| Full name: ribosomal protein S27a | Alias Symbol: UBCEP80|Uba80|S27A | ||
| Type: protein-coding gene | Cytoband: 2p16.1 | ||
| Entrez ID: 6233 | HGNC ID: HGNC:10417 | Ensembl Gene: ENSG00000143947 | OMIM ID: 191343 |
| Drug and gene relationship at DGIdb | |||
Expression of RPS27A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RPS27A | 6233 | 200017_at | -0.0079 | 0.9764 | |
| GSE20347 | RPS27A | 6233 | 200017_at | 0.0713 | 0.5283 | |
| GSE23400 | RPS27A | 6233 | 200017_at | 0.0380 | 0.5256 | |
| GSE26886 | RPS27A | 6233 | 200017_at | 0.5026 | 0.0012 | |
| GSE29001 | RPS27A | 6233 | 200017_at | -0.0992 | 0.7337 | |
| GSE38129 | RPS27A | 6233 | 200017_at | 0.0538 | 0.4948 | |
| GSE45670 | RPS27A | 6233 | 200017_at | -0.0923 | 0.2123 | |
| GSE53622 | RPS27A | 6233 | 3173 | -0.5530 | 0.0000 | |
| GSE53624 | RPS27A | 6233 | 43973 | 0.0266 | 0.7704 | |
| GSE63941 | RPS27A | 6233 | 200017_at | 0.4224 | 0.0008 | |
| GSE77861 | RPS27A | 6233 | 200017_at | -0.0653 | 0.6395 | |
| GSE97050 | RPS27A | 6233 | A_32_P24581 | -0.0065 | 0.9866 | |
| SRP007169 | RPS27A | 6233 | RNAseq | 0.4023 | 0.3067 | |
| SRP008496 | RPS27A | 6233 | RNAseq | 0.4484 | 0.1263 | |
| SRP064894 | RPS27A | 6233 | RNAseq | -0.2537 | 0.4059 | |
| SRP133303 | RPS27A | 6233 | RNAseq | -0.2929 | 0.0330 | |
| SRP159526 | RPS27A | 6233 | RNAseq | -0.1030 | 0.5680 | |
| SRP193095 | RPS27A | 6233 | RNAseq | -0.6573 | 0.0001 | |
| SRP219564 | RPS27A | 6233 | RNAseq | -0.2873 | 0.2425 | |
| TCGA | RPS27A | 6233 | RNAseq | 0.0211 | 0.7092 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RPS27A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RPS27A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RPS27A | 6233 | 10 | 0 | 20 | |
| GSE20123 | RPS27A | 6233 | 9 | 0 | 21 | |
| GSE43470 | RPS27A | 6233 | 5 | 0 | 38 | |
| GSE46452 | RPS27A | 6233 | 2 | 3 | 54 | |
| GSE47630 | RPS27A | 6233 | 8 | 0 | 32 | |
| GSE54993 | RPS27A | 6233 | 0 | 5 | 65 | |
| GSE54994 | RPS27A | 6233 | 12 | 0 | 41 | |
| GSE60625 | RPS27A | 6233 | 0 | 3 | 8 | |
| GSE74703 | RPS27A | 6233 | 5 | 0 | 31 | |
| GSE74704 | RPS27A | 6233 | 9 | 0 | 11 | |
| TCGA | RPS27A | 6233 | 34 | 3 | 59 |
Total number of gains: 94; Total number of losses: 14; Total Number of normals: 380.
Somatic mutations of RPS27A:
Generating mutation plots.
Highly correlated genes for RPS27A:
Showing top 20/383 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RPS27A | C1orf56 | 0.817388 | 3 | 0 | 3 |
| RPS27A | TPD52 | 0.803018 | 3 | 0 | 3 |
| RPS27A | MRPS11 | 0.798531 | 3 | 0 | 3 |
| RPS27A | MARK1 | 0.760703 | 3 | 0 | 3 |
| RPS27A | RPS19BP1 | 0.758038 | 3 | 0 | 3 |
| RPS27A | TRAP1 | 0.75266 | 3 | 0 | 3 |
| RPS27A | SYNE2 | 0.724791 | 3 | 0 | 3 |
| RPS27A | CHCHD1 | 0.723335 | 3 | 0 | 3 |
| RPS27A | MCMBP | 0.719515 | 4 | 0 | 4 |
| RPS27A | ESCO1 | 0.717694 | 3 | 0 | 3 |
| RPS27A | PEX2 | 0.717056 | 3 | 0 | 3 |
| RPS27A | CHCHD6 | 0.714064 | 3 | 0 | 3 |
| RPS27A | RPAIN | 0.71245 | 3 | 0 | 3 |
| RPS27A | PLA2G12A | 0.701438 | 4 | 0 | 4 |
| RPS27A | MRPL46 | 0.694978 | 4 | 0 | 4 |
| RPS27A | SF3B6 | 0.692252 | 4 | 0 | 4 |
| RPS27A | GTF3C6 | 0.687675 | 3 | 0 | 3 |
| RPS27A | AURKAIP1 | 0.685114 | 3 | 0 | 3 |
| RPS27A | FBXO11 | 0.684368 | 4 | 0 | 3 |
| RPS27A | CTBP2 | 0.683633 | 3 | 0 | 3 |
For details and further investigation, click here
