| Full name: neuropeptide B | Alias Symbol: PPL7|PPNPB | ||
| Type: protein-coding gene | Cytoband: 17q25.3 | ||
| Entrez ID: 256933 | HGNC ID: HGNC:30099 | Ensembl Gene: ENSG00000183979 | OMIM ID: 607996 |
| Drug and gene relationship at DGIdb | |||
Expression of NPB:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NPB | 256933 | 1553663_a_at | 0.1224 | 0.6462 | |
| GSE26886 | NPB | 256933 | 1553663_a_at | 0.5032 | 0.0054 | |
| GSE45670 | NPB | 256933 | 1553663_a_at | 0.1434 | 0.2028 | |
| GSE63941 | NPB | 256933 | 1553663_a_at | 0.1210 | 0.4876 | |
| GSE77861 | NPB | 256933 | 1553663_a_at | 0.0485 | 0.8236 | |
| GSE97050 | NPB | 256933 | A_33_P3419970 | -0.1260 | 0.6575 | |
| TCGA | NPB | 256933 | RNAseq | 0.5202 | 0.0308 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NPB expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of NPB:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NPB | 256933 | 4 | 4 | 22 | |
| GSE20123 | NPB | 256933 | 4 | 4 | 22 | |
| GSE43470 | NPB | 256933 | 3 | 5 | 35 | |
| GSE46452 | NPB | 256933 | 34 | 0 | 25 | |
| GSE47630 | NPB | 256933 | 9 | 2 | 29 | |
| GSE54993 | NPB | 256933 | 2 | 5 | 63 | |
| GSE54994 | NPB | 256933 | 10 | 6 | 37 | |
| GSE60625 | NPB | 256933 | 6 | 0 | 5 | |
| GSE74703 | NPB | 256933 | 3 | 3 | 30 | |
| GSE74704 | NPB | 256933 | 4 | 3 | 13 | |
| TCGA | NPB | 256933 | 25 | 12 | 59 |
Total number of gains: 104; Total number of losses: 44; Total Number of normals: 340.
Somatic mutations of NPB:
Generating mutation plots.
Highly correlated genes for NPB:
Showing top 20/142 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NPB | EVI5L | 0.714878 | 3 | 0 | 3 |
| NPB | TNFRSF10C | 0.714502 | 3 | 0 | 3 |
| NPB | CD101 | 0.712561 | 3 | 0 | 3 |
| NPB | ITPK1 | 0.698444 | 3 | 0 | 3 |
| NPB | IL17C | 0.692586 | 3 | 0 | 3 |
| NPB | CEACAM4 | 0.67616 | 3 | 0 | 3 |
| NPB | CD151 | 0.675657 | 3 | 0 | 3 |
| NPB | SMARCD1 | 0.674343 | 3 | 0 | 3 |
| NPB | SLC12A4 | 0.671572 | 3 | 0 | 3 |
| NPB | NLGN2 | 0.668746 | 3 | 0 | 3 |
| NPB | CSF3R | 0.668682 | 4 | 0 | 3 |
| NPB | FGF16 | 0.668496 | 3 | 0 | 3 |
| NPB | GAMT | 0.667068 | 4 | 0 | 3 |
| NPB | FHOD3 | 0.660406 | 3 | 0 | 3 |
| NPB | TAF6 | 0.660275 | 3 | 0 | 3 |
| NPB | EHD2 | 0.659916 | 4 | 0 | 4 |
| NPB | SLC6A20 | 0.657999 | 3 | 0 | 3 |
| NPB | LINC01364 | 0.653974 | 3 | 0 | 3 |
| NPB | WNT10A | 0.652205 | 3 | 0 | 3 |
| NPB | NALCN-AS1 | 0.651554 | 3 | 0 | 3 |
For details and further investigation, click here
