NFIL3

 

Full name: nuclear factor, interleukin 3 regulated Alias Symbol: E4BP4|NFIL3A|NF-IL3A
Type: protein-coding gene Cytoband: 9q22.31
Entrez ID: 4783 HGNC ID: HGNC:7787 Ensembl Gene: ENSG00000165030 OMIM ID: 605327
Drug and gene relationship at DGIdb

 

Expression of NFIL3:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 NFIL3 4783 203574_at -0.3209 0.6876
GSE20347 NFIL3 4783 203574_at 0.6382 0.0352
GSE23400 NFIL3 4783 203574_at 0.8360 0.0000
GSE26886 NFIL3 4783 203574_at 2.0900 0.0000
GSE29001 NFIL3 4783 203574_at 0.9238 0.0168
GSE38129 NFIL3 4783 203574_at 0.4521 0.1128
GSE45670 NFIL3 4783 203574_at 0.1662 0.6721
GSE53622 NFIL3 4783 93183 0.3309 0.0109
GSE53624 NFIL3 4783 93183 0.6202 0.0000
GSE63941 NFIL3 4783 203574_at -0.3328 0.6265
GSE77861 NFIL3 4783 203574_at 1.5611 0.0009
GSE97050 NFIL3 4783 A_23_P32253 -0.2506 0.6035
SRP007169 NFIL3 4783 RNAseq 0.3725 0.4291
SRP008496 NFIL3 4783 RNAseq 1.0197 0.0060
SRP064894 NFIL3 4783 RNAseq 0.3680 0.2533
SRP133303 NFIL3 4783 RNAseq 0.8435 0.0043
SRP159526 NFIL3 4783 RNAseq 0.3870 0.3350
SRP193095 NFIL3 4783 RNAseq 1.1680 0.0000
SRP219564 NFIL3 4783 RNAseq 0.3811 0.5624
TCGA NFIL3 4783 RNAseq 0.0247 0.7516

Upregulated datasets: 4; Downregulated datasets: 0.  

 

Survival by NFIL3 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of NFIL3:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 NFIL3 4783 6 9 15
GSE20123 NFIL3 4783 6 9 15
GSE43470 NFIL3 4783 6 3 34
GSE46452 NFIL3 4783 6 14 39
GSE47630 NFIL3 4783 1 18 21
GSE54993 NFIL3 4783 4 2 64
GSE54994 NFIL3 4783 7 11 35
GSE60625 NFIL3 4783 0 0 11
GSE74703 NFIL3 4783 5 3 28
GSE74704 NFIL3 4783 3 7 10
TCGA NFIL3 4783 22 24 50

Total number of gains: 66; Total number of losses: 100; Total Number of normals: 322.  

 

Somatic mutations of NFIL3:

 

Generating mutation plots.

 

Highly correlated genes for NFIL3:

 

Showing top 20/1000 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
NFIL3ZFHX30.817932303
NFIL3CNRIP10.774828303
NFIL3WDR810.774504303
NFIL3KIAA1324L0.773238303
NFIL3MATN40.767296303
NFIL3AKR1E20.754391303
NFIL3PPP1R350.749885303
NFIL3EIF3L0.748677303
NFIL3DNAJC180.742938303
NFIL3STXBP40.738423303
NFIL3HEATR60.736852303
NFIL3ICAM50.736485303
NFIL3JMY0.732159403
NFIL3SAFB20.731697403
NFIL3PLEKHA30.727679403
NFIL3SSBP40.726752303
NFIL3ANXA60.721057404
NFIL3ZCRB10.719814403
NFIL3ZNF3190.719803303
NFIL3TIMP40.715537303

For details and further investigation, click here