| Full name: aquaporin 9 | Alias Symbol: SSC1|HsT17287 | ||
| Type: protein-coding gene | Cytoband: 15q21.3 | ||
| Entrez ID: 366 | HGNC ID: HGNC:643 | Ensembl Gene: ENSG00000103569 | OMIM ID: 602914 |
| Drug and gene relationship at DGIdb | |||
Expression of AQP9:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AQP9 | 366 | 205568_at | 1.1861 | 0.3965 | |
| GSE20347 | AQP9 | 366 | 205568_at | 0.2499 | 0.0422 | |
| GSE23400 | AQP9 | 366 | 205568_at | 0.0395 | 0.5794 | |
| GSE26886 | AQP9 | 366 | 205568_at | -0.3082 | 0.0515 | |
| GSE29001 | AQP9 | 366 | 205568_at | -0.0551 | 0.8071 | |
| GSE38129 | AQP9 | 366 | 205568_at | 0.2634 | 0.0636 | |
| GSE45670 | AQP9 | 366 | 205568_at | 0.3255 | 0.3206 | |
| GSE53622 | AQP9 | 366 | 46155 | 1.6898 | 0.0000 | |
| GSE53624 | AQP9 | 366 | 46155 | 2.2113 | 0.0000 | |
| GSE63941 | AQP9 | 366 | 205568_at | -0.0746 | 0.7006 | |
| GSE77861 | AQP9 | 366 | 205568_at | 0.0718 | 0.5868 | |
| GSE97050 | AQP9 | 366 | A_23_P106362 | 0.0787 | 0.8389 | |
| SRP008496 | AQP9 | 366 | RNAseq | 3.1184 | 0.0036 | |
| SRP064894 | AQP9 | 366 | RNAseq | 2.2954 | 0.0001 | |
| SRP133303 | AQP9 | 366 | RNAseq | 3.4338 | 0.0000 | |
| SRP193095 | AQP9 | 366 | RNAseq | 3.8328 | 0.0000 | |
| TCGA | AQP9 | 366 | RNAseq | 0.7464 | 0.0062 |
Upregulated datasets: 6; Downregulated datasets: 0.
Survival by AQP9 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AQP9:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AQP9 | 366 | 6 | 4 | 20 | |
| GSE20123 | AQP9 | 366 | 6 | 3 | 21 | |
| GSE43470 | AQP9 | 366 | 4 | 4 | 35 | |
| GSE46452 | AQP9 | 366 | 3 | 7 | 49 | |
| GSE47630 | AQP9 | 366 | 8 | 10 | 22 | |
| GSE54993 | AQP9 | 366 | 5 | 6 | 59 | |
| GSE54994 | AQP9 | 366 | 6 | 8 | 39 | |
| GSE60625 | AQP9 | 366 | 4 | 0 | 7 | |
| GSE74703 | AQP9 | 366 | 4 | 3 | 29 | |
| GSE74704 | AQP9 | 366 | 2 | 3 | 15 | |
| TCGA | AQP9 | 366 | 10 | 16 | 70 |
Total number of gains: 58; Total number of losses: 64; Total Number of normals: 366.
Somatic mutations of AQP9:
Generating mutation plots.
Highly correlated genes for AQP9:
Showing top 20/337 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AQP9 | FCGR3A | 0.798885 | 3 | 0 | 3 |
| AQP9 | CMTM2 | 0.788005 | 5 | 0 | 5 |
| AQP9 | MCEMP1 | 0.752825 | 4 | 0 | 4 |
| AQP9 | TNFRSF10C | 0.725768 | 4 | 0 | 4 |
| AQP9 | C19orf38 | 0.721701 | 3 | 0 | 3 |
| AQP9 | EMP3 | 0.711993 | 3 | 0 | 3 |
| AQP9 | PPP1R18 | 0.696884 | 4 | 0 | 4 |
| AQP9 | TRIM37 | 0.691917 | 3 | 0 | 3 |
| AQP9 | PROK2 | 0.688884 | 8 | 0 | 6 |
| AQP9 | DPP4 | 0.683207 | 5 | 0 | 5 |
| AQP9 | NMUR2 | 0.675949 | 3 | 0 | 3 |
| AQP9 | RFTN2 | 0.670386 | 3 | 0 | 3 |
| AQP9 | NCF2 | 0.66954 | 6 | 0 | 4 |
| AQP9 | MKNK1 | 0.667802 | 3 | 0 | 3 |
| AQP9 | C5AR1 | 0.65625 | 11 | 0 | 8 |
| AQP9 | FAM167B | 0.655445 | 3 | 0 | 3 |
| AQP9 | LRRC8C | 0.651658 | 3 | 0 | 3 |
| AQP9 | LCP2 | 0.647166 | 9 | 0 | 8 |
| AQP9 | MNDA | 0.644395 | 10 | 0 | 7 |
| AQP9 | CXCR1 | 0.642256 | 8 | 0 | 6 |
For details and further investigation, click here
