| Full name: 5',3'-nucleotidase, mitochondrial | Alias Symbol: dNT-2|dNT2|mdN | ||
| Type: protein-coding gene | Cytoband: 17p11.2 | ||
| Entrez ID: 56953 | HGNC ID: HGNC:15769 | Ensembl Gene: ENSG00000205309 | OMIM ID: 605292 |
| Drug and gene relationship at DGIdb | |||
Expression of NT5M:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NT5M | 56953 | 219708_at | -0.0297 | 0.9431 | |
| GSE20347 | NT5M | 56953 | 219708_at | -0.1116 | 0.3546 | |
| GSE23400 | NT5M | 56953 | 219708_at | -0.2126 | 0.0000 | |
| GSE26886 | NT5M | 56953 | 219708_at | 0.5672 | 0.0000 | |
| GSE29001 | NT5M | 56953 | 219708_at | -0.1130 | 0.5521 | |
| GSE38129 | NT5M | 56953 | 219708_at | -0.0854 | 0.4454 | |
| GSE45670 | NT5M | 56953 | 219708_at | -0.0832 | 0.4537 | |
| GSE53622 | NT5M | 56953 | 77866 | 0.0686 | 0.5777 | |
| GSE53624 | NT5M | 56953 | 77866 | 0.5241 | 0.0001 | |
| GSE63941 | NT5M | 56953 | 219708_at | 0.6437 | 0.1298 | |
| GSE77861 | NT5M | 56953 | 219708_at | -0.0257 | 0.8819 | |
| GSE97050 | NT5M | 56953 | A_33_P3242863 | -0.1816 | 0.5493 | |
| SRP064894 | NT5M | 56953 | RNAseq | 1.3868 | 0.0023 | |
| SRP133303 | NT5M | 56953 | RNAseq | -0.0232 | 0.9566 | |
| SRP159526 | NT5M | 56953 | RNAseq | 1.2793 | 0.0261 | |
| SRP219564 | NT5M | 56953 | RNAseq | 0.8215 | 0.3295 | |
| TCGA | NT5M | 56953 | RNAseq | 0.3957 | 0.1211 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by NT5M expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NT5M:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NT5M | 56953 | 3 | 3 | 24 | |
| GSE20123 | NT5M | 56953 | 3 | 4 | 23 | |
| GSE43470 | NT5M | 56953 | 1 | 5 | 37 | |
| GSE46452 | NT5M | 56953 | 34 | 1 | 24 | |
| GSE47630 | NT5M | 56953 | 7 | 1 | 32 | |
| GSE54993 | NT5M | 56953 | 3 | 3 | 64 | |
| GSE54994 | NT5M | 56953 | 6 | 5 | 42 | |
| GSE60625 | NT5M | 56953 | 4 | 0 | 7 | |
| GSE74703 | NT5M | 56953 | 1 | 2 | 33 | |
| GSE74704 | NT5M | 56953 | 2 | 1 | 17 | |
| TCGA | NT5M | 56953 | 18 | 23 | 55 |
Total number of gains: 82; Total number of losses: 48; Total Number of normals: 358.
Somatic mutations of NT5M:
Generating mutation plots.
Highly correlated genes for NT5M:
Showing top 20/396 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NT5M | RGS3 | 0.775312 | 3 | 0 | 3 |
| NT5M | ENO2 | 0.747585 | 4 | 0 | 4 |
| NT5M | CALML4 | 0.74248 | 3 | 0 | 3 |
| NT5M | EMD | 0.730504 | 4 | 0 | 4 |
| NT5M | TP53I13 | 0.729104 | 3 | 0 | 3 |
| NT5M | C11orf96 | 0.727807 | 3 | 0 | 3 |
| NT5M | C11orf49 | 0.724216 | 3 | 0 | 3 |
| NT5M | INO80E | 0.722015 | 3 | 0 | 3 |
| NT5M | HES4 | 0.715911 | 4 | 0 | 4 |
| NT5M | RAB37 | 0.713751 | 3 | 0 | 3 |
| NT5M | ADAMTS10 | 0.712406 | 4 | 0 | 4 |
| NT5M | SRRT | 0.703119 | 3 | 0 | 3 |
| NT5M | STRADA | 0.700649 | 3 | 0 | 3 |
| NT5M | MYH7 | 0.695083 | 3 | 0 | 3 |
| NT5M | PI16 | 0.69256 | 4 | 0 | 4 |
| NT5M | ABRA | 0.691948 | 4 | 0 | 4 |
| NT5M | MRPL33 | 0.69154 | 4 | 0 | 3 |
| NT5M | RILP | 0.687452 | 4 | 0 | 4 |
| NT5M | WIZ | 0.682983 | 3 | 0 | 3 |
| NT5M | XAB2 | 0.681976 | 3 | 0 | 3 |
For details and further investigation, click here
