C9orf24

 

Full name: chromosome 9 open reading frame 24 Alias Symbol: bA573M23.4|NYD-SP22|MGC32921|MGC33614|CBE1|SMRP1
Type: protein-coding gene Cytoband: 9p13.3
Entrez ID: 84688 HGNC ID: HGNC:19919 Ensembl Gene: ENSG00000164972 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of C9orf24:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 C9orf24 84688 229012_at -0.6531 0.4630
GSE26886 C9orf24 84688 229012_at 0.2243 0.1201
GSE45670 C9orf24 84688 229012_at -0.1658 0.3907
GSE53622 C9orf24 84688 44059 0.0210 0.7907
GSE53624 C9orf24 84688 44059 -0.1117 0.0748
GSE63941 C9orf24 84688 229012_at -0.0537 0.8595
GSE77861 C9orf24 84688 229012_at -0.0841 0.5089
GSE97050 C9orf24 84688 A_23_P217009 -0.4304 0.2736
SRP159526 C9orf24 84688 RNAseq 0.2165 0.7348
TCGA C9orf24 84688 RNAseq -1.2553 0.0079

Upregulated datasets: 0; Downregulated datasets: 1.  


 

Survival by C9orf24 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of C9orf24:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 C9orf24 84688 4 13 13
GSE20123 C9orf24 84688 4 13 13
GSE43470 C9orf24 84688 3 10 30
GSE46452 C9orf24 84688 6 15 38
GSE47630 C9orf24 84688 1 20 19
GSE54993 C9orf24 84688 6 0 64
GSE54994 C9orf24 84688 6 12 35
GSE60625 C9orf24 84688 0 0 11
GSE74703 C9orf24 84688 2 7 27
GSE74704 C9orf24 84688 0 11 9
TCGA C9orf24 84688 17 44 35

Total number of gains: 49; Total number of losses: 145; Total Number of normals: 294.  


 

Somatic mutations of C9orf24:

 

Generating mutation plots.

 

Highly correlated genes for C9orf24:

 

Showing top 20/111 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
C9orf24NPY0.795775303
C9orf24GRIK30.774912303
C9orf24CACNA1H0.747733303
C9orf24NT5DC30.729152403
C9orf24SMPX0.716481403
C9orf24CNGA40.70725303
C9orf24OSR10.703957303
C9orf24FAT40.701323303
C9orf24RYR20.69526303
C9orf24SAMD4A0.69473403
C9orf24DGKG0.688924303
C9orf24FRMD10.681031303
C9orf24KCNF10.680106504
C9orf24RELN0.679613303
C9orf24COL4A60.67944303
C9orf24OR3A30.679183303
C9orf24HECTD20.677104303
C9orf24RNF2160.675995404
C9orf24LMO30.673399303
C9orf24MOB20.670185403

For details and further investigation, click here