | |
| GSE74703 | GPD2 | 2820 | 3 | 1 | 32 | |
| GSE74704 | GPD2 | 2820 | 3 | 0 | 17 | |
| TCGA | GPD2 | 2820 | 21 | 9 | 66 |
Total number of gains: 56; Total number of losses: 29; Total Number of normals: 403.
Somatic mutations of GPD2:
Generating mutation plots.
Highly correlated genes for GPD2:
Showing top 20/624 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GPD2 | TRUB1 | 0.794 | 3 | 0 | 3 |
| GPD2 | SMC2 | 0.792477 | 3 | 0 | 3 |
| GPD2 | MAP4K4 | 0.784701 | 3 | 0 | 3 |
| GPD2 | TMEM167A | 0.761583 | 3 | 0 | 3 |
| GPD2 | EAF1 | 0.758532 | 3 | 0 | 3 |
| GPD2 | SNX17 | 0.75053 | 3 | 0 | 3 |
| GPD2 | TMEM54 | 0.749558 | 3 | 0 | 3 |
| GPD2 | SLC30A9 | 0.747007 | 4 | 0 | 4 |
| GPD2 | TBRG1 | 0.745961 | 3 | 0 | 3 |
| GPD2 | NUS1 | 0.744353 | 3 | 0 | 3 |
| GPD2 | NECAP1 | 0.742152 | 3 | 0 | 3 |
| GPD2 | FUCA1 | 0.741506 | 3 | 0 | 3 |
| GPD2 | SACM1L | 0.731947 | 4 | 0 | 4 |
| GPD2 | UBE2J1 | 0.728587 | 4 | 0 | 4 |
| GPD2 | MRPL48 | 0.727523 | 3 | 0 | 3 |
| GPD2 | TMTC3 | 0.72549 | 4 | 0 | 3 |
| GPD2 | RAB22A | 0.725371 | 5 | 0 | 5 |
| GPD2 | ZNF607 | 0.722511 | 3 | 0 | 3 |
| GPD2 | TMEM181 | 0.717729 | 3 | 0 | 3 |
| GPD2 | MRPS33 | 0.717546 | 3 | 0 | 3 |
For details and further investigation, click here
