| Full name: chromobox 7 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 22q13.1 | ||
| Entrez ID: 23492 | HGNC ID: HGNC:1557 | Ensembl Gene: ENSG00000100307 | OMIM ID: 608457 |
| Drug and gene relationship at DGIdb | |||
Expression of CBX7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CBX7 | 23492 | 212914_at | -0.9235 | 0.3249 | |
| GSE20347 | CBX7 | 23492 | 212914_at | -0.1690 | 0.3001 | |
| GSE23400 | CBX7 | 23492 | 212914_at | -0.6864 | 0.0000 | |
| GSE26886 | CBX7 | 23492 | 212914_at | -0.2602 | 0.5145 | |
| GSE29001 | CBX7 | 23492 | 212914_at | -0.3756 | 0.2871 | |
| GSE38129 | CBX7 | 23492 | 212914_at | -0.8367 | 0.0035 | |
| GSE45670 | CBX7 | 23492 | 212914_at | -1.2588 | 0.0000 | |
| GSE53622 | CBX7 | 23492 | 2813 | -1.6360 | 0.0000 | |
| GSE53624 | CBX7 | 23492 | 2813 | -1.3177 | 0.0000 | |
| GSE63941 | CBX7 | 23492 | 212914_at | -0.2068 | 0.7195 | |
| GSE77861 | CBX7 | 23492 | 212914_at | 0.0238 | 0.8949 | |
| GSE97050 | CBX7 | 23492 | A_33_P3343845 | -0.7601 | 0.2226 | |
| SRP007169 | CBX7 | 23492 | RNAseq | -0.3245 | 0.5470 | |
| SRP008496 | CBX7 | 23492 | RNAseq | 0.0697 | 0.8501 | |
| SRP064894 | CBX7 | 23492 | RNAseq | -0.6747 | 0.0059 | |
| SRP133303 | CBX7 | 23492 | RNAseq | -1.2039 | 0.0002 | |
| SRP159526 | CBX7 | 23492 | RNAseq | -0.7252 | 0.0232 | |
| SRP193095 | CBX7 | 23492 | RNAseq | -0.0347 | 0.8783 | |
| SRP219564 | CBX7 | 23492 | RNAseq | -0.7845 | 0.2793 | |
| TCGA | CBX7 | 23492 | RNAseq | -0.6666 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by CBX7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CBX7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CBX7 | 23492 | 6 | 5 | 19 | |
| GSE20123 | CBX7 | 23492 | 6 | 4 | 20 | |
| GSE43470 | CBX7 | 23492 | 5 | 5 | 33 | |
| GSE46452 | CBX7 | 23492 | 32 | 2 | 25 | |
| GSE47630 | CBX7 | 23492 | 9 | 4 | 27 | |
| GSE54993 | CBX7 | 23492 | 3 | 6 | 61 | |
| GSE54994 | CBX7 | 23492 | 10 | 7 | 36 | |
| GSE60625 | CBX7 | 23492 | 5 | 0 | 6 | |
| GSE74703 | CBX7 | 23492 | 5 | 4 | 27 | |
| GSE74704 | CBX7 | 23492 | 3 | 2 | 15 | |
| TCGA | CBX7 | 23492 | 27 | 15 | 54 |
Total number of gains: 111; Total number of losses: 54; Total Number of normals: 323.
Somatic mutations of CBX7:
Generating mutation plots.
Highly correlated genes for CBX7:
Showing top 20/1382 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CBX7 | CYP21A2 | 0.864241 | 3 | 0 | 3 |
| CBX7 | PARD3B | 0.863943 | 4 | 0 | 4 |
| CBX7 | C1QTNF7 | 0.859114 | 5 | 0 | 5 |
| CBX7 | FIBIN | 0.858818 | 3 | 0 | 3 |
| CBX7 | CLEC3B | 0.836343 | 3 | 0 | 3 |
| CBX7 | TNS1 | 0.826974 | 9 | 0 | 9 |
| CBX7 | FENDRR | 0.824393 | 4 | 0 | 4 |
| CBX7 | XKR4 | 0.816002 | 6 | 0 | 6 |
| CBX7 | RGS7BP | 0.813668 | 5 | 0 | 5 |
| CBX7 | LRRN4CL | 0.81023 | 5 | 0 | 5 |
| CBX7 | ITGA7 | 0.8085 | 9 | 0 | 9 |
| CBX7 | FXYD1 | 0.807498 | 7 | 0 | 7 |
| CBX7 | PRKAR2B | 0.805823 | 9 | 0 | 8 |
| CBX7 | TCEAL1 | 0.802491 | 7 | 0 | 7 |
| CBX7 | LINC01082 | 0.800873 | 4 | 0 | 4 |
| CBX7 | RBPMS2 | 0.793903 | 6 | 0 | 5 |
| CBX7 | FRMD3 | 0.792763 | 5 | 0 | 5 |
| CBX7 | SMTN | 0.789025 | 6 | 0 | 6 |
| CBX7 | PPP1R14A | 0.783773 | 5 | 0 | 5 |
| CBX7 | MRVI1 | 0.783344 | 6 | 0 | 5 |
For details and further investigation, click here
