| Full name: cysteine and histidine rich 1 | Alias Symbol: CHRP|KIAA0496|MGC13010 | ||
| Type: protein-coding gene | Cytoband: 8q24.3 | ||
| Entrez ID: 50626 | HGNC ID: HGNC:17806 | Ensembl Gene: ENSG00000187954 | OMIM ID: 616635 |
| Drug and gene relationship at DGIdb | |||
Expression of CYHR1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CYHR1 | 50626 | 223421_at | 0.3552 | 0.3743 | |
| GSE20347 | CYHR1 | 50626 | 213072_at | -0.1172 | 0.2460 | |
| GSE23400 | CYHR1 | 50626 | 213681_at | 0.1023 | 0.0532 | |
| GSE26886 | CYHR1 | 50626 | 223421_at | 0.4605 | 0.0238 | |
| GSE29001 | CYHR1 | 50626 | 213681_at | 0.2534 | 0.2136 | |
| GSE38129 | CYHR1 | 50626 | 213072_at | -0.0884 | 0.2832 | |
| GSE45670 | CYHR1 | 50626 | 223421_at | -0.0046 | 0.9804 | |
| GSE53622 | CYHR1 | 50626 | 60659 | 0.4188 | 0.0000 | |
| GSE53624 | CYHR1 | 50626 | 60659 | 0.1860 | 0.0079 | |
| GSE63941 | CYHR1 | 50626 | 223421_at | -0.2493 | 0.4879 | |
| GSE77861 | CYHR1 | 50626 | 223421_at | 0.0437 | 0.8403 | |
| GSE97050 | CYHR1 | 50626 | A_24_P40978 | 0.0664 | 0.7778 | |
| SRP007169 | CYHR1 | 50626 | RNAseq | -1.0824 | 0.0109 | |
| SRP008496 | CYHR1 | 50626 | RNAseq | -0.4638 | 0.1861 | |
| SRP064894 | CYHR1 | 50626 | RNAseq | 0.7424 | 0.0323 | |
| SRP133303 | CYHR1 | 50626 | RNAseq | -0.0486 | 0.7299 | |
| SRP159526 | CYHR1 | 50626 | RNAseq | 0.1884 | 0.4238 | |
| SRP193095 | CYHR1 | 50626 | RNAseq | 0.2092 | 0.0599 | |
| SRP219564 | CYHR1 | 50626 | RNAseq | 0.3437 | 0.4760 | |
| TCGA | CYHR1 | 50626 | RNAseq | 0.1054 | 0.0676 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by CYHR1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CYHR1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CYHR1 | 50626 | 17 | 1 | 12 | |
| GSE20123 | CYHR1 | 50626 | 17 | 1 | 12 | |
| GSE43470 | CYHR1 | 50626 | 16 | 2 | 25 | |
| GSE46452 | CYHR1 | 50626 | 28 | 0 | 31 | |
| GSE47630 | CYHR1 | 50626 | 25 | 1 | 14 | |
| GSE54993 | CYHR1 | 50626 | 0 | 25 | 45 | |
| GSE54994 | CYHR1 | 50626 | 39 | 1 | 13 | |
| GSE60625 | CYHR1 | 50626 | 3 | 4 | 4 | |
| GSE74703 | CYHR1 | 50626 | 14 | 1 | 21 | |
| GSE74704 | CYHR1 | 50626 | 10 | 0 | 10 | |
| TCGA | CYHR1 | 50626 | 63 | 2 | 31 |
Total number of gains: 232; Total number of losses: 38; Total Number of normals: 218.
Somatic mutations of CYHR1:
Generating mutation plots.
Highly correlated genes for CYHR1:
Showing top 20/538 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CYHR1 | USF2 | 0.833855 | 3 | 0 | 3 |
| CYHR1 | MIER2 | 0.824552 | 3 | 0 | 3 |
| CYHR1 | JTB | 0.821329 | 3 | 0 | 3 |
| CYHR1 | FOXP4 | 0.7851 | 3 | 0 | 3 |
| CYHR1 | RPS9 | 0.782913 | 3 | 0 | 3 |
| CYHR1 | SZT2 | 0.782381 | 3 | 0 | 3 |
| CYHR1 | LSM14A | 0.77611 | 3 | 0 | 3 |
| CYHR1 | REC8 | 0.774491 | 3 | 0 | 3 |
| CYHR1 | NR1H3 | 0.773202 | 3 | 0 | 3 |
| CYHR1 | TMTC4 | 0.771521 | 3 | 0 | 3 |
| CYHR1 | KCTD15 | 0.770421 | 3 | 0 | 3 |
| CYHR1 | KRTCAP2 | 0.765352 | 3 | 0 | 3 |
| CYHR1 | APOL2 | 0.761639 | 3 | 0 | 3 |
| CYHR1 | GOSR1 | 0.758197 | 3 | 0 | 3 |
| CYHR1 | PTPRU | 0.75666 | 3 | 0 | 3 |
| CYHR1 | GPATCH1 | 0.749814 | 3 | 0 | 3 |
| CYHR1 | PPRC1 | 0.745137 | 3 | 0 | 3 |
| CYHR1 | ZNF683 | 0.737876 | 3 | 0 | 3 |
| CYHR1 | MR1 | 0.731859 | 3 | 0 | 3 |
| CYHR1 | MUS81 | 0.731485 | 3 | 0 | 3 |
For details and further investigation, click here
