| Full name: calmodulin like 4 | Alias Symbol: MGC4809|NY-BR-20 | ||
| Type: protein-coding gene | Cytoband: 15q23 | ||
| Entrez ID: 91860 | HGNC ID: HGNC:18445 | Ensembl Gene: ENSG00000129007 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
CALML4 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04024 | cAMP signaling pathway |
Expression of CALML4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CALML4 | 91860 | 221879_at | 0.4035 | 0.5869 | |
| GSE20347 | CALML4 | 91860 | 221879_at | 0.7924 | 0.0062 | |
| GSE23400 | CALML4 | 91860 | 221879_at | 0.0836 | 0.3180 | |
| GSE26886 | CALML4 | 91860 | 221879_at | 1.2057 | 0.0000 | |
| GSE29001 | CALML4 | 91860 | 221879_at | 0.5466 | 0.0553 | |
| GSE38129 | CALML4 | 91860 | 221879_at | 0.3212 | 0.3536 | |
| GSE45670 | CALML4 | 91860 | 221879_at | 0.3703 | 0.0569 | |
| GSE63941 | CALML4 | 91860 | 221879_at | 1.7309 | 0.0139 | |
| GSE77861 | CALML4 | 91860 | 64408_s_at | 0.4493 | 0.0363 | |
| GSE97050 | CALML4 | 91860 | A_23_P129188 | -0.5168 | 0.3964 | |
| SRP007169 | CALML4 | 91860 | RNAseq | 0.5799 | 0.3452 | |
| SRP064894 | CALML4 | 91860 | RNAseq | 0.2916 | 0.1092 | |
| SRP133303 | CALML4 | 91860 | RNAseq | 0.1843 | 0.4450 | |
| SRP159526 | CALML4 | 91860 | RNAseq | 0.5370 | 0.0894 | |
| SRP193095 | CALML4 | 91860 | RNAseq | 0.1580 | 0.5115 | |
| SRP219564 | CALML4 | 91860 | RNAseq | 0.0925 | 0.8765 | |
| TCGA | CALML4 | 91860 | RNAseq | -0.2319 | 0.0002 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by CALML4 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of CALML4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CALML4 | 91860 | 7 | 1 | 22 | |
| GSE20123 | CALML4 | 91860 | 7 | 1 | 22 | |
| GSE43470 | CALML4 | 91860 | 4 | 6 | 33 | |
| GSE46452 | CALML4 | 91860 | 3 | 7 | 49 | |
| GSE47630 | CALML4 | 91860 | 8 | 10 | 22 | |
| GSE54993 | CALML4 | 91860 | 5 | 6 | 59 | |
| GSE54994 | CALML4 | 91860 | 5 | 7 | 41 | |
| GSE60625 | CALML4 | 91860 | 4 | 0 | 7 | |
| GSE74703 | CALML4 | 91860 | 4 | 3 | 29 | |
| GSE74704 | CALML4 | 91860 | 3 | 1 | 16 | |
| TCGA | CALML4 | 91860 | 10 | 15 | 71 |
Total number of gains: 60; Total number of losses: 57; Total Number of normals: 371.
Somatic mutations of CALML4:
Generating mutation plots.
Highly correlated genes for CALML4:
Showing top 20/706 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CALML4 | SOX13 | 0.77246 | 3 | 0 | 3 |
| CALML4 | ATXN2 | 0.749312 | 3 | 0 | 3 |
| CALML4 | NT5M | 0.74248 | 3 | 0 | 3 |
| CALML4 | LSM10 | 0.733471 | 3 | 0 | 3 |
| CALML4 | PLEKHA3 | 0.733444 | 4 | 0 | 4 |
| CALML4 | IL3RA | 0.730563 | 3 | 0 | 3 |
| CALML4 | RPS19BP1 | 0.716625 | 3 | 0 | 3 |
| CALML4 | MARVELD1 | 0.706697 | 3 | 0 | 3 |
| CALML4 | NDUFV1 | 0.706614 | 3 | 0 | 3 |
| CALML4 | POLR2J | 0.703467 | 4 | 0 | 4 |
| CALML4 | C15orf61 | 0.696465 | 4 | 0 | 3 |
| CALML4 | INPP4A | 0.694677 | 4 | 0 | 3 |
| CALML4 | NR2C2AP | 0.692654 | 3 | 0 | 3 |
| CALML4 | TPBG | 0.692066 | 5 | 0 | 5 |
| CALML4 | COL4A5 | 0.690436 | 6 | 0 | 6 |
| CALML4 | CLU | 0.68806 | 3 | 0 | 3 |
| CALML4 | NENF | 0.686196 | 5 | 0 | 5 |
| CALML4 | CYSTM1 | 0.685418 | 3 | 0 | 3 |
| CALML4 | FIBP | 0.684384 | 3 | 0 | 3 |
| CALML4 | GAS2L1 | 0.684234 | 3 | 0 | 3 |
For details and further investigation, click here
