| Full name: nucleoporin 54 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 4q21.1 | ||
| Entrez ID: 53371 | HGNC ID: HGNC:17359 | Ensembl Gene: ENSG00000138750 | OMIM ID: 607607 |
| Drug and gene relationship at DGIdb | |||
Expression of NUP54:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NUP54 | 53371 | 218256_s_at | 0.2080 | 0.6053 | |
| GSE20347 | NUP54 | 53371 | 218256_s_at | 0.2075 | 0.2471 | |
| GSE23400 | NUP54 | 53371 | 218256_s_at | 0.2971 | 0.0002 | |
| GSE26886 | NUP54 | 53371 | 218256_s_at | 0.3781 | 0.1270 | |
| GSE29001 | NUP54 | 53371 | 218256_s_at | 0.2076 | 0.6143 | |
| GSE38129 | NUP54 | 53371 | 218256_s_at | 0.2372 | 0.0600 | |
| GSE45670 | NUP54 | 53371 | 218256_s_at | -0.0209 | 0.9088 | |
| GSE53622 | NUP54 | 53371 | 10469 | 0.2856 | 0.0007 | |
| GSE53624 | NUP54 | 53371 | 10469 | 0.2945 | 0.0085 | |
| GSE63941 | NUP54 | 53371 | 218256_s_at | 0.2619 | 0.4815 | |
| GSE77861 | NUP54 | 53371 | 218256_s_at | -0.0328 | 0.9310 | |
| GSE97050 | NUP54 | 53371 | A_23_P92320 | 0.2804 | 0.3987 | |
| SRP007169 | NUP54 | 53371 | RNAseq | 0.0942 | 0.8387 | |
| SRP008496 | NUP54 | 53371 | RNAseq | 0.2714 | 0.3060 | |
| SRP064894 | NUP54 | 53371 | RNAseq | -0.0454 | 0.7422 | |
| SRP133303 | NUP54 | 53371 | RNAseq | 0.3314 | 0.1143 | |
| SRP159526 | NUP54 | 53371 | RNAseq | 0.1175 | 0.6723 | |
| SRP193095 | NUP54 | 53371 | RNAseq | -0.1039 | 0.3414 | |
| SRP219564 | NUP54 | 53371 | RNAseq | -0.1116 | 0.4772 | |
| TCGA | NUP54 | 53371 | RNAseq | 0.0897 | 0.0794 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NUP54 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NUP54:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NUP54 | 53371 | 2 | 9 | 19 | |
| GSE20123 | NUP54 | 53371 | 2 | 9 | 19 | |
| GSE43470 | NUP54 | 53371 | 0 | 13 | 30 | |
| GSE46452 | NUP54 | 53371 | 1 | 36 | 22 | |
| GSE47630 | NUP54 | 53371 | 1 | 19 | 20 | |
| GSE54993 | NUP54 | 53371 | 7 | 0 | 63 | |
| GSE54994 | NUP54 | 53371 | 0 | 9 | 44 | |
| GSE60625 | NUP54 | 53371 | 0 | 0 | 11 | |
| GSE74703 | NUP54 | 53371 | 0 | 11 | 25 | |
| GSE74704 | NUP54 | 53371 | 2 | 5 | 13 | |
| TCGA | NUP54 | 53371 | 17 | 30 | 49 |
Total number of gains: 32; Total number of losses: 141; Total Number of normals: 315.
Somatic mutations of NUP54:
Generating mutation plots.
Highly correlated genes for NUP54:
Showing top 20/790 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NUP54 | NPAT | 0.794138 | 3 | 0 | 3 |
| NUP54 | RBM7 | 0.787074 | 3 | 0 | 3 |
| NUP54 | MTOR | 0.774994 | 3 | 0 | 3 |
| NUP54 | STAU1 | 0.763278 | 3 | 0 | 3 |
| NUP54 | TTC37 | 0.754276 | 3 | 0 | 3 |
| NUP54 | VPS33A | 0.751988 | 3 | 0 | 3 |
| NUP54 | MDM2 | 0.751116 | 4 | 0 | 4 |
| NUP54 | NAB1 | 0.750807 | 3 | 0 | 3 |
| NUP54 | ABCB10 | 0.750144 | 4 | 0 | 4 |
| NUP54 | TBC1D15 | 0.748026 | 4 | 0 | 4 |
| NUP54 | SNX30 | 0.743031 | 3 | 0 | 3 |
| NUP54 | ARFGEF2 | 0.737991 | 4 | 0 | 3 |
| NUP54 | UBA3 | 0.731175 | 3 | 0 | 3 |
| NUP54 | TUBGCP3 | 0.726998 | 3 | 0 | 3 |
| NUP54 | MCPH1 | 0.722319 | 3 | 0 | 3 |
| NUP54 | AEBP2 | 0.720915 | 3 | 0 | 3 |
| NUP54 | RNF2 | 0.720039 | 3 | 0 | 3 |
| NUP54 | HCCS | 0.719729 | 4 | 0 | 3 |
| NUP54 | KDM5B | 0.716147 | 3 | 0 | 3 |
| NUP54 | NOA1 | 0.710133 | 4 | 0 | 3 |
For details and further investigation, click here
