| Full name: G protein-coupled receptor 75 | Alias Symbol: WI-31133 | ||
| Type: protein-coding gene | Cytoband: 2p16.2 | ||
| Entrez ID: 10936 | HGNC ID: HGNC:4526 | Ensembl Gene: ENSG00000119737 | OMIM ID: 606704 |
| Drug and gene relationship at DGIdb | |||
Expression of GPR75:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GPR75 | 10936 | 220481_at | -0.1934 | 0.4276 | |
| GSE20347 | GPR75 | 10936 | 220481_at | -0.0124 | 0.8868 | |
| GSE23400 | GPR75 | 10936 | 220481_at | -0.1229 | 0.0103 | |
| GSE26886 | GPR75 | 10936 | 220481_at | -0.0941 | 0.4639 | |
| GSE29001 | GPR75 | 10936 | 220481_at | -0.0744 | 0.5622 | |
| GSE38129 | GPR75 | 10936 | 220481_at | -0.0588 | 0.4203 | |
| GSE45670 | GPR75 | 10936 | 220481_at | 0.1286 | 0.2460 | |
| GSE53622 | GPR75 | 10936 | 73811 | -0.2210 | 0.0940 | |
| GSE53624 | GPR75 | 10936 | 73811 | -0.3207 | 0.0006 | |
| GSE63941 | GPR75 | 10936 | 220481_at | 0.0327 | 0.8939 | |
| GSE77861 | GPR75 | 10936 | 220481_at | -0.1154 | 0.3702 | |
| GSE97050 | GPR75 | 10936 | A_23_P68234 | -0.1196 | 0.6923 | |
| SRP133303 | GPR75 | 10936 | RNAseq | 0.0577 | 0.7830 | |
| SRP159526 | GPR75 | 10936 | RNAseq | 0.3757 | 0.1941 | |
| SRP193095 | GPR75 | 10936 | RNAseq | 0.9194 | 0.0000 | |
| SRP219564 | GPR75 | 10936 | RNAseq | -0.3497 | 0.4826 | |
| TCGA | GPR75 | 10936 | RNAseq | -0.1813 | 0.1983 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GPR75 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GPR75:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GPR75 | 10936 | 8 | 0 | 22 | |
| GSE20123 | GPR75 | 10936 | 7 | 0 | 23 | |
| GSE43470 | GPR75 | 10936 | 5 | 0 | 38 | |
| GSE46452 | GPR75 | 10936 | 2 | 4 | 53 | |
| GSE47630 | GPR75 | 10936 | 8 | 0 | 32 | |
| GSE54993 | GPR75 | 10936 | 0 | 5 | 65 | |
| GSE54994 | GPR75 | 10936 | 12 | 2 | 39 | |
| GSE60625 | GPR75 | 10936 | 0 | 3 | 8 | |
| GSE74703 | GPR75 | 10936 | 5 | 0 | 31 | |
| GSE74704 | GPR75 | 10936 | 8 | 0 | 12 | |
| TCGA | GPR75 | 10936 | 36 | 2 | 58 |
Total number of gains: 91; Total number of losses: 16; Total Number of normals: 381.
Somatic mutations of GPR75:
Generating mutation plots.
Highly correlated genes for GPR75:
Showing top 20/391 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GPR75 | JUNB | 0.714066 | 3 | 0 | 3 |
| GPR75 | MTAP | 0.66905 | 4 | 0 | 4 |
| GPR75 | NR0B2 | 0.663526 | 3 | 0 | 3 |
| GPR75 | LINC01210 | 0.661976 | 3 | 0 | 3 |
| GPR75 | PRR32 | 0.651967 | 4 | 0 | 4 |
| GPR75 | NPY2R | 0.640463 | 3 | 0 | 3 |
| GPR75 | NMUR2 | 0.628569 | 3 | 0 | 3 |
| GPR75 | NCR2 | 0.623035 | 5 | 0 | 5 |
| GPR75 | ATP1B2 | 0.618659 | 4 | 0 | 3 |
| GPR75 | SLC2A2 | 0.616973 | 4 | 0 | 4 |
| GPR75 | GRM7 | 0.61585 | 6 | 0 | 4 |
| GPR75 | CRLF2 | 0.615055 | 5 | 0 | 3 |
| GPR75 | DCC | 0.614708 | 4 | 0 | 3 |
| GPR75 | SLC6A5 | 0.612493 | 3 | 0 | 3 |
| GPR75 | OR12D2 | 0.611349 | 7 | 0 | 6 |
| GPR75 | INO80D | 0.611071 | 5 | 0 | 5 |
| GPR75 | MESP1 | 0.609744 | 3 | 0 | 3 |
| GPR75 | FUT9 | 0.607132 | 3 | 0 | 3 |
| GPR75 | LINC00343 | 0.606564 | 3 | 0 | 3 |
| GPR75 | GABRD | 0.606403 | 4 | 0 | 3 |
For details and further investigation, click here
