| Full name: potassium voltage-gated channel subfamily C member 3 | Alias Symbol: Kv3.3 | ||
| Type: protein-coding gene | Cytoband: 19q13.33 | ||
| Entrez ID: 3748 | HGNC ID: HGNC:6235 | Ensembl Gene: ENSG00000131398 | OMIM ID: 176264 |
| Drug and gene relationship at DGIdb | |||
Expression of KCNC3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KCNC3 | 3748 | 230531_at | 0.1044 | 0.7262 | |
| GSE20347 | KCNC3 | 3748 | 207600_at | -0.0456 | 0.5376 | |
| GSE23400 | KCNC3 | 3748 | 207600_at | -0.1783 | 0.0000 | |
| GSE26886 | KCNC3 | 3748 | 230531_at | 0.4201 | 0.0099 | |
| GSE29001 | KCNC3 | 3748 | 207600_at | -0.0485 | 0.7396 | |
| GSE38129 | KCNC3 | 3748 | 207600_at | -0.1021 | 0.1297 | |
| GSE45670 | KCNC3 | 3748 | 230531_at | -0.0180 | 0.9042 | |
| GSE53622 | KCNC3 | 3748 | 5192 | 0.3843 | 0.0000 | |
| GSE53624 | KCNC3 | 3748 | 5192 | -0.0054 | 0.9488 | |
| GSE63941 | KCNC3 | 3748 | 230531_at | 0.7207 | 0.0006 | |
| GSE77861 | KCNC3 | 3748 | 230531_at | 0.0024 | 0.9897 | |
| GSE97050 | KCNC3 | 3748 | A_23_P101516 | -0.0098 | 0.9698 | |
| SRP133303 | KCNC3 | 3748 | RNAseq | 0.4843 | 0.1010 | |
| SRP159526 | KCNC3 | 3748 | RNAseq | 1.6533 | 0.0007 | |
| SRP219564 | KCNC3 | 3748 | RNAseq | 1.3198 | 0.0246 | |
| TCGA | KCNC3 | 3748 | RNAseq | 0.6340 | 0.0008 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by KCNC3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KCNC3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KCNC3 | 3748 | 4 | 4 | 22 | |
| GSE20123 | KCNC3 | 3748 | 4 | 3 | 23 | |
| GSE43470 | KCNC3 | 3748 | 4 | 12 | 27 | |
| GSE46452 | KCNC3 | 3748 | 45 | 1 | 13 | |
| GSE47630 | KCNC3 | 3748 | 10 | 6 | 24 | |
| GSE54993 | KCNC3 | 3748 | 17 | 4 | 49 | |
| GSE54994 | KCNC3 | 3748 | 4 | 14 | 35 | |
| GSE60625 | KCNC3 | 3748 | 9 | 0 | 2 | |
| GSE74703 | KCNC3 | 3748 | 4 | 8 | 24 | |
| GSE74704 | KCNC3 | 3748 | 4 | 1 | 15 | |
| TCGA | KCNC3 | 3748 | 14 | 19 | 63 |
Total number of gains: 119; Total number of losses: 72; Total Number of normals: 297.
Somatic mutations of KCNC3:
Generating mutation plots.
Highly correlated genes for KCNC3:
Showing top 20/993 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KCNC3 | PRSS38 | 0.83453 | 3 | 0 | 3 |
| KCNC3 | YY2 | 0.824647 | 3 | 0 | 3 |
| KCNC3 | MRGPRG | 0.824415 | 3 | 0 | 3 |
| KCNC3 | DCDC1 | 0.81446 | 3 | 0 | 3 |
| KCNC3 | OR2B11 | 0.811846 | 3 | 0 | 3 |
| KCNC3 | TSSK3 | 0.808194 | 3 | 0 | 3 |
| KCNC3 | NKX6-3 | 0.800287 | 3 | 0 | 3 |
| KCNC3 | OR2T1 | 0.791205 | 3 | 0 | 3 |
| KCNC3 | TTLL9 | 0.790122 | 4 | 0 | 4 |
| KCNC3 | LBX2 | 0.78213 | 3 | 0 | 3 |
| KCNC3 | CHST10 | 0.772948 | 3 | 0 | 3 |
| KCNC3 | FAM71F1 | 0.766749 | 3 | 0 | 3 |
| KCNC3 | BBC3 | 0.760096 | 3 | 0 | 3 |
| KCNC3 | GPR150 | 0.75954 | 3 | 0 | 3 |
| KCNC3 | C1QL2 | 0.758789 | 3 | 0 | 3 |
| KCNC3 | BSX | 0.754897 | 3 | 0 | 3 |
| KCNC3 | C19orf71 | 0.751003 | 3 | 0 | 3 |
| KCNC3 | KRTAP10-12 | 0.748299 | 3 | 0 | 3 |
| KCNC3 | PLA2G2C | 0.745902 | 3 | 0 | 3 |
| KCNC3 | OR2A5 | 0.745791 | 3 | 0 | 3 |
For details and further investigation, click here
