| Full name: junctophilin 2 | Alias Symbol: JP-2 | ||
| Type: protein-coding gene | Cytoband: 20q13.12 | ||
| Entrez ID: 57158 | HGNC ID: HGNC:14202 | Ensembl Gene: ENSG00000149596 | OMIM ID: 605267 |
| Drug and gene relationship at DGIdb | |||
Expression of JPH2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | JPH2 | 57158 | 229578_at | -1.2739 | 0.2735 | |
| GSE20347 | JPH2 | 57158 | 220385_at | 0.0317 | 0.7368 | |
| GSE23400 | JPH2 | 57158 | 220385_at | -0.2376 | 0.0000 | |
| GSE26886 | JPH2 | 57158 | 1553174_at | -0.0779 | 0.5854 | |
| GSE29001 | JPH2 | 57158 | 220385_at | -0.1368 | 0.2888 | |
| GSE38129 | JPH2 | 57158 | 220385_at | -0.2653 | 0.0019 | |
| GSE45670 | JPH2 | 57158 | 1553174_at | -0.0958 | 0.2308 | |
| GSE53622 | JPH2 | 57158 | 59756 | -0.5122 | 0.0002 | |
| GSE53624 | JPH2 | 57158 | 59756 | -0.5062 | 0.0000 | |
| GSE63941 | JPH2 | 57158 | 1553174_at | 0.1223 | 0.3711 | |
| GSE77861 | JPH2 | 57158 | 1553174_at | -0.0911 | 0.4230 | |
| GSE97050 | JPH2 | 57158 | A_23_P394395 | -0.5633 | 0.2413 | |
| SRP007169 | JPH2 | 57158 | RNAseq | 3.6349 | 0.0024 | |
| SRP064894 | JPH2 | 57158 | RNAseq | -0.2139 | 0.6641 | |
| SRP133303 | JPH2 | 57158 | RNAseq | -0.8480 | 0.3126 | |
| SRP159526 | JPH2 | 57158 | RNAseq | -1.3026 | 0.0847 | |
| SRP219564 | JPH2 | 57158 | RNAseq | -0.6133 | 0.5722 | |
| TCGA | JPH2 | 57158 | RNAseq | -0.7332 | 0.0043 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by JPH2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of JPH2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | JPH2 | 57158 | 13 | 1 | 16 | |
| GSE20123 | JPH2 | 57158 | 13 | 1 | 16 | |
| GSE43470 | JPH2 | 57158 | 12 | 1 | 30 | |
| GSE46452 | JPH2 | 57158 | 29 | 0 | 30 | |
| GSE47630 | JPH2 | 57158 | 24 | 0 | 16 | |
| GSE54993 | JPH2 | 57158 | 0 | 17 | 53 | |
| GSE54994 | JPH2 | 57158 | 25 | 0 | 28 | |
| GSE60625 | JPH2 | 57158 | 0 | 0 | 11 | |
| GSE74703 | JPH2 | 57158 | 10 | 1 | 25 | |
| GSE74704 | JPH2 | 57158 | 9 | 0 | 11 | |
| TCGA | JPH2 | 57158 | 45 | 3 | 48 |
Total number of gains: 180; Total number of losses: 24; Total Number of normals: 284.
Somatic mutations of JPH2:
Generating mutation plots.
Highly correlated genes for JPH2:
Showing top 20/716 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| JPH2 | MRGPRF | 0.847883 | 3 | 0 | 3 |
| JPH2 | INMT | 0.833909 | 4 | 0 | 4 |
| JPH2 | CFL2 | 0.819543 | 3 | 0 | 3 |
| JPH2 | MTURN | 0.811183 | 3 | 0 | 3 |
| JPH2 | NUDT16 | 0.806848 | 3 | 0 | 3 |
| JPH2 | FILIP1 | 0.80509 | 3 | 0 | 3 |
| JPH2 | KAT7 | 0.793647 | 3 | 0 | 3 |
| JPH2 | PDK3 | 0.791561 | 3 | 0 | 3 |
| JPH2 | DUSP3 | 0.776827 | 5 | 0 | 5 |
| JPH2 | LSM11 | 0.769004 | 4 | 0 | 4 |
| JPH2 | EML1 | 0.750035 | 4 | 0 | 4 |
| JPH2 | CC2D2A | 0.749304 | 3 | 0 | 3 |
| JPH2 | RNF150 | 0.748093 | 3 | 0 | 3 |
| JPH2 | USP19 | 0.743186 | 3 | 0 | 3 |
| JPH2 | LONRF2 | 0.737372 | 3 | 0 | 3 |
| JPH2 | NEGR1 | 0.733691 | 3 | 0 | 3 |
| JPH2 | DHDH | 0.732933 | 3 | 0 | 3 |
| JPH2 | CACNA1H | 0.728425 | 6 | 0 | 5 |
| JPH2 | SCN7A | 0.72799 | 6 | 0 | 6 |
| JPH2 | SLMAP | 0.722557 | 4 | 0 | 3 |
For details and further investigation, click here
