| Full name: tRNA methyltransferase 10C, mitochondrial RNase P subunit | Alias Symbol: FLJ20432|MRPP1 | ||
| Type: protein-coding gene | Cytoband: 3q12.3 | ||
| Entrez ID: 54931 | HGNC ID: HGNC:26022 | Ensembl Gene: ENSG00000174173 | OMIM ID: 615423 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of TRMT10C:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TRMT10C | 54931 | 223267_at | 0.7660 | 0.1046 | |
| GSE26886 | TRMT10C | 54931 | 223267_at | 0.5902 | 0.0130 | |
| GSE45670 | TRMT10C | 54931 | 223267_at | 0.4972 | 0.0106 | |
| GSE53622 | TRMT10C | 54931 | 37079 | 0.3634 | 0.0000 | |
| GSE53624 | TRMT10C | 54931 | 37079 | 0.6535 | 0.0000 | |
| GSE63941 | TRMT10C | 54931 | 223267_at | 0.7413 | 0.1097 | |
| GSE77861 | TRMT10C | 54931 | 223267_at | 0.1673 | 0.6115 | |
| SRP007169 | TRMT10C | 54931 | RNAseq | 0.1004 | 0.8034 | |
| SRP008496 | TRMT10C | 54931 | RNAseq | 0.2444 | 0.3184 | |
| SRP064894 | TRMT10C | 54931 | RNAseq | 0.0806 | 0.6857 | |
| SRP133303 | TRMT10C | 54931 | RNAseq | 0.2190 | 0.3013 | |
| SRP159526 | TRMT10C | 54931 | RNAseq | 0.2675 | 0.4137 | |
| SRP193095 | TRMT10C | 54931 | RNAseq | 0.1950 | 0.2287 | |
| SRP219564 | TRMT10C | 54931 | RNAseq | 0.0668 | 0.8649 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TRMT10C expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of TRMT10C:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TRMT10C | 54931 | 18 | 1 | 11 | |
| GSE20123 | TRMT10C | 54931 | 17 | 1 | 12 | |
| GSE43470 | TRMT10C | 54931 | 17 | 1 | 25 | |
| GSE46452 | TRMT10C | 54931 | 12 | 6 | 41 | |
| GSE47630 | TRMT10C | 54931 | 16 | 6 | 18 | |
| GSE54993 | TRMT10C | 54931 | 2 | 5 | 63 | |
| GSE54994 | TRMT10C | 54931 | 27 | 5 | 21 | |
| GSE60625 | TRMT10C | 54931 | 0 | 6 | 5 | |
| GSE74703 | TRMT10C | 54931 | 14 | 1 | 21 | |
| GSE74704 | TRMT10C | 54931 | 14 | 1 | 5 | |
| TCGA | TRMT10C | 54931 | 48 | 9 | 39 |
Total number of gains: 185; Total number of losses: 42; Total Number of normals: 261.
Somatic mutations of TRMT10C:
Generating mutation plots.
Highly correlated genes for TRMT10C:
Showing top 20/577 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TRMT10C | BPNT1 | 0.780656 | 3 | 0 | 3 |
| TRMT10C | MTERF3 | 0.750685 | 3 | 0 | 3 |
| TRMT10C | FBRSL1 | 0.726431 | 3 | 0 | 3 |
| TRMT10C | ZNF184 | 0.719661 | 3 | 0 | 3 |
| TRMT10C | NOL7 | 0.713536 | 4 | 0 | 4 |
| TRMT10C | DCAF13 | 0.70184 | 5 | 0 | 5 |
| TRMT10C | DNLZ | 0.699738 | 3 | 0 | 3 |
| TRMT10C | CMSS1 | 0.694585 | 7 | 0 | 7 |
| TRMT10C | UMPS | 0.69442 | 6 | 0 | 5 |
| TRMT10C | NIT2 | 0.693792 | 6 | 0 | 6 |
| TRMT10C | HOMER1 | 0.692763 | 3 | 0 | 3 |
| TRMT10C | RPN1 | 0.692604 | 5 | 0 | 5 |
| TRMT10C | ZNF148 | 0.689827 | 3 | 0 | 3 |
| TRMT10C | DDX51 | 0.6896 | 3 | 0 | 3 |
| TRMT10C | URB2 | 0.688981 | 5 | 0 | 5 |
| TRMT10C | TMEM248 | 0.679239 | 3 | 0 | 3 |
| TRMT10C | DNAJC2 | 0.676334 | 5 | 0 | 5 |
| TRMT10C | CCDC86 | 0.67388 | 3 | 0 | 3 |
| TRMT10C | MTBP | 0.670348 | 4 | 0 | 4 |
| TRMT10C | NAA50 | 0.667884 | 5 | 0 | 4 |
For details and further investigation, click here
