REEP2

 

Full name: receptor accessory protein 2 Alias Symbol: SGC32445|SPG72|Yip2d
Type: protein-coding gene Cytoband: 5q31.2
Entrez ID: 51308 HGNC ID: HGNC:17975 Ensembl Gene: ENSG00000132563 OMIM ID: 609347
Drug and gene relationship at DGIdb

 

Expression of REEP2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 REEP2 51308 205331_s_at -0.1175 0.6767
GSE20347 REEP2 51308 205331_s_at -0.1021 0.3193
GSE23400 REEP2 51308 205331_s_at -0.1440 0.0007
GSE26886 REEP2 51308 205331_s_at 0.0608 0.7489
GSE29001 REEP2 51308 205331_s_at -0.2970 0.2049
GSE38129 REEP2 51308 205331_s_at -0.2112 0.0446
GSE45670 REEP2 51308 205331_s_at 0.0344 0.7598
GSE53622 REEP2 51308 5505 -1.0364 0.0000
GSE53624 REEP2 51308 5505 -0.5051 0.0009
GSE63941 REEP2 51308 205331_s_at -0.0380 0.8847
GSE77861 REEP2 51308 205331_s_at -0.1371 0.1431
GSE97050 REEP2 51308 A_23_P19182 -0.7072 0.2612
SRP007169 REEP2 51308 RNAseq 1.5729 0.1298
SRP064894 REEP2 51308 RNAseq -0.4374 0.2719
SRP133303 REEP2 51308 RNAseq -0.2494 0.6113
SRP159526 REEP2 51308 RNAseq 0.3461 0.5879
SRP219564 REEP2 51308 RNAseq -0.8431 0.4763
TCGA REEP2 51308 RNAseq -0.5117 0.0444

Upregulated datasets: 0; Downregulated datasets: 1.  


 

Survival by REEP2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of REEP2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 REEP2 51308 3 10 17
GSE20123 REEP2 51308 4 10 16
GSE43470 REEP2 51308 4 5 34
GSE46452 REEP2 51308 0 27 32
GSE47630 REEP2 51308 0 21 19
GSE54993 REEP2 51308 9 1 60
GSE54994 REEP2 51308 3 13 37
GSE60625 REEP2 51308 0 0 11
GSE74703 REEP2 51308 3 4 29
GSE74704 REEP2 51308 3 4 13
TCGA REEP2 51308 3 37 56

Total number of gains: 32; Total number of losses: 132; Total Number of normals: 324.  


 

Somatic mutations of REEP2:

 

Generating mutation plots.

 

Highly correlated genes for REEP2:

 

Showing top 20/1126 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
REEP2SLMAP0.761582303
REEP2RASSF30.75532303
REEP2NACC20.736501403
REEP2HOXA40.729514403
REEP2LRCH20.726484404
REEP2ASB50.724587404
REEP2MRVI10.7241404
REEP2AKAP60.72362707
REEP2PRKACB0.714548303
REEP2MEF2D0.711526504
REEP2IGIP0.711137303
REEP2FAM53C0.710755303
REEP2FGL20.708936303
REEP2SH3D190.704914303
REEP2GLIPR20.702675303
REEP2HEG10.700936303
REEP2ZEB10.696451303
REEP2ADAD20.694424404
REEP2CCDC780.693673303
REEP2TET10.692278303

For details and further investigation, click here