| Full name: regulation of nuclear pre-mRNA domain containing 2 | Alias Symbol: FLJ32145|HSPC099 | ||
| Type: protein-coding gene | Cytoband: 1q21.2 | ||
| Entrez ID: 23248 | HGNC ID: HGNC:29039 | Ensembl Gene: ENSG00000163125 | OMIM ID: 614695 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of RPRD2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RPRD2 | 23248 | 212553_at | 0.2620 | 0.6694 | |
| GSE20347 | RPRD2 | 23248 | 212553_at | 0.1735 | 0.0966 | |
| GSE23400 | RPRD2 | 23248 | 212553_at | 0.0484 | 0.3642 | |
| GSE26886 | RPRD2 | 23248 | 212553_at | 0.0893 | 0.5556 | |
| GSE29001 | RPRD2 | 23248 | 212553_at | -0.0867 | 0.7523 | |
| GSE38129 | RPRD2 | 23248 | 212553_at | -0.0150 | 0.9049 | |
| GSE45670 | RPRD2 | 23248 | 212553_at | 0.0259 | 0.8941 | |
| GSE53622 | RPRD2 | 23248 | 125538 | 0.0005 | 0.9933 | |
| GSE53624 | RPRD2 | 23248 | 125538 | 0.0456 | 0.4729 | |
| GSE63941 | RPRD2 | 23248 | 212553_at | 1.4252 | 0.0003 | |
| GSE77861 | RPRD2 | 23248 | 212553_at | 0.0700 | 0.6994 | |
| GSE97050 | RPRD2 | 23248 | A_23_P60657 | -0.4844 | 0.2261 | |
| SRP007169 | RPRD2 | 23248 | RNAseq | -0.4760 | 0.2144 | |
| SRP008496 | RPRD2 | 23248 | RNAseq | -0.2635 | 0.2470 | |
| SRP064894 | RPRD2 | 23248 | RNAseq | -0.6020 | 0.0001 | |
| SRP133303 | RPRD2 | 23248 | RNAseq | -0.0292 | 0.8028 | |
| SRP159526 | RPRD2 | 23248 | RNAseq | 0.1399 | 0.5111 | |
| SRP193095 | RPRD2 | 23248 | RNAseq | -0.0833 | 0.4089 | |
| SRP219564 | RPRD2 | 23248 | RNAseq | -0.1051 | 0.7069 | |
| TCGA | RPRD2 | 23248 | RNAseq | 0.0072 | 0.8675 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by RPRD2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RPRD2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RPRD2 | 23248 | 15 | 0 | 15 | |
| GSE20123 | RPRD2 | 23248 | 15 | 0 | 15 | |
| GSE43470 | RPRD2 | 23248 | 6 | 1 | 36 | |
| GSE46452 | RPRD2 | 23248 | 2 | 1 | 56 | |
| GSE47630 | RPRD2 | 23248 | 14 | 0 | 26 | |
| GSE54993 | RPRD2 | 23248 | 0 | 3 | 67 | |
| GSE54994 | RPRD2 | 23248 | 15 | 0 | 38 | |
| GSE60625 | RPRD2 | 23248 | 0 | 0 | 11 | |
| GSE74703 | RPRD2 | 23248 | 6 | 1 | 29 | |
| GSE74704 | RPRD2 | 23248 | 7 | 0 | 13 | |
| TCGA | RPRD2 | 23248 | 38 | 2 | 56 |
Total number of gains: 118; Total number of losses: 8; Total Number of normals: 362.
Somatic mutations of RPRD2:
Generating mutation plots.
Highly correlated genes for RPRD2:
Showing top 20/336 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RPRD2 | SCAF1 | 0.841114 | 3 | 0 | 3 |
| RPRD2 | VEGFB | 0.807543 | 3 | 0 | 3 |
| RPRD2 | MAP3K13 | 0.752499 | 3 | 0 | 3 |
| RPRD2 | ZFP3 | 0.735866 | 3 | 0 | 3 |
| RPRD2 | BCORL1 | 0.732845 | 3 | 0 | 3 |
| RPRD2 | TMEM115 | 0.732634 | 3 | 0 | 3 |
| RPRD2 | MAST2 | 0.730788 | 3 | 0 | 3 |
| RPRD2 | NBPF1 | 0.726467 | 3 | 0 | 3 |
| RPRD2 | NR1H2 | 0.725547 | 4 | 0 | 4 |
| RPRD2 | TRAPPC1 | 0.723606 | 3 | 0 | 3 |
| RPRD2 | INTS7 | 0.719334 | 3 | 0 | 3 |
| RPRD2 | ZNF784 | 0.717615 | 3 | 0 | 3 |
| RPRD2 | KRTCAP2 | 0.716329 | 3 | 0 | 3 |
| RPRD2 | TAF3 | 0.71431 | 3 | 0 | 3 |
| RPRD2 | NPFF | 0.712283 | 3 | 0 | 3 |
| RPRD2 | RSBN1L | 0.710342 | 3 | 0 | 3 |
| RPRD2 | SHISA5 | 0.709589 | 3 | 0 | 3 |
| RPRD2 | CA11 | 0.707027 | 3 | 0 | 3 |
| RPRD2 | C2orf76 | 0.706508 | 3 | 0 | 3 |
| RPRD2 | STRBP | 0.705978 | 3 | 0 | 3 |
For details and further investigation, click here
