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Multi-Omics Database of ESCC

 

C8orf88

 

Full name: chromosome 8 open reading frame 88 Alias Symbol: 
Type: protein-coding gene Cytoband: 8q21.3
Entrez ID: 100127983 HGNC ID: HGNC:44672 Ensembl Gene: ENSG00000253250 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of C8orf88:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 C8orf88 100127983 228107_at -0.8403 0.5062
GSE26886 C8orf88 100127983 228107_at 0.1149 0.5061
GSE45670 C8orf88 100127983 228107_at -1.6235 0.0001
GSE63941 C8orf88 100127983 228107_at -1.4900 0.3086
GSE77861 C8orf88 100127983 228107_at -0.0686 0.7378
SRP064894 C8orf88 100127983 RNAseq 0.0964 0.7988
SRP133303 C8orf88 100127983 RNAseq -0.4804 0.4248
SRP159526 C8orf88 100127983 RNAseq -0.5311 0.2717
SRP219564 C8orf88 100127983 RNAseq -0.5684 0.5706

Upregulated datasets: 0; Downregulated datasets: 1.  

 

Copy number change of C8orf88:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 C8orf88 100127983 14 1 15
GSE20123 C8orf88 100127983 15 1 14
GSE43470 C8orf88 100127983 20 1 22
GSE46452 C8orf88 100127983 22 0 37
GSE47630 C8orf88 100127983 24 0 16
GSE54993 C8orf88 100127983 0 20 50
GSE54994 C8orf88 100127983 33 1 19
GSE60625 C8orf88 100127983 0 4 7
GSE74703 C8orf88 100127983 17 1 18
GSE74704 C8orf88 100127983 10 0 10

Total number of gains: 155; Total number of losses: 29; Total Number of normals: 208.  

 

Somatic mutations of C8orf88:

 

Generating mutation plots.

 

Highly correlated genes for C8orf88:

 

Showing top 20/111 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
C8orf88NBEA0.751668303
C8orf88TGFB1I10.73368303
C8orf88ITGBL10.7262303
C8orf88CAP20.715095303
C8orf88PDE1A0.705063403
C8orf88LIX1L0.698547303
C8orf88TOR1AIP10.697916303
C8orf88VIM0.695082303
C8orf88NCAM10.694138303
C8orf88PLCL10.693423303
C8orf88SERINC10.687114303
C8orf88TMOD10.684954303
C8orf88PTPRM0.684461303
C8orf88EFHD10.683411303
C8orf88CLMP0.678965303
C8orf88SMAD90.675719403
C8orf88TOX0.672819303
C8orf88GPRASP10.672743303
C8orf88RNASE40.671125404
C8orf88LAMA20.670894303

For details and further investigation, click here