| Full name: interleukin 17C | Alias Symbol: IL-17C|CX2|IL-21|MGC126884|MGC138401 | ||
| Type: protein-coding gene | Cytoband: 16q24.2 | ||
| Entrez ID: 27189 | HGNC ID: HGNC:5983 | Ensembl Gene: ENSG00000124391 | OMIM ID: 604628 |
| Drug and gene relationship at DGIdb | |||
Expression of IL17C:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IL17C | 27189 | 224079_at | 0.1083 | 0.7170 | |
| GSE26886 | IL17C | 27189 | 224079_at | 0.1836 | 0.2304 | |
| GSE45670 | IL17C | 27189 | 224079_at | 0.2243 | 0.0144 | |
| GSE53622 | IL17C | 27189 | 97016 | 0.5217 | 0.0196 | |
| GSE53624 | IL17C | 27189 | 97016 | 0.6380 | 0.0075 | |
| GSE63941 | IL17C | 27189 | 224079_at | 0.6499 | 0.0001 | |
| GSE77861 | IL17C | 27189 | 224079_at | 0.0383 | 0.8231 | |
| TCGA | IL17C | 27189 | RNAseq | 1.8978 | 0.0209 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by IL17C expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IL17C:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IL17C | 27189 | 4 | 3 | 23 | |
| GSE20123 | IL17C | 27189 | 4 | 3 | 23 | |
| GSE43470 | IL17C | 27189 | 1 | 13 | 29 | |
| GSE46452 | IL17C | 27189 | 38 | 1 | 20 | |
| GSE47630 | IL17C | 27189 | 11 | 9 | 20 | |
| GSE54993 | IL17C | 27189 | 3 | 4 | 63 | |
| GSE54994 | IL17C | 27189 | 9 | 11 | 33 | |
| GSE60625 | IL17C | 27189 | 4 | 0 | 7 | |
| GSE74703 | IL17C | 27189 | 1 | 9 | 26 | |
| GSE74704 | IL17C | 27189 | 3 | 2 | 15 | |
| TCGA | IL17C | 27189 | 28 | 15 | 53 |
Total number of gains: 106; Total number of losses: 70; Total Number of normals: 312.
Somatic mutations of IL17C:
Generating mutation plots.
Highly correlated genes for IL17C:
Showing top 20/164 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IL17C | GIGYF1 | 0.716401 | 4 | 0 | 4 |
| IL17C | GIT1 | 0.701164 | 3 | 0 | 3 |
| IL17C | NPB | 0.692586 | 3 | 0 | 3 |
| IL17C | PNPLA2 | 0.684519 | 3 | 0 | 3 |
| IL17C | EPX | 0.680115 | 3 | 0 | 3 |
| IL17C | CABP4 | 0.676946 | 4 | 0 | 4 |
| IL17C | LTK | 0.663985 | 3 | 0 | 3 |
| IL17C | FBXO27 | 0.659944 | 3 | 0 | 3 |
| IL17C | HMX1 | 0.65882 | 3 | 0 | 3 |
| IL17C | NIT1 | 0.649146 | 4 | 0 | 4 |
| IL17C | ELAVL3 | 0.647993 | 3 | 0 | 3 |
| IL17C | VPS9D1-AS1 | 0.646403 | 4 | 0 | 3 |
| IL17C | ASPDH | 0.63935 | 3 | 0 | 3 |
| IL17C | ADRB3 | 0.636962 | 4 | 0 | 4 |
| IL17C | PPP1R9B | 0.636836 | 4 | 0 | 4 |
| IL17C | GGN | 0.633337 | 4 | 0 | 4 |
| IL17C | KLF16 | 0.630815 | 4 | 0 | 3 |
| IL17C | DLG5-AS1 | 0.63079 | 4 | 0 | 3 |
| IL17C | SEZ6L2 | 0.628937 | 3 | 0 | 3 |
| IL17C | NFKBID | 0.627787 | 5 | 0 | 4 |
For details and further investigation, click here
