| Full name: Scm polycomb group protein like 4 | Alias Symbol: dJ47M23.1 | ||
| Type: protein-coding gene | Cytoband: 6q21 | ||
| Entrez ID: 256380 | HGNC ID: HGNC:21397 | Ensembl Gene: ENSG00000146285 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of SCML4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SCML4 | 256380 | 1556472_s_at | 0.1346 | 0.8439 | |
| GSE26886 | SCML4 | 256380 | 1556472_s_at | -0.2332 | 0.1443 | |
| GSE45670 | SCML4 | 256380 | 1563542_a_at | -0.0054 | 0.9612 | |
| GSE63941 | SCML4 | 256380 | 1563542_a_at | 0.1851 | 0.2994 | |
| GSE77861 | SCML4 | 256380 | 1563542_a_at | -0.0910 | 0.3359 | |
| GSE97050 | SCML4 | 256380 | A_33_P3387691 | 0.1369 | 0.5703 | |
| SRP064894 | SCML4 | 256380 | RNAseq | -1.3923 | 0.0000 | |
| SRP133303 | SCML4 | 256380 | RNAseq | -0.6291 | 0.0000 | |
| SRP159526 | SCML4 | 256380 | RNAseq | -1.4234 | 0.0011 | |
| SRP193095 | SCML4 | 256380 | RNAseq | -0.3660 | 0.0334 | |
| SRP219564 | SCML4 | 256380 | RNAseq | -0.7510 | 0.1754 | |
| TCGA | SCML4 | 256380 | RNAseq | -0.9963 | 0.0278 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by SCML4 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of SCML4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SCML4 | 256380 | 2 | 3 | 25 | |
| GSE20123 | SCML4 | 256380 | 2 | 2 | 26 | |
| GSE43470 | SCML4 | 256380 | 3 | 1 | 39 | |
| GSE46452 | SCML4 | 256380 | 2 | 11 | 46 | |
| GSE47630 | SCML4 | 256380 | 9 | 4 | 27 | |
| GSE54993 | SCML4 | 256380 | 3 | 2 | 65 | |
| GSE54994 | SCML4 | 256380 | 8 | 8 | 37 | |
| GSE60625 | SCML4 | 256380 | 0 | 2 | 9 | |
| GSE74703 | SCML4 | 256380 | 2 | 1 | 33 | |
| GSE74704 | SCML4 | 256380 | 0 | 0 | 20 | |
| TCGA | SCML4 | 256380 | 5 | 23 | 68 |
Total number of gains: 36; Total number of losses: 57; Total Number of normals: 395.
Somatic mutations of SCML4:
Generating mutation plots.
Highly correlated genes for SCML4:
Showing top 20/146 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SCML4 | PTPN7 | 0.795002 | 3 | 0 | 3 |
| SCML4 | ACSL1 | 0.792617 | 3 | 0 | 3 |
| SCML4 | CDK5RAP3 | 0.791229 | 3 | 0 | 3 |
| SCML4 | KLRC3 | 0.776141 | 3 | 0 | 3 |
| SCML4 | BTN2A2 | 0.774137 | 3 | 0 | 3 |
| SCML4 | SPIC | 0.768704 | 3 | 0 | 3 |
| SCML4 | ZNF419 | 0.759868 | 3 | 0 | 3 |
| SCML4 | NPFF | 0.750032 | 3 | 0 | 3 |
| SCML4 | ARHGEF16 | 0.735846 | 3 | 0 | 3 |
| SCML4 | IRF8 | 0.729456 | 3 | 0 | 3 |
| SCML4 | XYLB | 0.727194 | 3 | 0 | 3 |
| SCML4 | GIMAP7 | 0.724479 | 3 | 0 | 3 |
| SCML4 | HERC6 | 0.723597 | 3 | 0 | 3 |
| SCML4 | C16orf54 | 0.723445 | 3 | 0 | 3 |
| SCML4 | NKG7 | 0.723058 | 4 | 0 | 4 |
| SCML4 | PTPN22 | 0.721587 | 3 | 0 | 3 |
| SCML4 | METTL14 | 0.717526 | 3 | 0 | 3 |
| SCML4 | GAB3 | 0.715424 | 3 | 0 | 3 |
| SCML4 | IMMP1L | 0.713112 | 3 | 0 | 3 |
| SCML4 | LY6E | 0.708512 | 3 | 0 | 3 |
For details and further investigation, click here
