| Full name: feline leukemia virus subgroup C cellular receptor family member 2 | Alias Symbol: FLJ20371|MFSD7C|SLC49A2|CCT | ||
| Type: protein-coding gene | Cytoband: 14q24.3 | ||
| Entrez ID: 55640 | HGNC ID: HGNC:20105 | Ensembl Gene: ENSG00000119686 | OMIM ID: 610865 |
| Drug and gene relationship at DGIdb | |||
Expression of FLVCR2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FLVCR2 | 55640 | 219316_s_at | 0.3717 | 0.7283 | |
| GSE20347 | FLVCR2 | 55640 | 219316_s_at | -0.0116 | 0.9654 | |
| GSE23400 | FLVCR2 | 55640 | 219316_s_at | 0.0731 | 0.1160 | |
| GSE26886 | FLVCR2 | 55640 | 222866_s_at | -0.5010 | 0.0816 | |
| GSE29001 | FLVCR2 | 55640 | 219316_s_at | 0.1385 | 0.5524 | |
| GSE38129 | FLVCR2 | 55640 | 219316_s_at | 0.0891 | 0.6221 | |
| GSE45670 | FLVCR2 | 55640 | 219316_s_at | 1.0840 | 0.0006 | |
| GSE53622 | FLVCR2 | 55640 | 14084 | 0.5751 | 0.0006 | |
| GSE53624 | FLVCR2 | 55640 | 14084 | 0.1395 | 0.4575 | |
| GSE63941 | FLVCR2 | 55640 | 222866_s_at | 0.4620 | 0.2423 | |
| GSE77861 | FLVCR2 | 55640 | 222866_s_at | -0.0989 | 0.4911 | |
| GSE97050 | FLVCR2 | 55640 | A_23_P140373 | 0.3401 | 0.3085 | |
| SRP007169 | FLVCR2 | 55640 | RNAseq | -0.6527 | 0.3815 | |
| SRP008496 | FLVCR2 | 55640 | RNAseq | -1.3295 | 0.0133 | |
| SRP064894 | FLVCR2 | 55640 | RNAseq | 0.9112 | 0.0005 | |
| SRP133303 | FLVCR2 | 55640 | RNAseq | 0.5068 | 0.0580 | |
| SRP159526 | FLVCR2 | 55640 | RNAseq | -0.0579 | 0.9113 | |
| SRP193095 | FLVCR2 | 55640 | RNAseq | -0.5366 | 0.0425 | |
| SRP219564 | FLVCR2 | 55640 | RNAseq | 1.2033 | 0.0228 | |
| TCGA | FLVCR2 | 55640 | RNAseq | 0.8253 | 0.0000 |
Upregulated datasets: 2; Downregulated datasets: 1.
Survival by FLVCR2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FLVCR2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FLVCR2 | 55640 | 8 | 3 | 19 | |
| GSE20123 | FLVCR2 | 55640 | 8 | 3 | 19 | |
| GSE43470 | FLVCR2 | 55640 | 8 | 3 | 32 | |
| GSE46452 | FLVCR2 | 55640 | 16 | 3 | 40 | |
| GSE47630 | FLVCR2 | 55640 | 11 | 8 | 21 | |
| GSE54993 | FLVCR2 | 55640 | 3 | 8 | 59 | |
| GSE54994 | FLVCR2 | 55640 | 19 | 4 | 30 | |
| GSE60625 | FLVCR2 | 55640 | 0 | 2 | 9 | |
| GSE74703 | FLVCR2 | 55640 | 7 | 3 | 26 | |
| GSE74704 | FLVCR2 | 55640 | 3 | 3 | 14 | |
| TCGA | FLVCR2 | 55640 | 32 | 16 | 48 |
Total number of gains: 115; Total number of losses: 56; Total Number of normals: 317.
Somatic mutations of FLVCR2:
Generating mutation plots.
Highly correlated genes for FLVCR2:
Showing top 20/179 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FLVCR2 | CYP2B6 | 0.70717 | 3 | 0 | 3 |
| FLVCR2 | ZGPAT | 0.705587 | 3 | 0 | 3 |
| FLVCR2 | TTC26 | 0.693142 | 3 | 0 | 3 |
| FLVCR2 | HELB | 0.690459 | 4 | 0 | 3 |
| FLVCR2 | NIPAL4 | 0.688208 | 3 | 0 | 3 |
| FLVCR2 | EIF2S1 | 0.680751 | 4 | 0 | 4 |
| FLVCR2 | PRCC | 0.67802 | 3 | 0 | 3 |
| FLVCR2 | TMCO6 | 0.665644 | 3 | 0 | 3 |
| FLVCR2 | ARG2 | 0.662301 | 4 | 0 | 3 |
| FLVCR2 | RTN4R | 0.647901 | 4 | 0 | 3 |
| FLVCR2 | FGF11 | 0.64588 | 4 | 0 | 4 |
| FLVCR2 | CSF2RA | 0.6453 | 4 | 0 | 4 |
| FLVCR2 | CTSH | 0.64325 | 3 | 0 | 3 |
| FLVCR2 | TAS2R38 | 0.642122 | 3 | 0 | 3 |
| FLVCR2 | C2orf16 | 0.642038 | 3 | 0 | 3 |
| FLVCR2 | ARSK | 0.64195 | 3 | 0 | 3 |
| FLVCR2 | SLC41A2 | 0.641029 | 3 | 0 | 3 |
| FLVCR2 | TUSC3 | 0.63975 | 3 | 0 | 3 |
| FLVCR2 | KLHL28 | 0.637214 | 3 | 0 | 3 |
| FLVCR2 | ADRM1 | 0.635664 | 4 | 0 | 4 |
For details and further investigation, click here
