| Full name: SFI1 centrin binding protein | Alias Symbol: KIAA0542|PISD|PPP1R139 | ||
| Type: protein-coding gene | Cytoband: 22q12.2 | ||
| Entrez ID: 9814 | HGNC ID: HGNC:29064 | Ensembl Gene: ENSG00000198089 | OMIM ID: 612765 |
| Drug and gene relationship at DGIdb | |||
Expression of SFI1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SFI1 | 9814 | 213431_x_at | 0.1789 | 0.4303 | |
| GSE20347 | SFI1 | 9814 | 213431_x_at | 0.1073 | 0.3620 | |
| GSE23400 | SFI1 | 9814 | 215699_x_at | -0.0596 | 0.2474 | |
| GSE26886 | SFI1 | 9814 | 213431_x_at | 0.2820 | 0.0876 | |
| GSE29001 | SFI1 | 9814 | 215699_x_at | 0.1650 | 0.2212 | |
| GSE38129 | SFI1 | 9814 | 213431_x_at | 0.0444 | 0.6551 | |
| GSE45670 | SFI1 | 9814 | 213431_x_at | 0.1334 | 0.1721 | |
| GSE53622 | SFI1 | 9814 | 99839 | -2.0152 | 0.0000 | |
| GSE53624 | SFI1 | 9814 | 53537 | -2.4171 | 0.0000 | |
| GSE63941 | SFI1 | 9814 | 213431_x_at | 0.2181 | 0.3111 | |
| GSE77861 | SFI1 | 9814 | 215699_x_at | 0.0916 | 0.4437 | |
| GSE97050 | SFI1 | 9814 | A_23_P80278 | -0.7437 | 0.1636 | |
| SRP007169 | SFI1 | 9814 | RNAseq | 1.0526 | 0.0841 | |
| SRP064894 | SFI1 | 9814 | RNAseq | 0.8180 | 0.0003 | |
| SRP133303 | SFI1 | 9814 | RNAseq | -0.0768 | 0.6512 | |
| SRP159526 | SFI1 | 9814 | RNAseq | 0.4061 | 0.2751 | |
| SRP193095 | SFI1 | 9814 | RNAseq | 0.2447 | 0.1780 | |
| SRP219564 | SFI1 | 9814 | RNAseq | 0.2567 | 0.3268 | |
| TCGA | SFI1 | 9814 | RNAseq | 0.0634 | 0.2915 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by SFI1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SFI1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SFI1 | 9814 | 4 | 5 | 21 | |
| GSE20123 | SFI1 | 9814 | 4 | 4 | 22 | |
| GSE43470 | SFI1 | 9814 | 4 | 5 | 34 | |
| GSE46452 | SFI1 | 9814 | 31 | 1 | 27 | |
| GSE47630 | SFI1 | 9814 | 8 | 5 | 27 | |
| GSE54993 | SFI1 | 9814 | 3 | 6 | 61 | |
| GSE54994 | SFI1 | 9814 | 12 | 8 | 33 | |
| GSE60625 | SFI1 | 9814 | 5 | 0 | 6 | |
| GSE74703 | SFI1 | 9814 | 4 | 5 | 27 | |
| GSE74704 | SFI1 | 9814 | 1 | 1 | 18 | |
| TCGA | SFI1 | 9814 | 27 | 16 | 53 |
Total number of gains: 103; Total number of losses: 56; Total Number of normals: 329.
Somatic mutations of SFI1:
Generating mutation plots.
Highly correlated genes for SFI1:
Showing top 20/257 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SFI1 | FLG | 0.875379 | 3 | 0 | 3 |
| SFI1 | NCCRP1 | 0.792444 | 3 | 0 | 3 |
| SFI1 | UPK3B | 0.759833 | 3 | 0 | 3 |
| SFI1 | GIPC1 | 0.754607 | 3 | 0 | 3 |
| SFI1 | EPGN | 0.747581 | 3 | 0 | 3 |
| SFI1 | TMPRSS11A | 0.739031 | 3 | 0 | 3 |
| SFI1 | IQCF1 | 0.733808 | 4 | 0 | 3 |
| SFI1 | FNDC4 | 0.7294 | 3 | 0 | 3 |
| SFI1 | KPRP | 0.720966 | 3 | 0 | 3 |
| SFI1 | LAMB4 | 0.719911 | 4 | 0 | 4 |
| SFI1 | KRTAP20-1 | 0.715094 | 3 | 0 | 3 |
| SFI1 | OTOP3 | 0.714054 | 3 | 0 | 3 |
| SFI1 | ACER1 | 0.712394 | 3 | 0 | 3 |
| SFI1 | HMGB4 | 0.705379 | 3 | 0 | 3 |
| SFI1 | GPX6 | 0.703861 | 3 | 0 | 3 |
| SFI1 | ZC3H12D | 0.699655 | 3 | 0 | 3 |
| SFI1 | PDCL2 | 0.69812 | 3 | 0 | 3 |
| SFI1 | PHF12 | 0.693731 | 5 | 0 | 4 |
| SFI1 | ARID5A | 0.675248 | 6 | 0 | 5 |
| SFI1 | KMT2D | 0.673151 | 5 | 0 | 4 |
For details and further investigation, click here
