| Full name: ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1p31.1 | ||
| Entrez ID: 256435 | HGNC ID: HGNC:19343 | Ensembl Gene: ENSG00000184005 | OMIM ID: 610133 |
| Drug and gene relationship at DGIdb | |||
Expression of ST6GALNAC3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ST6GALNAC3 | 256435 | 235334_at | -0.4892 | 0.4102 | |
| GSE26886 | ST6GALNAC3 | 256435 | 235334_at | -0.1276 | 0.2879 | |
| GSE45670 | ST6GALNAC3 | 256435 | 235334_at | -0.9163 | 0.0057 | |
| GSE53622 | ST6GALNAC3 | 256435 | 121393 | -0.7249 | 0.0000 | |
| GSE53624 | ST6GALNAC3 | 256435 | 17413 | -0.5146 | 0.0056 | |
| GSE63941 | ST6GALNAC3 | 256435 | 235334_at | -3.4291 | 0.0000 | |
| GSE77861 | ST6GALNAC3 | 256435 | 235334_at | -0.0697 | 0.6220 | |
| GSE97050 | ST6GALNAC3 | 256435 | A_33_P3275055 | -0.0432 | 0.8608 | |
| SRP064894 | ST6GALNAC3 | 256435 | RNAseq | 0.3206 | 0.4507 | |
| SRP133303 | ST6GALNAC3 | 256435 | RNAseq | -0.2167 | 0.2903 | |
| SRP159526 | ST6GALNAC3 | 256435 | RNAseq | 0.4577 | 0.2381 | |
| SRP193095 | ST6GALNAC3 | 256435 | RNAseq | -0.0660 | 0.7419 | |
| SRP219564 | ST6GALNAC3 | 256435 | RNAseq | 0.0818 | 0.8596 | |
| TCGA | ST6GALNAC3 | 256435 | RNAseq | -1.0481 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by ST6GALNAC3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ST6GALNAC3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ST6GALNAC3 | 256435 | 0 | 7 | 23 | |
| GSE20123 | ST6GALNAC3 | 256435 | 1 | 7 | 22 | |
| GSE43470 | ST6GALNAC3 | 256435 | 3 | 4 | 36 | |
| GSE46452 | ST6GALNAC3 | 256435 | 0 | 1 | 58 | |
| GSE47630 | ST6GALNAC3 | 256435 | 8 | 6 | 26 | |
| GSE54993 | ST6GALNAC3 | 256435 | 0 | 0 | 70 | |
| GSE54994 | ST6GALNAC3 | 256435 | 6 | 3 | 44 | |
| GSE60625 | ST6GALNAC3 | 256435 | 0 | 0 | 11 | |
| GSE74703 | ST6GALNAC3 | 256435 | 2 | 3 | 31 | |
| GSE74704 | ST6GALNAC3 | 256435 | 1 | 4 | 15 | |
| TCGA | ST6GALNAC3 | 256435 | 8 | 24 | 64 |
Total number of gains: 29; Total number of losses: 59; Total Number of normals: 400.
Somatic mutations of ST6GALNAC3:
Generating mutation plots.
Highly correlated genes for ST6GALNAC3:
Showing top 20/858 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ST6GALNAC3 | DCHS1 | 0.818909 | 4 | 0 | 4 |
| ST6GALNAC3 | RHOJ | 0.811618 | 4 | 0 | 4 |
| ST6GALNAC3 | SCUBE3 | 0.810389 | 3 | 0 | 3 |
| ST6GALNAC3 | SMPD1 | 0.794179 | 3 | 0 | 3 |
| ST6GALNAC3 | CNRIP1 | 0.784382 | 6 | 0 | 6 |
| ST6GALNAC3 | GRK5 | 0.773383 | 4 | 0 | 4 |
| ST6GALNAC3 | GNG11 | 0.765298 | 6 | 0 | 6 |
| ST6GALNAC3 | FZD4 | 0.762441 | 6 | 0 | 6 |
| ST6GALNAC3 | MAGI2-AS3 | 0.761888 | 6 | 0 | 6 |
| ST6GALNAC3 | TEK | 0.760031 | 6 | 0 | 6 |
| ST6GALNAC3 | ADAMTS5 | 0.753407 | 6 | 0 | 6 |
| ST6GALNAC3 | ANK2 | 0.74895 | 5 | 0 | 5 |
| ST6GALNAC3 | PDE1A | 0.748387 | 6 | 0 | 6 |
| ST6GALNAC3 | CCL8 | 0.745986 | 3 | 0 | 3 |
| ST6GALNAC3 | COL14A1 | 0.744987 | 6 | 0 | 6 |
| ST6GALNAC3 | ECSCR | 0.744016 | 6 | 0 | 6 |
| ST6GALNAC3 | C11orf96 | 0.738007 | 4 | 0 | 4 |
| ST6GALNAC3 | PCDH18 | 0.733443 | 6 | 0 | 6 |
| ST6GALNAC3 | JAM3 | 0.732477 | 6 | 0 | 6 |
| ST6GALNAC3 | FBN1 | 0.731071 | 4 | 0 | 4 |
For details and further investigation, click here
