| Full name: neutral cholesterol ester hydrolase 1 | Alias Symbol: KIAA1363|NCEH | ||
| Type: protein-coding gene | Cytoband: 3q26.31 | ||
| Entrez ID: 57552 | HGNC ID: HGNC:29260 | Ensembl Gene: ENSG00000144959 | OMIM ID: 613234 |
| Drug and gene relationship at DGIdb | |||
Expression of NCEH1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NCEH1 | 57552 | 225847_at | 0.9494 | 0.2394 | |
| GSE26886 | NCEH1 | 57552 | 225847_at | 0.0148 | 0.9823 | |
| GSE45670 | NCEH1 | 57552 | 225847_at | 1.0668 | 0.0062 | |
| GSE53622 | NCEH1 | 57552 | 116847 | 0.4241 | 0.0012 | |
| GSE53624 | NCEH1 | 57552 | 116847 | 0.5071 | 0.0000 | |
| GSE63941 | NCEH1 | 57552 | 225847_at | -0.4133 | 0.6880 | |
| GSE77861 | NCEH1 | 57552 | 225847_at | 0.2495 | 0.7670 | |
| GSE97050 | NCEH1 | 57552 | A_23_P132644 | 0.8063 | 0.2873 | |
| SRP007169 | NCEH1 | 57552 | RNAseq | 0.8917 | 0.0624 | |
| SRP008496 | NCEH1 | 57552 | RNAseq | 0.8916 | 0.0330 | |
| SRP064894 | NCEH1 | 57552 | RNAseq | 0.7650 | 0.0221 | |
| SRP133303 | NCEH1 | 57552 | RNAseq | 1.0234 | 0.0013 | |
| SRP159526 | NCEH1 | 57552 | RNAseq | 1.0438 | 0.0946 | |
| SRP193095 | NCEH1 | 57552 | RNAseq | 0.5202 | 0.0395 | |
| SRP219564 | NCEH1 | 57552 | RNAseq | 1.0499 | 0.1772 | |
| TCGA | NCEH1 | 57552 | RNAseq | -0.0077 | 0.9399 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by NCEH1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NCEH1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NCEH1 | 57552 | 24 | 0 | 6 | |
| GSE20123 | NCEH1 | 57552 | 24 | 0 | 6 | |
| GSE43470 | NCEH1 | 57552 | 23 | 0 | 20 | |
| GSE46452 | NCEH1 | 57552 | 19 | 1 | 39 | |
| GSE47630 | NCEH1 | 57552 | 27 | 2 | 11 | |
| GSE54993 | NCEH1 | 57552 | 1 | 15 | 54 | |
| GSE54994 | NCEH1 | 57552 | 41 | 0 | 12 | |
| GSE60625 | NCEH1 | 57552 | 0 | 6 | 5 | |
| GSE74703 | NCEH1 | 57552 | 19 | 0 | 17 | |
| GSE74704 | NCEH1 | 57552 | 16 | 0 | 4 | |
| TCGA | NCEH1 | 57552 | 80 | 0 | 16 |
Total number of gains: 274; Total number of losses: 24; Total Number of normals: 190.
Somatic mutations of NCEH1:
Generating mutation plots.
Highly correlated genes for NCEH1:
Showing top 20/154 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NCEH1 | LRIF1 | 0.772729 | 3 | 0 | 3 |
| NCEH1 | SMC4 | 0.721837 | 3 | 0 | 3 |
| NCEH1 | CLDN1 | 0.72152 | 3 | 0 | 3 |
| NCEH1 | HPS4 | 0.706247 | 3 | 0 | 3 |
| NCEH1 | TNIP3 | 0.704542 | 3 | 0 | 3 |
| NCEH1 | EIF2A | 0.698112 | 3 | 0 | 3 |
| NCEH1 | GSK3B | 0.698008 | 3 | 0 | 3 |
| NCEH1 | NAB1 | 0.685864 | 3 | 0 | 3 |
| NCEH1 | SAAL1 | 0.680739 | 3 | 0 | 3 |
| NCEH1 | FBXO11 | 0.675437 | 3 | 0 | 3 |
| NCEH1 | SMC2 | 0.671861 | 3 | 0 | 3 |
| NCEH1 | TMTC3 | 0.671688 | 3 | 0 | 3 |
| NCEH1 | SIPA1 | 0.665766 | 3 | 0 | 3 |
| NCEH1 | TMEM150C | 0.661994 | 3 | 0 | 3 |
| NCEH1 | GPD2 | 0.661409 | 5 | 0 | 3 |
| NCEH1 | STAG1 | 0.661081 | 3 | 0 | 3 |
| NCEH1 | SRPRB | 0.657708 | 4 | 0 | 3 |
| NCEH1 | GK5 | 0.653613 | 3 | 0 | 3 |
| NCEH1 | PAPOLG | 0.653076 | 3 | 0 | 3 |
| NCEH1 | CHEK1 | 0.651076 | 4 | 0 | 3 |
For details and further investigation, click here
