| Full name: intercellular adhesion molecule 5 | Alias Symbol: TLN | ||
| Type: protein-coding gene | Cytoband: 19p13.2 | ||
| Entrez ID: 7087 | HGNC ID: HGNC:5348 | Ensembl Gene: ENSG00000105376 | OMIM ID: 601852 |
| Drug and gene relationship at DGIdb | |||
Expression of ICAM5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ICAM5 | 7087 | 206906_at | 0.1429 | 0.6378 | |
| GSE20347 | ICAM5 | 7087 | 206906_at | 0.1917 | 0.0142 | |
| GSE23400 | ICAM5 | 7087 | 206906_at | 0.1434 | 0.0009 | |
| GSE26886 | ICAM5 | 7087 | 206906_at | 0.6994 | 0.0000 | |
| GSE29001 | ICAM5 | 7087 | 206906_at | 0.2363 | 0.1890 | |
| GSE38129 | ICAM5 | 7087 | 206906_at | 0.2237 | 0.0061 | |
| GSE45670 | ICAM5 | 7087 | 206906_at | 0.2425 | 0.0357 | |
| GSE53622 | ICAM5 | 7087 | 116790 | 0.4647 | 0.0000 | |
| GSE53624 | ICAM5 | 7087 | 116790 | 0.9568 | 0.0000 | |
| GSE63941 | ICAM5 | 7087 | 206906_at | 0.4039 | 0.2107 | |
| GSE77861 | ICAM5 | 7087 | 206906_at | 0.0070 | 0.9630 | |
| GSE97050 | ICAM5 | 7087 | A_23_P119143 | 0.1144 | 0.5544 | |
| SRP133303 | ICAM5 | 7087 | RNAseq | 1.0578 | 0.0182 | |
| SRP219564 | ICAM5 | 7087 | RNAseq | 2.1679 | 0.0042 | |
| TCGA | ICAM5 | 7087 | RNAseq | 2.0927 | 0.0000 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by ICAM5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ICAM5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ICAM5 | 7087 | 4 | 3 | 23 | |
| GSE20123 | ICAM5 | 7087 | 3 | 1 | 26 | |
| GSE43470 | ICAM5 | 7087 | 3 | 6 | 34 | |
| GSE46452 | ICAM5 | 7087 | 47 | 1 | 11 | |
| GSE47630 | ICAM5 | 7087 | 4 | 7 | 29 | |
| GSE54993 | ICAM5 | 7087 | 16 | 3 | 51 | |
| GSE54994 | ICAM5 | 7087 | 7 | 13 | 33 | |
| GSE60625 | ICAM5 | 7087 | 9 | 0 | 2 | |
| GSE74703 | ICAM5 | 7087 | 3 | 4 | 29 | |
| GSE74704 | ICAM5 | 7087 | 0 | 1 | 19 | |
| TCGA | ICAM5 | 7087 | 13 | 15 | 68 |
Total number of gains: 109; Total number of losses: 54; Total Number of normals: 325.
Somatic mutations of ICAM5:
Generating mutation plots.
Highly correlated genes for ICAM5:
Showing top 20/660 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ICAM5 | CORO1C | 0.815868 | 3 | 0 | 3 |
| ICAM5 | FAM131B | 0.810821 | 3 | 0 | 3 |
| ICAM5 | TGFB3 | 0.805215 | 3 | 0 | 3 |
| ICAM5 | FARS2 | 0.767232 | 3 | 0 | 3 |
| ICAM5 | SLC39A3 | 0.759837 | 3 | 0 | 3 |
| ICAM5 | PLEKHO2 | 0.743078 | 3 | 0 | 3 |
| ICAM5 | ZNF8 | 0.742129 | 3 | 0 | 3 |
| ICAM5 | NFIL3 | 0.736485 | 3 | 0 | 3 |
| ICAM5 | HIC1 | 0.731102 | 3 | 0 | 3 |
| ICAM5 | NACC1 | 0.729634 | 3 | 0 | 3 |
| ICAM5 | ENG | 0.727479 | 4 | 0 | 4 |
| ICAM5 | CD180 | 0.726448 | 3 | 0 | 3 |
| ICAM5 | LRRC55 | 0.725189 | 3 | 0 | 3 |
| ICAM5 | TPCN2 | 0.721318 | 3 | 0 | 3 |
| ICAM5 | CYTH3 | 0.720405 | 3 | 0 | 3 |
| ICAM5 | GTDC1 | 0.718958 | 3 | 0 | 3 |
| ICAM5 | KCNAB2 | 0.714621 | 4 | 0 | 4 |
| ICAM5 | RAB3A | 0.713969 | 3 | 0 | 3 |
| ICAM5 | SCMH1 | 0.713279 | 3 | 0 | 3 |
| ICAM5 | RAD18 | 0.708992 | 3 | 0 | 3 |
For details and further investigation, click here
