| Full name: peptidase D | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 19q13.11 | ||
| Entrez ID: 5184 | HGNC ID: HGNC:8840 | Ensembl Gene: ENSG00000124299 | OMIM ID: 613230 |
| Drug and gene relationship at DGIdb | |||
Expression of PEPD:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PEPD | 5184 | 202108_at | -0.1381 | 0.7927 | |
| GSE20347 | PEPD | 5184 | 202108_at | -0.5168 | 0.0058 | |
| GSE23400 | PEPD | 5184 | 202108_at | -0.0653 | 0.5158 | |
| GSE26886 | PEPD | 5184 | 202108_at | -0.5858 | 0.0089 | |
| GSE29001 | PEPD | 5184 | 202108_at | -0.3602 | 0.2631 | |
| GSE38129 | PEPD | 5184 | 202108_at | -0.3364 | 0.0172 | |
| GSE45670 | PEPD | 5184 | 202108_at | -0.4140 | 0.0168 | |
| GSE53622 | PEPD | 5184 | 16440 | -0.6927 | 0.0000 | |
| GSE53624 | PEPD | 5184 | 16440 | -0.3821 | 0.0000 | |
| GSE63941 | PEPD | 5184 | 202108_at | -0.4033 | 0.5825 | |
| GSE77861 | PEPD | 5184 | 202108_at | -0.3238 | 0.2610 | |
| GSE97050 | PEPD | 5184 | A_23_P83436 | -0.2296 | 0.3046 | |
| SRP007169 | PEPD | 5184 | RNAseq | 0.3895 | 0.3447 | |
| SRP008496 | PEPD | 5184 | RNAseq | 0.1967 | 0.5112 | |
| SRP064894 | PEPD | 5184 | RNAseq | 0.0329 | 0.8535 | |
| SRP133303 | PEPD | 5184 | RNAseq | -0.0350 | 0.9280 | |
| SRP159526 | PEPD | 5184 | RNAseq | -0.0734 | 0.7661 | |
| SRP193095 | PEPD | 5184 | RNAseq | -0.8577 | 0.0000 | |
| SRP219564 | PEPD | 5184 | RNAseq | -0.1389 | 0.7532 | |
| TCGA | PEPD | 5184 | RNAseq | -0.0325 | 0.5304 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PEPD expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PEPD:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PEPD | 5184 | 7 | 6 | 17 | |
| GSE20123 | PEPD | 5184 | 7 | 5 | 18 | |
| GSE43470 | PEPD | 5184 | 5 | 6 | 32 | |
| GSE46452 | PEPD | 5184 | 47 | 1 | 11 | |
| GSE47630 | PEPD | 5184 | 8 | 6 | 26 | |
| GSE54993 | PEPD | 5184 | 17 | 3 | 50 | |
| GSE54994 | PEPD | 5184 | 8 | 9 | 36 | |
| GSE60625 | PEPD | 5184 | 9 | 0 | 2 | |
| GSE74703 | PEPD | 5184 | 5 | 4 | 27 | |
| GSE74704 | PEPD | 5184 | 6 | 3 | 11 | |
| TCGA | PEPD | 5184 | 18 | 12 | 66 |
Total number of gains: 137; Total number of losses: 55; Total Number of normals: 296.
Somatic mutations of PEPD:
Generating mutation plots.
Highly correlated genes for PEPD:
Showing top 20/605 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PEPD | USP24 | 0.78873 | 3 | 0 | 3 |
| PEPD | ING4 | 0.781007 | 3 | 0 | 3 |
| PEPD | NFKBIL1 | 0.76881 | 3 | 0 | 3 |
| PEPD | PCNT | 0.745968 | 3 | 0 | 3 |
| PEPD | MEAF6 | 0.733606 | 3 | 0 | 3 |
| PEPD | CIDEB | 0.729095 | 3 | 0 | 3 |
| PEPD | ARL6 | 0.725801 | 3 | 0 | 3 |
| PEPD | TCEANC2 | 0.719441 | 3 | 0 | 3 |
| PEPD | OMA1 | 0.717386 | 3 | 0 | 3 |
| PEPD | MED8 | 0.71671 | 3 | 0 | 3 |
| PEPD | ECHS1 | 0.712579 | 4 | 0 | 3 |
| PEPD | SCFD2 | 0.708432 | 3 | 0 | 3 |
| PEPD | ZNF862 | 0.707622 | 3 | 0 | 3 |
| PEPD | COPZ1 | 0.707486 | 4 | 0 | 4 |
| PEPD | MBNL3 | 0.706783 | 4 | 0 | 4 |
| PEPD | ZNF564 | 0.704044 | 4 | 0 | 3 |
| PEPD | RRAGC | 0.703585 | 3 | 0 | 3 |
| PEPD | PPARG | 0.698058 | 4 | 0 | 3 |
| PEPD | GGA3 | 0.697552 | 4 | 0 | 4 |
| PEPD | RPS6KA3 | 0.694965 | 4 | 0 | 3 |
For details and further investigation, click here
