| Full name: neuronal pentraxin receptor | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 22q13.1 | ||
| Entrez ID: 23467 | HGNC ID: HGNC:7954 | Ensembl Gene: ENSG00000221890 | OMIM ID: 609474 |
| Drug and gene relationship at DGIdb | |||
Expression of NPTXR:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NPTXR | 23467 | 217041_at | -0.0944 | 0.7730 | |
| GSE20347 | NPTXR | 23467 | 217041_at | -0.0334 | 0.7204 | |
| GSE23400 | NPTXR | 23467 | 217041_at | -0.1875 | 0.0000 | |
| GSE26886 | NPTXR | 23467 | 217041_at | 0.1412 | 0.2008 | |
| GSE29001 | NPTXR | 23467 | 217041_at | -0.0009 | 0.9954 | |
| GSE38129 | NPTXR | 23467 | 217041_at | -0.1870 | 0.0369 | |
| GSE45670 | NPTXR | 23467 | 217041_at | 0.0296 | 0.7124 | |
| GSE53622 | NPTXR | 23467 | 17117 | 0.0743 | 0.6819 | |
| GSE53624 | NPTXR | 23467 | 17117 | 0.0026 | 0.9802 | |
| GSE63941 | NPTXR | 23467 | 213040_s_at | 0.6154 | 0.5061 | |
| GSE77861 | NPTXR | 23467 | 217041_at | -0.0965 | 0.5237 | |
| GSE97050 | NPTXR | 23467 | A_23_P29282 | -0.3324 | 0.5200 | |
| SRP064894 | NPTXR | 23467 | RNAseq | -0.2709 | 0.5056 | |
| SRP133303 | NPTXR | 23467 | RNAseq | 0.2063 | 0.4375 | |
| SRP159526 | NPTXR | 23467 | RNAseq | 1.6242 | 0.0000 | |
| SRP193095 | NPTXR | 23467 | RNAseq | 1.5985 | 0.0000 | |
| SRP219564 | NPTXR | 23467 | RNAseq | 0.4140 | 0.5885 | |
| TCGA | NPTXR | 23467 | RNAseq | -0.2340 | 0.2664 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by NPTXR expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NPTXR:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NPTXR | 23467 | 6 | 5 | 19 | |
| GSE20123 | NPTXR | 23467 | 6 | 4 | 20 | |
| GSE43470 | NPTXR | 23467 | 5 | 5 | 33 | |
| GSE46452 | NPTXR | 23467 | 32 | 2 | 25 | |
| GSE47630 | NPTXR | 23467 | 9 | 4 | 27 | |
| GSE54993 | NPTXR | 23467 | 3 | 6 | 61 | |
| GSE54994 | NPTXR | 23467 | 9 | 7 | 37 | |
| GSE60625 | NPTXR | 23467 | 5 | 0 | 6 | |
| GSE74703 | NPTXR | 23467 | 5 | 4 | 27 | |
| GSE74704 | NPTXR | 23467 | 3 | 2 | 15 | |
| TCGA | NPTXR | 23467 | 27 | 15 | 54 |
Total number of gains: 110; Total number of losses: 54; Total Number of normals: 324.
Somatic mutations of NPTXR:
Generating mutation plots.
Highly correlated genes for NPTXR:
Showing top 20/1054 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NPTXR | C2CD4B | 0.801041 | 3 | 0 | 3 |
| NPTXR | DNAJC4 | 0.756936 | 3 | 0 | 3 |
| NPTXR | GABRA1 | 0.732444 | 4 | 0 | 4 |
| NPTXR | TREML2 | 0.727165 | 7 | 0 | 7 |
| NPTXR | SSPO | 0.716626 | 4 | 0 | 4 |
| NPTXR | OR10J1 | 0.715097 | 5 | 0 | 5 |
| NPTXR | APC2 | 0.712121 | 6 | 0 | 6 |
| NPTXR | PF4 | 0.709995 | 5 | 0 | 5 |
| NPTXR | VGF | 0.705696 | 4 | 0 | 4 |
| NPTXR | CHRD | 0.705393 | 5 | 0 | 5 |
| NPTXR | EPX | 0.704809 | 4 | 0 | 4 |
| NPTXR | IRS4 | 0.704065 | 5 | 0 | 5 |
| NPTXR | GSTM2 | 0.703521 | 3 | 0 | 3 |
| NPTXR | AFP | 0.697208 | 4 | 0 | 4 |
| NPTXR | IGH | 0.696462 | 7 | 0 | 6 |
| NPTXR | CAMK2B | 0.693855 | 7 | 0 | 6 |
| NPTXR | MUC13 | 0.693325 | 5 | 0 | 5 |
| NPTXR | C11orf16 | 0.690063 | 8 | 0 | 7 |
| NPTXR | GJA8 | 0.689744 | 6 | 0 | 5 |
| NPTXR | RASGRP2 | 0.689172 | 4 | 0 | 4 |
For details and further investigation, click here
