| Full name: neurochondrin | Alias Symbol: NCDN-1|NCDN-2 | ||
| Type: protein-coding gene | Cytoband: 1p34.3 | ||
| Entrez ID: 23154 | HGNC ID: HGNC:17597 | Ensembl Gene: ENSG00000020129 | OMIM ID: 608458 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of NCDN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NCDN | 23154 | 209556_at | 0.4599 | 0.1946 | |
| GSE20347 | NCDN | 23154 | 209556_at | 0.4090 | 0.0003 | |
| GSE23400 | NCDN | 23154 | 209556_at | 0.3471 | 0.0000 | |
| GSE26886 | NCDN | 23154 | 209557_s_at | 0.2807 | 0.0134 | |
| GSE29001 | NCDN | 23154 | 209557_s_at | -0.0325 | 0.9020 | |
| GSE38129 | NCDN | 23154 | 209556_at | 0.2415 | 0.0288 | |
| GSE45670 | NCDN | 23154 | 209557_s_at | 0.1476 | 0.1164 | |
| GSE53622 | NCDN | 23154 | 123225 | 0.4575 | 0.0000 | |
| GSE53624 | NCDN | 23154 | 123225 | 0.9081 | 0.0000 | |
| GSE63941 | NCDN | 23154 | 209557_s_at | 0.3307 | 0.1388 | |
| GSE77861 | NCDN | 23154 | 209557_s_at | 0.0016 | 0.9921 | |
| GSE97050 | NCDN | 23154 | A_23_P97736 | -0.1558 | 0.6361 | |
| SRP007169 | NCDN | 23154 | RNAseq | 0.5498 | 0.2087 | |
| SRP008496 | NCDN | 23154 | RNAseq | 0.5916 | 0.0492 | |
| SRP064894 | NCDN | 23154 | RNAseq | 0.8533 | 0.0000 | |
| SRP133303 | NCDN | 23154 | RNAseq | 0.4223 | 0.0117 | |
| SRP159526 | NCDN | 23154 | RNAseq | 0.5659 | 0.0602 | |
| SRP193095 | NCDN | 23154 | RNAseq | 0.7744 | 0.0000 | |
| SRP219564 | NCDN | 23154 | RNAseq | 0.2501 | 0.5496 | |
| TCGA | NCDN | 23154 | RNAseq | -0.0589 | 0.2957 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NCDN expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NCDN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NCDN | 23154 | 2 | 5 | 23 | |
| GSE20123 | NCDN | 23154 | 2 | 4 | 24 | |
| GSE43470 | NCDN | 23154 | 7 | 2 | 34 | |
| GSE46452 | NCDN | 23154 | 4 | 1 | 54 | |
| GSE47630 | NCDN | 23154 | 8 | 3 | 29 | |
| GSE54993 | NCDN | 23154 | 1 | 1 | 68 | |
| GSE54994 | NCDN | 23154 | 11 | 2 | 40 | |
| GSE60625 | NCDN | 23154 | 0 | 0 | 11 | |
| GSE74703 | NCDN | 23154 | 6 | 1 | 29 | |
| GSE74704 | NCDN | 23154 | 1 | 0 | 19 | |
| TCGA | NCDN | 23154 | 11 | 19 | 66 |
Total number of gains: 53; Total number of losses: 38; Total Number of normals: 397.
Somatic mutations of NCDN:
Generating mutation plots.
Highly correlated genes for NCDN:
Showing top 20/801 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NCDN | NPFF | 0.804458 | 4 | 0 | 4 |
| NCDN | POLR2A | 0.765032 | 3 | 0 | 3 |
| NCDN | CCDC154 | 0.762072 | 3 | 0 | 3 |
| NCDN | ZNF358 | 0.752617 | 4 | 0 | 3 |
| NCDN | BCORL1 | 0.743551 | 5 | 0 | 4 |
| NCDN | FOXC2 | 0.739402 | 3 | 0 | 3 |
| NCDN | SNTA1 | 0.738364 | 3 | 0 | 3 |
| NCDN | DERL3 | 0.73332 | 3 | 0 | 3 |
| NCDN | ZNF286A | 0.733305 | 3 | 0 | 3 |
| NCDN | CYP2B6 | 0.73148 | 3 | 0 | 3 |
| NCDN | FCHO1 | 0.729983 | 4 | 0 | 4 |
| NCDN | SSC5D | 0.7282 | 3 | 0 | 3 |
| NCDN | KTI12 | 0.726324 | 3 | 0 | 3 |
| NCDN | AGTRAP | 0.724094 | 3 | 0 | 3 |
| NCDN | SLC35B2 | 0.722844 | 3 | 0 | 3 |
| NCDN | SPTAN1 | 0.711814 | 4 | 0 | 4 |
| NCDN | ZNF319 | 0.711222 | 3 | 0 | 3 |
| NCDN | BRAT1 | 0.705908 | 5 | 0 | 4 |
| NCDN | HKDC1 | 0.704767 | 4 | 0 | 4 |
| NCDN | TNPO1 | 0.704157 | 5 | 0 | 4 |
For details and further investigation, click here
