| Full name: cathepsin F | Alias Symbol: CATSF|CLN13 | ||
| Type: protein-coding gene | Cytoband: 11q13.2 | ||
| Entrez ID: 8722 | HGNC ID: HGNC:2531 | Ensembl Gene: ENSG00000174080 | OMIM ID: 603539 |
| Drug and gene relationship at DGIdb | |||
CTSF involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04210 | Apoptosis |
Expression of CTSF:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CTSF | 8722 | 203657_s_at | -0.2842 | 0.7056 | |
| GSE20347 | CTSF | 8722 | 203657_s_at | 0.1270 | 0.3825 | |
| GSE23400 | CTSF | 8722 | 203657_s_at | -0.1312 | 0.0704 | |
| GSE26886 | CTSF | 8722 | 203657_s_at | 0.6511 | 0.0054 | |
| GSE29001 | CTSF | 8722 | 203657_s_at | 0.2954 | 0.4637 | |
| GSE38129 | CTSF | 8722 | 203657_s_at | -0.2019 | 0.4372 | |
| GSE45670 | CTSF | 8722 | 203657_s_at | -0.3564 | 0.0624 | |
| GSE53622 | CTSF | 8722 | 86665 | -0.3725 | 0.0151 | |
| GSE53624 | CTSF | 8722 | 86665 | 0.2026 | 0.1219 | |
| GSE63941 | CTSF | 8722 | 203657_s_at | -1.6003 | 0.0060 | |
| GSE77861 | CTSF | 8722 | 203657_s_at | -0.0138 | 0.9337 | |
| GSE97050 | CTSF | 8722 | A_23_P24433 | -0.4143 | 0.2813 | |
| SRP007169 | CTSF | 8722 | RNAseq | 0.4286 | 0.4309 | |
| SRP008496 | CTSF | 8722 | RNAseq | 1.3322 | 0.0031 | |
| SRP064894 | CTSF | 8722 | RNAseq | 0.3487 | 0.3955 | |
| SRP133303 | CTSF | 8722 | RNAseq | -0.0366 | 0.9100 | |
| SRP159526 | CTSF | 8722 | RNAseq | 0.5401 | 0.1132 | |
| SRP193095 | CTSF | 8722 | RNAseq | 0.6140 | 0.0030 | |
| SRP219564 | CTSF | 8722 | RNAseq | -0.3387 | 0.6619 | |
| TCGA | CTSF | 8722 | RNAseq | -0.4925 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by CTSF expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CTSF:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CTSF | 8722 | 9 | 4 | 17 | |
| GSE20123 | CTSF | 8722 | 9 | 4 | 17 | |
| GSE43470 | CTSF | 8722 | 6 | 1 | 36 | |
| GSE46452 | CTSF | 8722 | 12 | 3 | 44 | |
| GSE47630 | CTSF | 8722 | 9 | 4 | 27 | |
| GSE54993 | CTSF | 8722 | 3 | 0 | 67 | |
| GSE54994 | CTSF | 8722 | 9 | 5 | 39 | |
| GSE60625 | CTSF | 8722 | 0 | 3 | 8 | |
| GSE74703 | CTSF | 8722 | 4 | 0 | 32 | |
| GSE74704 | CTSF | 8722 | 7 | 2 | 11 | |
| TCGA | CTSF | 8722 | 27 | 6 | 63 |
Total number of gains: 95; Total number of losses: 32; Total Number of normals: 361.
Somatic mutations of CTSF:
Generating mutation plots.
Highly correlated genes for CTSF:
Showing top 20/1100 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CTSF | FIBIN | 0.769397 | 4 | 0 | 4 |
| CTSF | CD99L2 | 0.756461 | 5 | 0 | 5 |
| CTSF | STAG2 | 0.750293 | 3 | 0 | 3 |
| CTSF | ZSCAN21 | 0.746583 | 3 | 0 | 3 |
| CTSF | HERC2 | 0.746221 | 3 | 0 | 3 |
| CTSF | FXYD6 | 0.7403 | 9 | 0 | 8 |
| CTSF | ZNF512 | 0.736288 | 4 | 0 | 4 |
| CTSF | FEZ2 | 0.736202 | 3 | 0 | 3 |
| CTSF | LONRF2 | 0.720457 | 3 | 0 | 3 |
| CTSF | FNIP2 | 0.7194 | 4 | 0 | 4 |
| CTSF | RCN2 | 0.718856 | 3 | 0 | 3 |
| CTSF | DIXDC1 | 0.710523 | 8 | 0 | 8 |
| CTSF | NBR1 | 0.710265 | 4 | 0 | 4 |
| CTSF | NDUFB2 | 0.705254 | 4 | 0 | 4 |
| CTSF | TNFSF12 | 0.704913 | 4 | 0 | 4 |
| CTSF | CCDC136 | 0.704062 | 4 | 0 | 4 |
| CTSF | ANXA6 | 0.701255 | 9 | 0 | 8 |
| CTSF | GRAMD1A | 0.700005 | 3 | 0 | 3 |
| CTSF | TSPAN18 | 0.698729 | 4 | 0 | 3 |
| CTSF | TLN1 | 0.698684 | 5 | 0 | 5 |
For details and further investigation, click here
