| Full name: nudix hydrolase 6 | Alias Symbol: gfg-1|gfg|FGF2AS|FGF-AS | ||
| Type: protein-coding gene | Cytoband: 4q28.1 | ||
| Entrez ID: 11162 | HGNC ID: HGNC:8053 | Ensembl Gene: ENSG00000170917 | OMIM ID: 606261 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of NUDT6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NUDT6 | 11162 | 230329_s_at | 0.0006 | 0.9994 | |
| GSE20347 | NUDT6 | 11162 | 220183_s_at | -0.1263 | 0.2361 | |
| GSE23400 | NUDT6 | 11162 | 220183_s_at | -0.0755 | 0.0001 | |
| GSE26886 | NUDT6 | 11162 | 230329_s_at | 0.1920 | 0.4286 | |
| GSE29001 | NUDT6 | 11162 | 220183_s_at | -0.0336 | 0.8851 | |
| GSE38129 | NUDT6 | 11162 | 220183_s_at | -0.0960 | 0.6081 | |
| GSE45670 | NUDT6 | 11162 | 230329_s_at | -0.4794 | 0.0155 | |
| GSE63941 | NUDT6 | 11162 | 230329_s_at | 0.2229 | 0.7391 | |
| GSE77861 | NUDT6 | 11162 | 230329_s_at | -0.1284 | 0.3569 | |
| GSE97050 | NUDT6 | 11162 | A_23_P155857 | -0.2168 | 0.4808 | |
| SRP064894 | NUDT6 | 11162 | RNAseq | 0.1931 | 0.4690 | |
| SRP133303 | NUDT6 | 11162 | RNAseq | -0.4647 | 0.0774 | |
| SRP159526 | NUDT6 | 11162 | RNAseq | -0.2294 | 0.5191 | |
| SRP193095 | NUDT6 | 11162 | RNAseq | -0.2031 | 0.2464 | |
| SRP219564 | NUDT6 | 11162 | RNAseq | -0.0142 | 0.9749 | |
| TCGA | NUDT6 | 11162 | RNAseq | -0.1540 | 0.2535 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NUDT6 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of NUDT6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NUDT6 | 11162 | 0 | 13 | 17 | |
| GSE20123 | NUDT6 | 11162 | 0 | 13 | 17 | |
| GSE43470 | NUDT6 | 11162 | 0 | 13 | 30 | |
| GSE46452 | NUDT6 | 11162 | 1 | 36 | 22 | |
| GSE47630 | NUDT6 | 11162 | 0 | 22 | 18 | |
| GSE54993 | NUDT6 | 11162 | 9 | 0 | 61 | |
| GSE54994 | NUDT6 | 11162 | 1 | 10 | 42 | |
| GSE60625 | NUDT6 | 11162 | 0 | 1 | 10 | |
| GSE74703 | NUDT6 | 11162 | 0 | 11 | 25 | |
| GSE74704 | NUDT6 | 11162 | 0 | 7 | 13 | |
| TCGA | NUDT6 | 11162 | 8 | 35 | 53 |
Total number of gains: 19; Total number of losses: 161; Total Number of normals: 308.
Somatic mutations of NUDT6:
Generating mutation plots.
Highly correlated genes for NUDT6:
Showing top 20/100 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NUDT6 | FGL2 | 0.669254 | 4 | 0 | 4 |
| NUDT6 | RASSF2 | 0.660677 | 3 | 0 | 3 |
| NUDT6 | ARHGAP6 | 0.658838 | 4 | 0 | 4 |
| NUDT6 | MAN1C1 | 0.656182 | 3 | 0 | 3 |
| NUDT6 | CPQ | 0.649264 | 3 | 0 | 3 |
| NUDT6 | MAGEH1 | 0.646648 | 3 | 0 | 3 |
| NUDT6 | FBXL7 | 0.643437 | 3 | 0 | 3 |
| NUDT6 | BEND5 | 0.639374 | 3 | 0 | 3 |
| NUDT6 | RPS27A | 0.637321 | 3 | 0 | 3 |
| NUDT6 | PDE1A | 0.63673 | 3 | 0 | 3 |
| NUDT6 | NLGN1 | 0.635929 | 3 | 0 | 3 |
| NUDT6 | TNS1 | 0.63366 | 3 | 0 | 3 |
| NUDT6 | ANK2 | 0.63205 | 3 | 0 | 3 |
| NUDT6 | CHRDL1 | 0.621829 | 3 | 0 | 3 |
| NUDT6 | SLC16A4 | 0.618675 | 3 | 0 | 3 |
| NUDT6 | ST6GALNAC3 | 0.616788 | 3 | 0 | 3 |
| NUDT6 | CTSF | 0.61593 | 3 | 0 | 3 |
| NUDT6 | STS | 0.611071 | 4 | 0 | 4 |
| NUDT6 | ARMCX1 | 0.610097 | 3 | 0 | 3 |
| NUDT6 | RCAN2 | 0.609579 | 3 | 0 | 3 |
For details and further investigation, click here
