SUPT7L

 

Full name: SPT7 like, STAGA complex gamma subunit Alias Symbol: STAF65gamma|KIAA0764|SPT7L|STAF65
Type: protein-coding gene Cytoband: 2p23.3
Entrez ID: 9913 HGNC ID: HGNC:30632 Ensembl Gene: ENSG00000119760 OMIM ID: 612762
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of SUPT7L:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SUPT7L 9913 201837_s_at 0.2736 0.5130
GSE20347 SUPT7L 9913 201837_s_at 0.5748 0.0005
GSE23400 SUPT7L 9913 201837_s_at 0.5811 0.0000
GSE26886 SUPT7L 9913 201837_s_at 0.3614 0.0742
GSE29001 SUPT7L 9913 201837_s_at 0.7228 0.0096
GSE38129 SUPT7L 9913 201837_s_at 0.5411 0.0000
GSE45670 SUPT7L 9913 201837_s_at 0.6818 0.0006
GSE53622 SUPT7L 9913 114590 0.2614 0.0001
GSE53624 SUPT7L 9913 114590 0.4423 0.0000
GSE63941 SUPT7L 9913 201837_s_at 0.1532 0.7554
GSE77861 SUPT7L 9913 201837_s_at 0.6296 0.0083
GSE97050 SUPT7L 9913 A_23_P210091 -0.0271 0.9297
SRP007169 SUPT7L 9913 RNAseq 0.9067 0.0315
SRP008496 SUPT7L 9913 RNAseq 1.1846 0.0001
SRP064894 SUPT7L 9913 RNAseq 0.7476 0.0000
SRP133303 SUPT7L 9913 RNAseq 0.2988 0.0019
SRP159526 SUPT7L 9913 RNAseq 0.5126 0.0718
SRP193095 SUPT7L 9913 RNAseq 0.4283 0.0000
SRP219564 SUPT7L 9913 RNAseq 0.3226 0.2683
TCGA SUPT7L 9913 RNAseq 0.0587 0.2208

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by SUPT7L expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of SUPT7L:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SUPT7L 9913 11 2 17
GSE20123 SUPT7L 9913 11 2 17
GSE43470 SUPT7L 9913 3 1 39
GSE46452 SUPT7L 9913 2 4 53
GSE47630 SUPT7L 9913 8 0 32
GSE54993 SUPT7L 9913 0 6 64
GSE54994 SUPT7L 9913 10 0 43
GSE60625 SUPT7L 9913 0 3 8
GSE74703 SUPT7L 9913 3 0 33
GSE74704 SUPT7L 9913 9 1 10
TCGA SUPT7L 9913 36 2 58

Total number of gains: 93; Total number of losses: 21; Total Number of normals: 374.  

 

Somatic mutations of SUPT7L:

 

Generating mutation plots.

 

Highly correlated genes for SUPT7L:

 

Showing top 20/1477 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SUPT7LLINGO10.796407303
SUPT7LTMEM180.780685303
SUPT7LLRRC580.775565303
SUPT7LSPTBN10.771254505
SUPT7LRTKN0.762994404
SUPT7LATXN1L0.757305303
SUPT7LU2SURP0.749638909
SUPT7LSLC6A60.741144303
SUPT7LA4GALT0.738206303
SUPT7LUBXN2A0.735086403
SUPT7LNUP350.730998403
SUPT7LCDC42SE20.730368303
SUPT7LRNPS10.72804606
SUPT7LWDR590.724628404
SUPT7LHIBADH0.724134303
SUPT7LKLHL50.723266403
SUPT7LMRPS50.721414404
SUPT7LSLC7A6OS0.720473403
SUPT7LLCLAT10.719668606
SUPT7LZBTB90.718288303

For details and further investigation, click here