| Full name: reticulon 4 receptor | Alias Symbol: NOGOR | ||
| Type: protein-coding gene | Cytoband: 22q11.21 | ||
| Entrez ID: 65078 | HGNC ID: HGNC:18601 | Ensembl Gene: ENSG00000040608 | OMIM ID: 605566 |
| Drug and gene relationship at DGIdb | |||
Expression of RTN4R:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RTN4R | 65078 | 228550_at | 0.5732 | 0.1793 | |
| GSE26886 | RTN4R | 65078 | 228550_at | 0.4857 | 0.0129 | |
| GSE45670 | RTN4R | 65078 | 228550_at | 0.4245 | 0.0103 | |
| GSE53622 | RTN4R | 65078 | 3820 | 1.4225 | 0.0000 | |
| GSE53624 | RTN4R | 65078 | 3820 | 1.5358 | 0.0000 | |
| GSE63941 | RTN4R | 65078 | 228550_at | 1.1392 | 0.0677 | |
| GSE77861 | RTN4R | 65078 | 228550_at | 0.2413 | 0.2175 | |
| GSE97050 | RTN4R | 65078 | A_23_P132175 | 0.2556 | 0.3440 | |
| SRP007169 | RTN4R | 65078 | RNAseq | 1.1952 | 0.0927 | |
| SRP008496 | RTN4R | 65078 | RNAseq | 0.8171 | 0.0532 | |
| SRP133303 | RTN4R | 65078 | RNAseq | 1.8044 | 0.0001 | |
| SRP159526 | RTN4R | 65078 | RNAseq | 2.2231 | 0.0000 | |
| SRP219564 | RTN4R | 65078 | RNAseq | 2.2799 | 0.0001 | |
| TCGA | RTN4R | 65078 | RNAseq | 0.9154 | 0.0000 |
Upregulated datasets: 5; Downregulated datasets: 0.
Survival by RTN4R expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RTN4R:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RTN4R | 65078 | 5 | 7 | 18 | |
| GSE20123 | RTN4R | 65078 | 5 | 7 | 18 | |
| GSE43470 | RTN4R | 65078 | 4 | 7 | 32 | |
| GSE46452 | RTN4R | 65078 | 33 | 1 | 25 | |
| GSE47630 | RTN4R | 65078 | 8 | 5 | 27 | |
| GSE54993 | RTN4R | 65078 | 3 | 6 | 61 | |
| GSE54994 | RTN4R | 65078 | 12 | 7 | 34 | |
| GSE60625 | RTN4R | 65078 | 5 | 0 | 6 | |
| GSE74703 | RTN4R | 65078 | 4 | 5 | 27 | |
| GSE74704 | RTN4R | 65078 | 3 | 4 | 13 | |
| TCGA | RTN4R | 65078 | 27 | 17 | 52 |
Total number of gains: 109; Total number of losses: 66; Total Number of normals: 313.
Somatic mutations of RTN4R:
Generating mutation plots.
Highly correlated genes for RTN4R:
Showing top 20/1238 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RTN4R | TNFRSF1A | 0.786891 | 4 | 0 | 4 |
| RTN4R | FSIP2 | 0.762215 | 3 | 0 | 3 |
| RTN4R | SLC39A3 | 0.738493 | 3 | 0 | 3 |
| RTN4R | IAH1 | 0.733068 | 3 | 0 | 3 |
| RTN4R | NIPA2 | 0.72982 | 3 | 0 | 3 |
| RTN4R | NAB1 | 0.728581 | 3 | 0 | 3 |
| RTN4R | FOXRED2 | 0.717687 | 4 | 0 | 4 |
| RTN4R | SLC25A1 | 0.71757 | 7 | 0 | 6 |
| RTN4R | SPON2 | 0.71545 | 3 | 0 | 3 |
| RTN4R | ALG12 | 0.714054 | 4 | 0 | 4 |
| RTN4R | FAM89A | 0.713535 | 3 | 0 | 3 |
| RTN4R | SLC44A1 | 0.711135 | 5 | 0 | 5 |
| RTN4R | HPS4 | 0.70561 | 3 | 0 | 3 |
| RTN4R | LDB1 | 0.705578 | 4 | 0 | 3 |
| RTN4R | EIF4G1 | 0.700672 | 4 | 0 | 4 |
| RTN4R | GTF2H3 | 0.699731 | 3 | 0 | 3 |
| RTN4R | DEPDC1 | 0.694781 | 5 | 0 | 5 |
| RTN4R | CEP55 | 0.694338 | 5 | 0 | 5 |
| RTN4R | NT5DC2 | 0.693245 | 3 | 0 | 3 |
| RTN4R | UCK2 | 0.692678 | 3 | 0 | 3 |
For details and further investigation, click here
