| Full name: SET and MYND domain containing 4 | Alias Symbol: KIAA1936|ZMYND21 | ||
| Type: protein-coding gene | Cytoband: 17p13.3 | ||
| Entrez ID: 114826 | HGNC ID: HGNC:21067 | Ensembl Gene: ENSG00000186532 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of SMYD4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SMYD4 | 114826 | 229175_at | 0.4063 | 0.1374 | |
| GSE26886 | SMYD4 | 114826 | 229175_at | 1.3974 | 0.0000 | |
| GSE45670 | SMYD4 | 114826 | 229175_at | 0.4765 | 0.0086 | |
| GSE53622 | SMYD4 | 114826 | 5240 | 0.5106 | 0.0000 | |
| GSE53624 | SMYD4 | 114826 | 5240 | 0.7661 | 0.0000 | |
| GSE63941 | SMYD4 | 114826 | 229175_at | 0.0928 | 0.8216 | |
| GSE77861 | SMYD4 | 114826 | 229175_at | 0.3768 | 0.0352 | |
| GSE97050 | SMYD4 | 114826 | A_24_P307175 | 0.0513 | 0.8657 | |
| SRP007169 | SMYD4 | 114826 | RNAseq | 1.3374 | 0.0008 | |
| SRP008496 | SMYD4 | 114826 | RNAseq | 1.1800 | 0.0001 | |
| SRP064894 | SMYD4 | 114826 | RNAseq | 0.7333 | 0.0000 | |
| SRP133303 | SMYD4 | 114826 | RNAseq | 0.1529 | 0.1487 | |
| SRP159526 | SMYD4 | 114826 | RNAseq | 0.7117 | 0.0001 | |
| SRP193095 | SMYD4 | 114826 | RNAseq | 0.6633 | 0.0000 | |
| SRP219564 | SMYD4 | 114826 | RNAseq | 0.6476 | 0.1264 | |
| TCGA | SMYD4 | 114826 | RNAseq | 0.0449 | 0.4469 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by SMYD4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SMYD4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SMYD4 | 114826 | 4 | 2 | 24 | |
| GSE20123 | SMYD4 | 114826 | 4 | 3 | 23 | |
| GSE43470 | SMYD4 | 114826 | 3 | 6 | 34 | |
| GSE46452 | SMYD4 | 114826 | 34 | 1 | 24 | |
| GSE47630 | SMYD4 | 114826 | 8 | 1 | 31 | |
| GSE54993 | SMYD4 | 114826 | 9 | 3 | 58 | |
| GSE54994 | SMYD4 | 114826 | 8 | 8 | 37 | |
| GSE60625 | SMYD4 | 114826 | 4 | 0 | 7 | |
| GSE74703 | SMYD4 | 114826 | 2 | 3 | 31 | |
| GSE74704 | SMYD4 | 114826 | 2 | 1 | 17 | |
| TCGA | SMYD4 | 114826 | 20 | 21 | 55 |
Total number of gains: 98; Total number of losses: 49; Total Number of normals: 341.
Somatic mutations of SMYD4:
Generating mutation plots.
Highly correlated genes for SMYD4:
Showing top 20/391 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SMYD4 | MAFK | 0.755126 | 3 | 0 | 3 |
| SMYD4 | MTERF3 | 0.715759 | 4 | 0 | 4 |
| SMYD4 | HOXC9 | 0.70516 | 5 | 0 | 5 |
| SMYD4 | NEB | 0.699353 | 4 | 0 | 4 |
| SMYD4 | RASL11B | 0.686838 | 3 | 0 | 3 |
| SMYD4 | BMP8B | 0.677202 | 4 | 0 | 4 |
| SMYD4 | TAF5L | 0.676924 | 5 | 0 | 4 |
| SMYD4 | NT5DC3 | 0.671782 | 3 | 0 | 3 |
| SMYD4 | MLF1 | 0.670934 | 7 | 0 | 6 |
| SMYD4 | POFUT2 | 0.668304 | 4 | 0 | 4 |
| SMYD4 | ANKRD53 | 0.665823 | 3 | 0 | 3 |
| SMYD4 | EIF5A2 | 0.665108 | 6 | 0 | 4 |
| SMYD4 | COLGALT1 | 0.664257 | 6 | 0 | 6 |
| SMYD4 | CDCA7L | 0.660952 | 7 | 0 | 6 |
| SMYD4 | DVL2 | 0.660839 | 5 | 0 | 4 |
| SMYD4 | SCN9A | 0.656971 | 3 | 0 | 3 |
| SMYD4 | SLC52A1 | 0.656734 | 4 | 0 | 4 |
| SMYD4 | VAMP4 | 0.655807 | 3 | 0 | 3 |
| SMYD4 | HOXB7 | 0.655456 | 6 | 0 | 6 |
| SMYD4 | BLACAT1 | 0.653705 | 3 | 0 | 3 |
For details and further investigation, click here
