| Full name: coiled-coil domain containing 136 | Alias Symbol: KIAA1793|NAG6|DKFZP434G156 | ||
| Type: protein-coding gene | Cytoband: 7q32.1 | ||
| Entrez ID: 64753 | HGNC ID: HGNC:22225 | Ensembl Gene: ENSG00000128596 | OMIM ID: 611902 |
| Drug and gene relationship at DGIdb | |||
Expression of CCDC136:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCDC136 | 64753 | 226972_s_at | -0.5319 | 0.5087 | |
| GSE26886 | CCDC136 | 64753 | 226972_s_at | 0.4290 | 0.0123 | |
| GSE45670 | CCDC136 | 64753 | 226972_s_at | -0.1904 | 0.4347 | |
| GSE53622 | CCDC136 | 64753 | 48782 | -0.2039 | 0.1774 | |
| GSE53624 | CCDC136 | 64753 | 48782 | -0.2562 | 0.0166 | |
| GSE63941 | CCDC136 | 64753 | 226972_s_at | -1.2069 | 0.0192 | |
| GSE77861 | CCDC136 | 64753 | 226972_s_at | 0.0448 | 0.7264 | |
| GSE97050 | CCDC136 | 64753 | A_33_P3287825 | -0.4111 | 0.3961 | |
| SRP064894 | CCDC136 | 64753 | RNAseq | 0.4913 | 0.1265 | |
| SRP133303 | CCDC136 | 64753 | RNAseq | 0.0703 | 0.8752 | |
| SRP159526 | CCDC136 | 64753 | RNAseq | 0.6095 | 0.1530 | |
| SRP219564 | CCDC136 | 64753 | RNAseq | -0.7445 | 0.3788 | |
| TCGA | CCDC136 | 64753 | RNAseq | -0.4429 | 0.0798 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by CCDC136 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CCDC136:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCDC136 | 64753 | 8 | 1 | 21 | |
| GSE20123 | CCDC136 | 64753 | 8 | 1 | 21 | |
| GSE43470 | CCDC136 | 64753 | 2 | 3 | 38 | |
| GSE46452 | CCDC136 | 64753 | 7 | 2 | 50 | |
| GSE47630 | CCDC136 | 64753 | 7 | 4 | 29 | |
| GSE54993 | CCDC136 | 64753 | 3 | 5 | 62 | |
| GSE54994 | CCDC136 | 64753 | 8 | 7 | 38 | |
| GSE60625 | CCDC136 | 64753 | 0 | 0 | 11 | |
| GSE74703 | CCDC136 | 64753 | 2 | 3 | 31 | |
| GSE74704 | CCDC136 | 64753 | 4 | 1 | 15 | |
| TCGA | CCDC136 | 64753 | 28 | 22 | 46 |
Total number of gains: 77; Total number of losses: 49; Total Number of normals: 362.
Somatic mutations of CCDC136:
Generating mutation plots.
Highly correlated genes for CCDC136:
Showing top 20/686 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCDC136 | ST6GAL2 | 0.807383 | 3 | 0 | 3 |
| CCDC136 | MITF | 0.790431 | 3 | 0 | 3 |
| CCDC136 | LMO3 | 0.787655 | 4 | 0 | 4 |
| CCDC136 | FLNA | 0.787351 | 3 | 0 | 3 |
| CCDC136 | SYNC | 0.782357 | 3 | 0 | 3 |
| CCDC136 | MYOT | 0.775165 | 3 | 0 | 3 |
| CCDC136 | TLN1 | 0.761224 | 3 | 0 | 3 |
| CCDC136 | YPEL1 | 0.760498 | 4 | 0 | 4 |
| CCDC136 | ATP2B4 | 0.755177 | 3 | 0 | 3 |
| CCDC136 | TPPP | 0.749032 | 3 | 0 | 3 |
| CCDC136 | ALDH1A2 | 0.748057 | 3 | 0 | 3 |
| CCDC136 | MYOM2 | 0.744589 | 3 | 0 | 3 |
| CCDC136 | FIBIN | 0.744448 | 3 | 0 | 3 |
| CCDC136 | DCHS1 | 0.73718 | 5 | 0 | 5 |
| CCDC136 | THRA | 0.736298 | 4 | 0 | 3 |
| CCDC136 | AGBL3 | 0.734895 | 3 | 0 | 3 |
| CCDC136 | TNIK | 0.727082 | 3 | 0 | 3 |
| CCDC136 | CELF6 | 0.726029 | 3 | 0 | 3 |
| CCDC136 | PRKAG2 | 0.723518 | 3 | 0 | 3 |
| CCDC136 | MAOB | 0.722399 | 4 | 0 | 3 |
For details and further investigation, click here
