| Full name: neurobeachin | Alias Symbol: KIAA1544|BCL8B|FLJ10197|LYST2 | ||
| Type: protein-coding gene | Cytoband: 13q13.3 | ||
| Entrez ID: 26960 | HGNC ID: HGNC:7648 | Ensembl Gene: ENSG00000172915 | OMIM ID: 604889 |
| Drug and gene relationship at DGIdb | |||
Expression of NBEA:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NBEA | 26960 | 221207_s_at | -2.1015 | 0.0626 | |
| GSE20347 | NBEA | 26960 | 221207_s_at | -0.2450 | 0.3891 | |
| GSE23400 | NBEA | 26960 | 221207_s_at | -0.5565 | 0.0001 | |
| GSE26886 | NBEA | 26960 | 221207_s_at | 1.1095 | 0.0344 | |
| GSE29001 | NBEA | 26960 | 221207_s_at | -0.4976 | 0.2668 | |
| GSE38129 | NBEA | 26960 | 221207_s_at | -1.0374 | 0.0166 | |
| GSE45670 | NBEA | 26960 | 221207_s_at | -2.8271 | 0.0000 | |
| GSE53622 | NBEA | 26960 | 50866 | -0.7368 | 0.0000 | |
| GSE53624 | NBEA | 26960 | 50866 | -1.6004 | 0.0000 | |
| GSE63941 | NBEA | 26960 | 221207_s_at | -2.1496 | 0.0396 | |
| GSE77861 | NBEA | 26960 | 221207_s_at | 0.2916 | 0.1058 | |
| GSE97050 | NBEA | 26960 | A_23_P65278 | -0.9348 | 0.2913 | |
| SRP007169 | NBEA | 26960 | RNAseq | 1.4790 | 0.0766 | |
| SRP008496 | NBEA | 26960 | RNAseq | 1.7031 | 0.0070 | |
| SRP064894 | NBEA | 26960 | RNAseq | -1.5655 | 0.0000 | |
| SRP133303 | NBEA | 26960 | RNAseq | -0.8318 | 0.0478 | |
| SRP159526 | NBEA | 26960 | RNAseq | -0.9481 | 0.0026 | |
| SRP193095 | NBEA | 26960 | RNAseq | 0.6410 | 0.0610 | |
| SRP219564 | NBEA | 26960 | RNAseq | -1.0972 | 0.2663 | |
| TCGA | NBEA | 26960 | RNAseq | -1.0046 | 0.0007 |
Upregulated datasets: 2; Downregulated datasets: 6.
Survival by NBEA expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NBEA:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NBEA | 26960 | 0 | 16 | 14 | |
| GSE20123 | NBEA | 26960 | 0 | 15 | 15 | |
| GSE43470 | NBEA | 26960 | 2 | 13 | 28 | |
| GSE46452 | NBEA | 26960 | 0 | 33 | 26 | |
| GSE47630 | NBEA | 26960 | 2 | 27 | 11 | |
| GSE54993 | NBEA | 26960 | 12 | 2 | 56 | |
| GSE54994 | NBEA | 26960 | 1 | 17 | 35 | |
| GSE60625 | NBEA | 26960 | 0 | 3 | 8 | |
| GSE74703 | NBEA | 26960 | 2 | 10 | 24 | |
| GSE74704 | NBEA | 26960 | 0 | 12 | 8 | |
| TCGA | NBEA | 26960 | 8 | 40 | 48 |
Total number of gains: 27; Total number of losses: 188; Total Number of normals: 273.
Somatic mutations of NBEA:
Generating mutation plots.
Highly correlated genes for NBEA:
Showing top 20/663 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NBEA | ANKDD1A | 0.786841 | 3 | 0 | 3 |
| NBEA | RBPMS2 | 0.774996 | 5 | 0 | 5 |
| NBEA | PRKAR2B | 0.774878 | 10 | 0 | 10 |
| NBEA | ANO5 | 0.768915 | 4 | 0 | 4 |
| NBEA | RAB9B | 0.757957 | 5 | 0 | 4 |
| NBEA | TCEAL2 | 0.755125 | 10 | 0 | 9 |
| NBEA | C8orf88 | 0.751668 | 3 | 0 | 3 |
| NBEA | BHMT2 | 0.746082 | 8 | 0 | 7 |
| NBEA | MSRB3 | 0.742284 | 5 | 0 | 4 |
| NBEA | KCNT2 | 0.739993 | 6 | 0 | 5 |
| NBEA | RAI2 | 0.739801 | 11 | 0 | 9 |
| NBEA | PDZRN4 | 0.735683 | 8 | 0 | 7 |
| NBEA | CBX7 | 0.735672 | 8 | 0 | 8 |
| NBEA | CAMK2G | 0.734534 | 4 | 0 | 4 |
| NBEA | A2M-AS1 | 0.73094 | 4 | 0 | 3 |
| NBEA | ITGA7 | 0.727973 | 8 | 0 | 7 |
| NBEA | PLN | 0.726321 | 9 | 0 | 8 |
| NBEA | MRVI1 | 0.725914 | 5 | 0 | 4 |
| NBEA | PLCB4 | 0.725426 | 9 | 0 | 8 |
| NBEA | RNF150 | 0.724932 | 7 | 0 | 6 |
For details and further investigation, click here
