| Full name: nucleoporin 214 | Alias Symbol: CAIN|CAN|D9S46E|N214 | ||
| Type: protein-coding gene | Cytoband: 9q34.13 | ||
| Entrez ID: 8021 | HGNC ID: HGNC:8064 | Ensembl Gene: ENSG00000126883 | OMIM ID: 114350 |
| Drug and gene relationship at DGIdb | |||
Expression of NUP214:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NUP214 | 8021 | 202155_s_at | 0.2360 | 0.6138 | |
| GSE20347 | NUP214 | 8021 | 202155_s_at | -0.1307 | 0.2843 | |
| GSE23400 | NUP214 | 8021 | 202155_s_at | -0.2361 | 0.0005 | |
| GSE26886 | NUP214 | 8021 | 202155_s_at | 0.4278 | 0.0145 | |
| GSE29001 | NUP214 | 8021 | 202155_s_at | -0.2377 | 0.2078 | |
| GSE38129 | NUP214 | 8021 | 202155_s_at | -0.0677 | 0.4976 | |
| GSE45670 | NUP214 | 8021 | 202155_s_at | -0.0191 | 0.9313 | |
| GSE53622 | NUP214 | 8021 | 51822 | -0.3851 | 0.0000 | |
| GSE53624 | NUP214 | 8021 | 51822 | -0.7790 | 0.0000 | |
| GSE63941 | NUP214 | 8021 | 202155_s_at | 0.2109 | 0.4317 | |
| GSE77861 | NUP214 | 8021 | 202155_s_at | 0.0525 | 0.6575 | |
| GSE97050 | NUP214 | 8021 | A_23_P257091 | -0.2558 | 0.4206 | |
| SRP007169 | NUP214 | 8021 | RNAseq | 0.0181 | 0.9666 | |
| SRP008496 | NUP214 | 8021 | RNAseq | -0.1165 | 0.6579 | |
| SRP064894 | NUP214 | 8021 | RNAseq | -0.8675 | 0.0002 | |
| SRP133303 | NUP214 | 8021 | RNAseq | -0.2179 | 0.2109 | |
| SRP159526 | NUP214 | 8021 | RNAseq | -0.1299 | 0.6685 | |
| SRP193095 | NUP214 | 8021 | RNAseq | -0.2642 | 0.0521 | |
| SRP219564 | NUP214 | 8021 | RNAseq | -0.4398 | 0.2400 | |
| TCGA | NUP214 | 8021 | RNAseq | 0.0164 | 0.7162 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NUP214 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NUP214:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NUP214 | 8021 | 6 | 9 | 15 | |
| GSE20123 | NUP214 | 8021 | 6 | 9 | 15 | |
| GSE43470 | NUP214 | 8021 | 5 | 7 | 31 | |
| GSE46452 | NUP214 | 8021 | 6 | 13 | 40 | |
| GSE47630 | NUP214 | 8021 | 3 | 16 | 21 | |
| GSE54993 | NUP214 | 8021 | 3 | 3 | 64 | |
| GSE54994 | NUP214 | 8021 | 12 | 9 | 32 | |
| GSE60625 | NUP214 | 8021 | 0 | 0 | 11 | |
| GSE74703 | NUP214 | 8021 | 5 | 5 | 26 | |
| GSE74704 | NUP214 | 8021 | 3 | 7 | 10 | |
| TCGA | NUP214 | 8021 | 27 | 26 | 43 |
Total number of gains: 76; Total number of losses: 104; Total Number of normals: 308.
Somatic mutations of NUP214:
Generating mutation plots.
Highly correlated genes for NUP214:
Showing top 20/66 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NUP214 | RNF222 | 0.734106 | 3 | 0 | 3 |
| NUP214 | ZBTB17 | 0.665873 | 3 | 0 | 3 |
| NUP214 | KMT2D | 0.651422 | 3 | 0 | 3 |
| NUP214 | RAD9A | 0.644565 | 4 | 0 | 4 |
| NUP214 | CTNND1 | 0.631497 | 3 | 0 | 3 |
| NUP214 | GLYCTK | 0.620295 | 3 | 0 | 3 |
| NUP214 | CRTC2 | 0.620043 | 3 | 0 | 3 |
| NUP214 | TIGD5 | 0.616822 | 5 | 0 | 4 |
| NUP214 | PHF12 | 0.604697 | 5 | 0 | 4 |
| NUP214 | ZMYND19 | 0.602854 | 4 | 0 | 3 |
| NUP214 | ATRNL1 | 0.600242 | 3 | 0 | 3 |
| NUP214 | TMPRSS11A | 0.588989 | 3 | 0 | 3 |
| NUP214 | DPH7 | 0.586634 | 5 | 0 | 3 |
| NUP214 | AP1G2 | 0.582222 | 4 | 0 | 3 |
| NUP214 | TRMT10B | 0.581899 | 3 | 0 | 3 |
| NUP214 | RANBP9 | 0.576419 | 6 | 0 | 4 |
| NUP214 | SFI1 | 0.574221 | 5 | 0 | 3 |
| NUP214 | PMPCA | 0.572801 | 4 | 0 | 3 |
| NUP214 | INPP5E | 0.571904 | 5 | 0 | 3 |
| NUP214 | PLD1 | 0.569779 | 4 | 0 | 3 |
For details and further investigation, click here
