| Full name: nuclear factor, erythroid 2 | Alias Symbol: NF-E2 | ||
| Type: protein-coding gene | Cytoband: 12q13 | ||
| Entrez ID: 4778 | HGNC ID: HGNC:7780 | Ensembl Gene: ENSG00000123405 | OMIM ID: 601490 |
| Drug and gene relationship at DGIdb | |||
Expression of NFE2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NFE2 | 4778 | 209930_s_at | 0.0950 | 0.7841 | |
| GSE20347 | NFE2 | 4778 | 209930_s_at | -0.0129 | 0.8618 | |
| GSE23400 | NFE2 | 4778 | 209930_s_at | -0.0303 | 0.3939 | |
| GSE26886 | NFE2 | 4778 | 209930_s_at | 0.0307 | 0.7965 | |
| GSE29001 | NFE2 | 4778 | 209930_s_at | -0.1263 | 0.1553 | |
| GSE38129 | NFE2 | 4778 | 209930_s_at | 0.0249 | 0.7148 | |
| GSE45670 | NFE2 | 4778 | 209930_s_at | 0.2344 | 0.0536 | |
| GSE53622 | NFE2 | 4778 | 41657 | 0.1153 | 0.6583 | |
| GSE53624 | NFE2 | 4778 | 41657 | 0.8003 | 0.0007 | |
| GSE63941 | NFE2 | 4778 | 209930_s_at | 0.0948 | 0.7381 | |
| GSE77861 | NFE2 | 4778 | 209930_s_at | 0.0044 | 0.9750 | |
| GSE97050 | NFE2 | 4778 | A_23_P13753 | -0.1216 | 0.6423 | |
| TCGA | NFE2 | 4778 | RNAseq | 0.3696 | 0.3768 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NFE2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NFE2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NFE2 | 4778 | 4 | 1 | 25 | |
| GSE20123 | NFE2 | 4778 | 4 | 1 | 25 | |
| GSE43470 | NFE2 | 4778 | 3 | 0 | 40 | |
| GSE46452 | NFE2 | 4778 | 7 | 1 | 51 | |
| GSE47630 | NFE2 | 4778 | 10 | 2 | 28 | |
| GSE54993 | NFE2 | 4778 | 0 | 5 | 65 | |
| GSE54994 | NFE2 | 4778 | 4 | 1 | 48 | |
| GSE60625 | NFE2 | 4778 | 0 | 0 | 11 | |
| GSE74703 | NFE2 | 4778 | 3 | 0 | 33 | |
| GSE74704 | NFE2 | 4778 | 3 | 1 | 16 | |
| TCGA | NFE2 | 4778 | 15 | 11 | 70 |
Total number of gains: 53; Total number of losses: 23; Total Number of normals: 412.
Somatic mutations of NFE2:
Generating mutation plots.
Highly correlated genes for NFE2:
Showing top 20/119 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NFE2 | GPR135 | 0.710547 | 3 | 0 | 3 |
| NFE2 | CXCR6 | 0.695795 | 3 | 0 | 3 |
| NFE2 | FSTL4 | 0.692711 | 4 | 0 | 4 |
| NFE2 | PROK2 | 0.681026 | 5 | 0 | 5 |
| NFE2 | C19orf38 | 0.678291 | 3 | 0 | 3 |
| NFE2 | PTH1R | 0.665974 | 3 | 0 | 3 |
| NFE2 | CPSF1 | 0.663934 | 3 | 0 | 3 |
| NFE2 | CATSPER1 | 0.654322 | 4 | 0 | 3 |
| NFE2 | ARRB1 | 0.643768 | 3 | 0 | 3 |
| NFE2 | LILRB5 | 0.630626 | 4 | 0 | 4 |
| NFE2 | DAB2IP | 0.630265 | 3 | 0 | 3 |
| NFE2 | NPTXR | 0.621693 | 4 | 0 | 3 |
| NFE2 | PIGS | 0.619974 | 3 | 0 | 3 |
| NFE2 | CAPN8 | 0.617925 | 3 | 0 | 3 |
| NFE2 | RILP | 0.615046 | 3 | 0 | 3 |
| NFE2 | PDE1B | 0.614886 | 4 | 0 | 3 |
| NFE2 | H6PD | 0.613954 | 3 | 0 | 3 |
| NFE2 | FGF16 | 0.612584 | 4 | 0 | 3 |
| NFE2 | RBP2 | 0.611171 | 4 | 0 | 3 |
| NFE2 | OR2J2 | 0.608811 | 4 | 0 | 3 |
For details and further investigation, click here
