EEF1E1

 

Full name: eukaryotic translation elongation factor 1 epsilon 1 Alias Symbol: AIMP3
Type: protein-coding gene Cytoband: 6p24.3
Entrez ID: 9521 HGNC ID: HGNC:3212 Ensembl Gene: ENSG00000124802 OMIM ID: 609206
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of EEF1E1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 EEF1E1 9521 204905_s_at 0.3925 0.3089
GSE20347 EEF1E1 9521 204905_s_at 0.6403 0.0177
GSE23400 EEF1E1 9521 204905_s_at 0.9007 0.0000
GSE26886 EEF1E1 9521 204905_s_at 0.8730 0.0010
GSE29001 EEF1E1 9521 204905_s_at 0.6217 0.1149
GSE38129 EEF1E1 9521 204905_s_at 0.7666 0.0000
GSE45670 EEF1E1 9521 204905_s_at 0.3288 0.1066
GSE63941 EEF1E1 9521 204905_s_at 1.0001 0.0018
GSE77861 EEF1E1 9521 204905_s_at 0.2893 0.3947
GSE97050 EEF1E1 9521 A_23_P156842 0.7012 0.1836
SRP007169 EEF1E1 9521 RNAseq 0.2526 0.5245
SRP008496 EEF1E1 9521 RNAseq 0.2070 0.5292
SRP064894 EEF1E1 9521 RNAseq 0.1101 0.5812
SRP133303 EEF1E1 9521 RNAseq 0.6899 0.0045
SRP159526 EEF1E1 9521 RNAseq 0.7105 0.0004
SRP193095 EEF1E1 9521 RNAseq -0.1607 0.2242
SRP219564 EEF1E1 9521 RNAseq -0.0160 0.9548
TCGA EEF1E1 9521 RNAseq 0.0939 0.2092

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by EEF1E1 expression:

 

TCGA

 

Note: Click image to view full size file.  

Copy number change of EEF1E1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 EEF1E1 9521 3 6 21
GSE20123 EEF1E1 9521 3 6 21
GSE43470 EEF1E1 9521 8 2 33
GSE46452 EEF1E1 9521 1 10 48
GSE47630 EEF1E1 9521 7 8 25
GSE54993 EEF1E1 9521 1 1 68
GSE54994 EEF1E1 9521 10 3 40
GSE60625 EEF1E1 9521 0 1 10
GSE74703 EEF1E1 9521 7 2 27
GSE74704 EEF1E1 9521 2 2 16
TCGA EEF1E1 9521 15 29 52

Total number of gains: 57; Total number of losses: 70; Total Number of normals: 361.  

 

Somatic mutations of EEF1E1:

 

Generating mutation plots.

 

Highly correlated genes for EEF1E1:

 

Showing top 20/1293 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
EEF1E1RRP360.762069505
EEF1E1RAD180.752618303
EEF1E1CTU20.750821303
EEF1E1ELOF10.727047303
EEF1E1SNRPC0.72447410010
EEF1E1NOL70.72428611010
EEF1E1RPAP30.721603908
EEF1E1AP1S30.709408303
EEF1E1LYRM40.70270410010
EEF1E1UMPS0.701182908
EEF1E1CTPS10.700503707
EEF1E1DMTF10.697828303
EEF1E1PPIL40.697134303
EEF1E1PPIL10.692178707
EEF1E1GMNN0.69188511010
EEF1E1MRPL30.6899051009
EEF1E1PFAS0.689801807
EEF1E1ANGPT20.689613303
EEF1E1DBF40.689277909
EEF1E1DEK0.68815411010

For details and further investigation, click here