| Full name: RAD9 checkpoint clamp component A | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 11q13.2 | ||
| Entrez ID: 5883 | HGNC ID: HGNC:9827 | Ensembl Gene: ENSG00000172613 | OMIM ID: 603761 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of RAD9A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RAD9A | 5883 | 204828_at | 0.5455 | 0.2216 | |
| GSE20347 | RAD9A | 5883 | 204828_at | 0.7705 | 0.0005 | |
| GSE23400 | RAD9A | 5883 | 204828_at | 0.2530 | 0.0000 | |
| GSE26886 | RAD9A | 5883 | 204828_at | 0.3911 | 0.0140 | |
| GSE29001 | RAD9A | 5883 | 204828_at | 0.4103 | 0.0992 | |
| GSE38129 | RAD9A | 5883 | 204828_at | 0.7104 | 0.0000 | |
| GSE45670 | RAD9A | 5883 | 204828_at | 0.5543 | 0.0031 | |
| GSE53622 | RAD9A | 5883 | 76617 | -2.0139 | 0.0000 | |
| GSE53624 | RAD9A | 5883 | 76617 | -2.0381 | 0.0000 | |
| GSE63941 | RAD9A | 5883 | 204828_at | 1.4758 | 0.0009 | |
| GSE77861 | RAD9A | 5883 | 204828_at | 0.4479 | 0.0420 | |
| GSE97050 | RAD9A | 5883 | A_24_P21715 | 0.2045 | 0.4201 | |
| SRP007169 | RAD9A | 5883 | RNAseq | -0.6816 | 0.2086 | |
| SRP064894 | RAD9A | 5883 | RNAseq | 0.3728 | 0.0303 | |
| SRP133303 | RAD9A | 5883 | RNAseq | 0.1575 | 0.4516 | |
| SRP193095 | RAD9A | 5883 | RNAseq | 0.3922 | 0.0052 | |
| SRP219564 | RAD9A | 5883 | RNAseq | 0.7319 | 0.1486 | |
| TCGA | RAD9A | 5883 | RNAseq | 0.3038 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 2.
Survival by RAD9A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RAD9A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RAD9A | 5883 | 9 | 4 | 17 | |
| GSE20123 | RAD9A | 5883 | 9 | 4 | 17 | |
| GSE43470 | RAD9A | 5883 | 6 | 1 | 36 | |
| GSE46452 | RAD9A | 5883 | 13 | 3 | 43 | |
| GSE47630 | RAD9A | 5883 | 8 | 5 | 27 | |
| GSE54993 | RAD9A | 5883 | 3 | 1 | 66 | |
| GSE54994 | RAD9A | 5883 | 13 | 4 | 36 | |
| GSE60625 | RAD9A | 5883 | 0 | 3 | 8 | |
| GSE74703 | RAD9A | 5883 | 4 | 0 | 32 | |
| GSE74704 | RAD9A | 5883 | 7 | 2 | 11 | |
| TCGA | RAD9A | 5883 | 29 | 8 | 59 |
Total number of gains: 101; Total number of losses: 35; Total Number of normals: 352.
Somatic mutations of RAD9A:
Generating mutation plots.
Highly correlated genes for RAD9A:
Showing top 20/257 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RAD9A | UPB1 | 0.714688 | 4 | 0 | 4 |
| RAD9A | FBRSL1 | 0.712617 | 4 | 0 | 3 |
| RAD9A | UPK3B | 0.696388 | 3 | 0 | 3 |
| RAD9A | MUC5AC | 0.693399 | 3 | 0 | 3 |
| RAD9A | TRMT10B | 0.686772 | 3 | 0 | 3 |
| RAD9A | C19orf57 | 0.682413 | 4 | 0 | 4 |
| RAD9A | KLRG2 | 0.675392 | 3 | 0 | 3 |
| RAD9A | ARHGAP40 | 0.6741 | 3 | 0 | 3 |
| RAD9A | BCL9L | 0.667668 | 3 | 0 | 3 |
| RAD9A | PLEKHH1 | 0.667002 | 3 | 0 | 3 |
| RAD9A | TMEM241 | 0.666709 | 3 | 0 | 3 |
| RAD9A | LTA4H | 0.665778 | 3 | 0 | 3 |
| RAD9A | ZC3H12D | 0.663595 | 4 | 0 | 3 |
| RAD9A | POLR1A | 0.652322 | 3 | 0 | 3 |
| RAD9A | PDP2 | 0.651868 | 3 | 0 | 3 |
| RAD9A | CDX1 | 0.651053 | 4 | 0 | 3 |
| RAD9A | ZBTB17 | 0.650734 | 8 | 0 | 6 |
| RAD9A | MOB3C | 0.650273 | 3 | 0 | 3 |
| RAD9A | KRTAP4-1 | 0.649807 | 5 | 0 | 4 |
| RAD9A | CRX | 0.64949 | 4 | 0 | 3 |
For details and further investigation, click here
