| Full name: neuropeptide FF-amide peptide precursor | Alias Symbol: FMRFAL | ||
| Type: protein-coding gene | Cytoband: 12q13.13 | ||
| Entrez ID: 8620 | HGNC ID: HGNC:7901 | Ensembl Gene: ENSG00000139574 | OMIM ID: 604643 |
| Drug and gene relationship at DGIdb | |||
Expression of NPFF:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NPFF | 8620 | 206402_s_at | 0.0730 | 0.8162 | |
| GSE20347 | NPFF | 8620 | 206402_s_at | 0.0179 | 0.8609 | |
| GSE23400 | NPFF | 8620 | 214184_at | 0.0909 | 0.0651 | |
| GSE26886 | NPFF | 8620 | 206402_s_at | 0.0841 | 0.5149 | |
| GSE29001 | NPFF | 8620 | 206402_s_at | -0.0994 | 0.6789 | |
| GSE38129 | NPFF | 8620 | 206402_s_at | -0.1674 | 0.0472 | |
| GSE45670 | NPFF | 8620 | 206402_s_at | 0.1108 | 0.3393 | |
| GSE63941 | NPFF | 8620 | 206402_s_at | 0.0363 | 0.8907 | |
| GSE77861 | NPFF | 8620 | 206402_s_at | 0.0196 | 0.9230 | |
| GSE97050 | NPFF | 8620 | A_23_P204079 | -0.0359 | 0.8793 | |
| SRP064894 | NPFF | 8620 | RNAseq | 0.4566 | 0.0662 | |
| SRP133303 | NPFF | 8620 | RNAseq | -0.2930 | 0.2656 | |
| SRP159526 | NPFF | 8620 | RNAseq | -0.1381 | 0.8215 | |
| SRP219564 | NPFF | 8620 | RNAseq | 0.1621 | 0.7691 | |
| TCGA | NPFF | 8620 | RNAseq | -0.2224 | 0.3499 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NPFF expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of NPFF:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NPFF | 8620 | 7 | 1 | 22 | |
| GSE20123 | NPFF | 8620 | 7 | 1 | 22 | |
| GSE43470 | NPFF | 8620 | 3 | 0 | 40 | |
| GSE46452 | NPFF | 8620 | 7 | 1 | 51 | |
| GSE47630 | NPFF | 8620 | 10 | 2 | 28 | |
| GSE54993 | NPFF | 8620 | 0 | 5 | 65 | |
| GSE54994 | NPFF | 8620 | 4 | 1 | 48 | |
| GSE60625 | NPFF | 8620 | 0 | 0 | 11 | |
| GSE74703 | NPFF | 8620 | 3 | 0 | 33 | |
| GSE74704 | NPFF | 8620 | 5 | 1 | 14 | |
| TCGA | NPFF | 8620 | 14 | 11 | 71 |
Total number of gains: 60; Total number of losses: 23; Total Number of normals: 405.
Somatic mutations of NPFF:
Generating mutation plots.
Highly correlated genes for NPFF:
Showing top 20/539 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NPFF | NCDN | 0.804458 | 4 | 0 | 4 |
| NPFF | SZT2 | 0.802531 | 3 | 0 | 3 |
| NPFF | TRPM6 | 0.788323 | 3 | 0 | 3 |
| NPFF | USP19 | 0.774488 | 3 | 0 | 3 |
| NPFF | ZNF513 | 0.764062 | 3 | 0 | 3 |
| NPFF | EMD | 0.756798 | 3 | 0 | 3 |
| NPFF | NUCB1 | 0.751491 | 3 | 0 | 3 |
| NPFF | SCML4 | 0.750032 | 3 | 0 | 3 |
| NPFF | PRPS1L1 | 0.748476 | 4 | 0 | 4 |
| NPFF | ZBTB22 | 0.72969 | 3 | 0 | 3 |
| NPFF | ZNF287 | 0.727439 | 3 | 0 | 3 |
| NPFF | MID1IP1 | 0.723555 | 3 | 0 | 3 |
| NPFF | CYHR1 | 0.723247 | 4 | 0 | 4 |
| NPFF | C8orf44 | 0.722187 | 3 | 0 | 3 |
| NPFF | ZNF419 | 0.72162 | 3 | 0 | 3 |
| NPFF | NGF | 0.720634 | 3 | 0 | 3 |
| NPFF | C19orf47 | 0.715975 | 3 | 0 | 3 |
| NPFF | FBXO31 | 0.713458 | 5 | 0 | 4 |
| NPFF | CDK5RAP3 | 0.712892 | 3 | 0 | 3 |
| NPFF | RPRD2 | 0.712283 | 3 | 0 | 3 |
For details and further investigation, click here
