| Full name: 5'-nucleotidase domain containing 3 | Alias Symbol: TU12B1-TY|FLJ11266 | ||
| Type: protein-coding gene | Cytoband: 12q23.3 | ||
| Entrez ID: 51559 | HGNC ID: HGNC:30826 | Ensembl Gene: ENSG00000111696 | OMIM ID: 611076 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of NT5DC3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NT5DC3 | 51559 | 218786_at | -1.0741 | 0.3900 | |
| GSE20347 | NT5DC3 | 51559 | 218786_at | 0.4632 | 0.0014 | |
| GSE23400 | NT5DC3 | 51559 | 218786_at | -0.0960 | 0.2021 | |
| GSE26886 | NT5DC3 | 51559 | 218786_at | 0.8713 | 0.0000 | |
| GSE29001 | NT5DC3 | 51559 | 218786_at | 0.3657 | 0.0625 | |
| GSE38129 | NT5DC3 | 51559 | 218786_at | 0.1799 | 0.3056 | |
| GSE45670 | NT5DC3 | 51559 | 218786_at | -0.3653 | 0.0653 | |
| GSE53622 | NT5DC3 | 51559 | 8178 | -0.1001 | 0.5718 | |
| GSE53624 | NT5DC3 | 51559 | 68669 | 0.0467 | 0.6314 | |
| GSE63941 | NT5DC3 | 51559 | 218786_at | -0.1161 | 0.6548 | |
| GSE77861 | NT5DC3 | 51559 | 218786_at | 0.2754 | 0.1409 | |
| GSE97050 | NT5DC3 | 51559 | A_32_P76720 | -0.6458 | 0.3058 | |
| SRP007169 | NT5DC3 | 51559 | RNAseq | 2.0725 | 0.0001 | |
| SRP008496 | NT5DC3 | 51559 | RNAseq | 2.3188 | 0.0000 | |
| SRP064894 | NT5DC3 | 51559 | RNAseq | -0.2521 | 0.4475 | |
| SRP133303 | NT5DC3 | 51559 | RNAseq | 0.0698 | 0.8705 | |
| SRP159526 | NT5DC3 | 51559 | RNAseq | -0.4430 | 0.3137 | |
| SRP193095 | NT5DC3 | 51559 | RNAseq | 0.9405 | 0.0000 | |
| SRP219564 | NT5DC3 | 51559 | RNAseq | -0.5382 | 0.5391 | |
| TCGA | NT5DC3 | 51559 | RNAseq | -0.2476 | 0.0238 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by NT5DC3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NT5DC3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NT5DC3 | 51559 | 3 | 2 | 25 | |
| GSE20123 | NT5DC3 | 51559 | 3 | 2 | 25 | |
| GSE43470 | NT5DC3 | 51559 | 2 | 0 | 41 | |
| GSE46452 | NT5DC3 | 51559 | 9 | 1 | 49 | |
| GSE47630 | NT5DC3 | 51559 | 9 | 1 | 30 | |
| GSE54993 | NT5DC3 | 51559 | 0 | 5 | 65 | |
| GSE54994 | NT5DC3 | 51559 | 4 | 2 | 47 | |
| GSE60625 | NT5DC3 | 51559 | 0 | 0 | 11 | |
| GSE74703 | NT5DC3 | 51559 | 2 | 0 | 34 | |
| GSE74704 | NT5DC3 | 51559 | 1 | 2 | 17 | |
| TCGA | NT5DC3 | 51559 | 19 | 10 | 67 |
Total number of gains: 52; Total number of losses: 25; Total Number of normals: 411.
Somatic mutations of NT5DC3:
Generating mutation plots.
Highly correlated genes for NT5DC3:
Showing top 20/410 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NT5DC3 | NPY | 0.736681 | 5 | 0 | 5 |
| NT5DC3 | DOCK11 | 0.735273 | 3 | 0 | 3 |
| NT5DC3 | MTERF3 | 0.729248 | 3 | 0 | 3 |
| NT5DC3 | C9orf24 | 0.729152 | 4 | 0 | 3 |
| NT5DC3 | TCEAL3 | 0.715053 | 3 | 0 | 3 |
| NT5DC3 | IGF1R | 0.708986 | 3 | 0 | 3 |
| NT5DC3 | DMGDH | 0.696747 | 3 | 0 | 3 |
| NT5DC3 | DLGAP1-AS1 | 0.696125 | 3 | 0 | 3 |
| NT5DC3 | PPP1R12C | 0.692352 | 5 | 0 | 4 |
| NT5DC3 | SMPX | 0.679342 | 6 | 0 | 5 |
| NT5DC3 | ZNF575 | 0.674034 | 3 | 0 | 3 |
| NT5DC3 | SMYD4 | 0.671782 | 3 | 0 | 3 |
| NT5DC3 | CDHR3 | 0.669314 | 4 | 0 | 3 |
| NT5DC3 | LIFR | 0.669117 | 3 | 0 | 3 |
| NT5DC3 | CCDC136 | 0.6684 | 4 | 0 | 3 |
| NT5DC3 | ADCY2 | 0.666573 | 4 | 0 | 4 |
| NT5DC3 | HECTD2 | 0.66627 | 4 | 0 | 3 |
| NT5DC3 | SSC5D | 0.663288 | 3 | 0 | 3 |
| NT5DC3 | PTBP2 | 0.661024 | 3 | 0 | 3 |
| NT5DC3 | ASAP1 | 0.660762 | 4 | 0 | 3 |
For details and further investigation, click here
