| Full name: zinc finger protein 135 | Alias Symbol: pHZ-17 | ||
| Type: protein-coding gene | Cytoband: 19q13.4 | ||
| Entrez ID: 7694 | HGNC ID: HGNC:12919 | Ensembl Gene: ENSG00000176293 | OMIM ID: 604077 |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF135:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF135 | 7694 | 1567410_at | 0.0994 | 0.7438 | |
| GSE20347 | ZNF135 | 7694 | 206142_at | -0.1676 | 0.0237 | |
| GSE23400 | ZNF135 | 7694 | 206142_at | -0.0440 | 0.0890 | |
| GSE26886 | ZNF135 | 7694 | 1567410_at | -0.2170 | 0.2829 | |
| GSE29001 | ZNF135 | 7694 | 206142_at | -0.6280 | 0.0004 | |
| GSE38129 | ZNF135 | 7694 | 206142_at | -0.3354 | 0.0001 | |
| GSE45670 | ZNF135 | 7694 | 1567410_at | 0.2091 | 0.0390 | |
| GSE53622 | ZNF135 | 7694 | 104046 | -1.0501 | 0.0000 | |
| GSE53624 | ZNF135 | 7694 | 104046 | -1.2723 | 0.0000 | |
| GSE63941 | ZNF135 | 7694 | 1567410_at | 0.2668 | 0.1667 | |
| GSE77861 | ZNF135 | 7694 | 1567410_at | -0.1505 | 0.1903 | |
| GSE97050 | ZNF135 | 7694 | A_23_P348227 | -0.3966 | 0.1581 | |
| SRP064894 | ZNF135 | 7694 | RNAseq | -0.8774 | 0.0177 | |
| SRP133303 | ZNF135 | 7694 | RNAseq | -1.5201 | 0.0001 | |
| SRP193095 | ZNF135 | 7694 | RNAseq | -0.7694 | 0.0076 | |
| SRP219564 | ZNF135 | 7694 | RNAseq | -1.0183 | 0.2451 | |
| TCGA | ZNF135 | 7694 | RNAseq | -0.9509 | 0.0018 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by ZNF135 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF135:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF135 | 7694 | 2 | 4 | 24 | |
| GSE20123 | ZNF135 | 7694 | 2 | 3 | 25 | |
| GSE43470 | ZNF135 | 7694 | 3 | 9 | 31 | |
| GSE46452 | ZNF135 | 7694 | 45 | 1 | 13 | |
| GSE47630 | ZNF135 | 7694 | 8 | 6 | 26 | |
| GSE54993 | ZNF135 | 7694 | 18 | 4 | 48 | |
| GSE54994 | ZNF135 | 7694 | 5 | 12 | 36 | |
| GSE60625 | ZNF135 | 7694 | 9 | 0 | 2 | |
| GSE74703 | ZNF135 | 7694 | 3 | 6 | 27 | |
| GSE74704 | ZNF135 | 7694 | 2 | 1 | 17 | |
| TCGA | ZNF135 | 7694 | 20 | 15 | 61 |
Total number of gains: 117; Total number of losses: 61; Total Number of normals: 310.
Somatic mutations of ZNF135:
Generating mutation plots.
Highly correlated genes for ZNF135:
Showing top 20/187 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF135 | ZNF285 | 0.699974 | 3 | 0 | 3 |
| ZNF135 | CLVS1 | 0.693755 | 3 | 0 | 3 |
| ZNF135 | EIF4E3 | 0.686564 | 3 | 0 | 3 |
| ZNF135 | HABP2 | 0.685238 | 3 | 0 | 3 |
| ZNF135 | GOLGA6L6 | 0.672635 | 3 | 0 | 3 |
| ZNF135 | LRP2 | 0.663356 | 4 | 0 | 3 |
| ZNF135 | KIF25 | 0.655811 | 3 | 0 | 3 |
| ZNF135 | RS1 | 0.653861 | 4 | 0 | 3 |
| ZNF135 | LINC00290 | 0.646405 | 4 | 0 | 3 |
| ZNF135 | BTBD8 | 0.644407 | 3 | 0 | 3 |
| ZNF135 | GPR26 | 0.641948 | 4 | 0 | 3 |
| ZNF135 | SLC12A1 | 0.639193 | 3 | 0 | 3 |
| ZNF135 | TSGA10 | 0.638597 | 3 | 0 | 3 |
| ZNF135 | BEST4 | 0.638589 | 3 | 0 | 3 |
| ZNF135 | TNXB | 0.637594 | 5 | 0 | 5 |
| ZNF135 | MYZAP | 0.637139 | 3 | 0 | 3 |
| ZNF135 | C10orf67 | 0.631022 | 3 | 0 | 3 |
| ZNF135 | OR4D2 | 0.623662 | 3 | 0 | 3 |
| ZNF135 | LINC00937 | 0.622368 | 4 | 0 | 4 |
| ZNF135 | ADCY1 | 0.616508 | 3 | 0 | 3 |
For details and further investigation, click here
